Skip Header

Contribute Send feedback
Read comments (?) or add your own

A7Z4H0 (A7Z4H0_BACA2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Dihydroorotase RuleBase RU003441
EC=3.5.2.3 RuleBase RU003441
Gene names
Name:pyrC EMBL ABS73896.1
Ordered Locus Names:RBAM_015330
OrganismBacillus amyloliquefaciens (strain FZB42) [Complete proteome] [HAMAP]
Taxonomic identifier326423 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length428 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. RuleBase RU003441 SAAS SAAS002195

Cofactor

Binds 2 zinc ions per subunit By similarity. RuleBase RU003441 SAAS SAAS002195

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. RuleBase RU003441 SAAS SAAS002195

Subunit structure

Homodimer By similarity. SAAS SAAS002195

Sequence similarities

Belongs to the DHOase family. Type 2 subfamily. RuleBase RU003441

Sequences

Sequence LengthMass (Da)Tools
A7Z4H0 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 55C23A2A465AF4C2

FASTA42846,655
        10         20         30         40         50         60 
MSYLIKNGWM LNEQGEKVAQ DIRVTGEFIS ETGLLTAKDG ETVIDAEGLF VSPGLVDLHV 

        70         80         90        100        110        120 
HFREPGGEKK ETIETGSKAA ARGGFTTVAA MPNTRPVPDT KEQMEWLQNR IKETSSVRVL 

       130        140        150        160        170        180 
PYASITIRQT GEEMTDFKAL HEAGAFAFTD DGVGVQTAGM MYEAMKRAAS MNKAIVAHCE 

       190        200        210        220        230        240 
DNSLIYGGSV HEGSFSKANG LNGIPSICEA VHIARDVLLA EAAGCHYHVC HISTKESVRA 

       250        260        270        280        290        300 
VRDAKKAGIR VTAEVSPHHL LLCDEDIPGL DTNFKMNPPL RSKEDREALI EGLLDGTIDF 

       310        320        330        340        350        360 
IATDHAPHTE EEKNTDMKLA PFGIVGLETA FPLLYTHFVK NGEWTLKQLV DFMTVKPCEA 

       370        380        390        400        410        420 
FALPYGTLAP GAPADITLID LEKEAAIDKD TFLSKGKNTP FNKMKCFGWP VATMAAGKLA 


YEEGRLVK

« Hide

References

[1]"Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42."
Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K., Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H., Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H., Strittmatter A., Gottschalk G., Borriss R.
Nat. Biotechnol. 25:1007-1014(2007) [PubMed: 17704766] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000560 Genomic DNA. Translation: ABS73896.1.
RefSeqYP_001421127.1. NC_009725.1.

3D structure databases

ProteinModelPortalA7Z4H0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7Z4H0.

Protein family/group databases

MEROPSM38.972.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000006547; EBBACP00000006425; EBBACG00000006539.
GeneID5462419.
GenomeReviewsGene locus RBAM_015330 in contig CP000560_GR.
KEGGbay:RBAM_015330.
PATRIC18748126. VBIBacAmy31356_1539.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0044.
GeneTreeEBGT00050000001626.
HOGENOMHBG724623.
OMACDVHPVG.
ProtClustDBCLSK887279.

Family and domain databases

HAMAPMF_00220_B. PyrC_type2_B.
[Tree]
InterProIPR006680. Amidohydro_1.
IPR004722. DHOase.
IPR002195. Dihydroorotase_CS.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
KOK01465.
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMSSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMsTIGR00857. PyrC_multi. 1 hit.
PROSITEPS00482. DIHYDROOROTASE_1. 1 hit.
PS00483. DIHYDROOROTASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7Z4H0_BACA2
AccessionPrimary (citable) accession number: A7Z4H0
Entry history
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info