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A7Z168 (A7Z168_BACA2) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-pyrroline-5-carboxylate dehydrogenase 1 HAMAP MF_00733
Short name=P5C dehydrogenase 1 HAMAP MF_00733
EC=1.5.1.12 HAMAP MF_00733
Gene names
Name:ycgN EMBL ABS72744.1
Synonyms:rocA1 HAMAP MF_00733
Ordered Locus Names:RBAM_003450
OrganismBacillus amyloliquefaciens (strain FZB42) [Complete proteome] [HAMAP]
Taxonomic identifier326423 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length515 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-1-pyrroline-5-carboxylate + NAD(P)+ + 2 H2O = L-glutamate + NAD(P)H. HAMAP MF_00733

Pathway

Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2. HAMAP MF_00733

Sequence similarities

Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Belongs to the aldehyde dehydrogenase family. RocA subfamily. HAMAP MF_00733

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2861 By similarity HAMAP MF_00733
Active site3201 By similarity HAMAP MF_00733

Sequences

Sequence LengthMass (Da)Tools
A7Z168 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: ED261FF2325AED64

FASTA51556,411
        10         20         30         40         50         60 
MTTPYKHEPF TNFQDQSNVE EFKKALATVN EYLGKDYPLV INGEKVETEA KIVSINPADK 

        70         80         90        100        110        120 
EEVVGKVSKA SQEHAEQAIE AAAKAFEEWR YTSPEERAAV LFRAAAKVRR RKHEFSALLV 

       130        140        150        160        170        180 
KEAGKPWNEA DADTAEAIDF MEYYARQMIE LAKGKPVNSR EGEKNQYVYT PTGVTVVIPP 

       190        200        210        220        230        240 
WNFLFAIMAG TTVAPIVTGN TVVLKPASAT PVIAAKFVEV LEESGLPKGV VNFVPGSGAE 

       250        260        270        280        290        300 
VGDYLVDHPK TSLITFTGSR EVGTRIFERA AKVQPGQQHL KRVIAEMGGK DTVVVDEDAD 

       310        320        330        340        350        360 
IELAAQSIFT SAFGFAGQKC SAGSRAVVHE KVYDQVLERV IEITESKVTA KPDSADVYMG 

       370        380        390        400        410        420 
PVIDQGSYDK IMSYIEIGKE EGRLVSGGTG DDSKGYFIKP TIFADLDPKA RLMQEEIFGP 

       430        440        450        460        470        480 
VVAFSKVSNF DEALEVANNT EYGLTGAVIT NNRKHIERAK QEFHVGNLYF NRNCTGAIVG 

       490        500        510 
YHPFGGFKMS GTDSKAGGPD YLALHMQAKT ISEMF

« Hide

References

[1]"Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42."
Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K., Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H., Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H., Strittmatter A., Gottschalk G., Borriss R.
Nat. Biotechnol. 25:1007-1014(2007) [PubMed: 17704766] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000560 Genomic DNA. Translation: ABS72744.1.
RefSeqYP_001419975.1. NC_009725.1.

3D structure databases

ProteinModelPortalA7Z168.
SMRA7Z168. Positions 3-515.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7Z168.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBACT00000006452; EBBACP00000006330; EBBACG00000006444.
GeneID5461437.
GenomeReviewsGene locus RBAM_003450 in contig CP000560_GR.
KEGGbay:RBAM_003450.
PATRIC18745597. VBIBacAmy31356_0311.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
GeneTreeEBGT00070000031871.
HOGENOMHBG752218.
OMATPYKHEP.
ProtClustDBPRK03137.

Family and domain databases

HAMAPMF_00733. RocA.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR005932. Delta1-pyrroline-5-COlate_DH-2.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK00294.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR01237. D1pyr5carbox2. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7Z168_BACA2
AccessionPrimary (citable) accession number: A7Z168
Entry history
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info