A7Z0H6 (PTH_BACA2) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peptidyl-tRNA hydrolase
Short name=PTH
EC=3.1.1.29

Gene names

Name:	pth
Ordered Locus Names:	RBAM_000620

Organism

Bacillus amyloliquefaciens (strain FZB42) [Complete proteome] [HAMAP]

Taxonomic identifier

326423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	188 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP MF_00083
Catalytic activity	N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083
Subunit structure	Monomer By similarity. HAMAP MF_00083
Subcellular location	Cytoplasm By similarity HAMAP MF_00083.
Sequence similarities	Belongs to the PTH family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	aminoacyl-tRNA hydrolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 188	188	Peptidyl-tRNA hydrolase HAMAP MF_00083		PRO_1000010562

Sequences

	Sequence		Length	Mass (Da)
	A7Z0H6 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: C34185AB648BF4D3	FASTA	188	20,814
	10 20 30 40 50 60 MLVIAGLGNP GKTYENTRHN VGFMAIDELS KEWNIELNKT KFNGLYGMGF VSGKKVLLVK 70 80 90 100 110 120 PLTYMNLSGE CLRPILDYYD ADHEDLKVIY DDLDLPTGKI RLRTKGSAGG HNGIKSLIQH 130 140 150 160 170 180 LGTPEFDRVR IGIGRPVNGM KVVDYVLGAF TKEEAPHIND AVSKTVKACE ASLTKPFLEV MNEFNANV

References

[1]

"Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42." Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K., Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H., Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H., Strittmatter A., Gottschalk G., Borriss R. Nat. Biotechnol. 25:1007-1014(2007) [PubMed: 17704766] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: FZB42.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000560 Genomic DNA. Translation: ABS72502.1.
RefSeq	YP_001419733.1. NC_009725.1.
3D structure databases
ProteinModelPortal	A7Z0H6.
ModBase	Search...
Protein-protein interaction databases
STRING	A7Z0H6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000005463; EBBACP00000005341; EBBACG00000005455.
GeneID	5462750.
GenomeReviews	Gene locus RBAM_000620 in contig CP000560_GR.
KEGG	bay:RBAM_000620.
PATRIC	18745017. VBIBacAmy31356_0057.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0193.
GeneTree	EBGT00050000001189.
HOGENOM	HBG610927.
OMA	FNILMNG.
ProtClustDB	PRK05426.
Enzyme and pathway databases
BioCyc	BAMY326423:RBAM_000620-MONOMER.
Family and domain databases
HAMAP	MF_00083. Pept_tRNA_hydro_bact. [Tree]
InterPro	IPR001328. Pept_tRNA_hydro. IPR018171. Pept_tRNA_hydro_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit.
KO	K01056.
PANTHER	PTHR17224. Pept_tRNA_hydro. 1 hit.
Pfam	PF01195. Pept_tRNA_hydro. 1 hit. [Graphical view]
SUPFAM	SSF53178. Pept_tRNA_hydro. 1 hit.
TIGRFAMs	TIGR00447. Pth. 1 hit.
PROSITE	PS01195. PEPT_TRNA_HYDROL_1. 1 hit. PS01196. PEPT_TRNA_HYDROL_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PTH_BACA2

Accession

Primary (citable) accession number: A7Z0H6

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 23, 2007
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program