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Protein

Transcription factor jun-D

Gene

JUND

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Transcription factor binding AP-1 sites.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor jun-D
Gene namesi
Name:JUND
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 347347Transcription factor jun-DPRO_0000311123Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei251 – 2511PhosphoserineBy similarity
Modified residuei255 – 2551PhosphoserineBy similarity
Modified residuei259 – 2591PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiA7YY54.

Interactioni

Subunit structurei

Binds DNA as a dimer. Interacts with MEN1.By similarity

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliA7YY54.
SMRiA7YY54. Positions 269-330.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini268 – 33164bZIPPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni268 – 29528Basic motifPROSITE-ProRule annotationAdd
BLAST
Regioni296 – 32429Leucine-zipperPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the bZIP family. Jun subfamily.Curated
Contains 1 bZIP (basic-leucine zipper) domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000006648.
HOVERGENiHBG001722.
InParanoidiA7YY54.
KOiK04449.

Family and domain databases

Gene3Di1.10.880.10. 1 hit.
InterProiIPR004827. bZIP.
IPR005643. JNK.
IPR029823. JunD.
IPR002112. Leuzip_Jun.
IPR008917. TF_DNA-bd.
[Graphical view]
PANTHERiPTHR11462:SF7. PTHR11462:SF7. 2 hits.
PfamiPF00170. bZIP_1. 1 hit.
PF03957. Jun. 1 hit.
[Graphical view]
PRINTSiPR00043. LEUZIPPRJUN.
SMARTiSM00338. BRLZ. 1 hit.
[Graphical view]
SUPFAMiSSF47454. SSF47454. 1 hit.
PROSITEiPS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7YY54-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METPFYGDEA LSGLGGGGSS SGGGGSFASP GRLFPGAPPT AAPGSMMKKD
60 70 80 90 100
ALTLSLSEQV AAALKPAAAP PPGPLRTDGA PGTAPPDGLL ASPELGLLKL
110 120 130 140 150
ASPELERLII QSNGLVTTTP TSTQFLYPKV AASEEQEFAE GFVKALEDLH
160 170 180 190 200
KQNQLSAGAA SAAAAAGGPS GTAAGAAPPS ELAPAAATPE APVYANLSSY
210 220 230 240 250
AGGTGSAGGA ATVAFAAEPV PFPPPPPPGT LGPPRLAALK DEPQTVPDVP
260 270 280 290 300
SFGESPPLSP IDMDTQERIK AERKRLRNRI AASKCRKRKL ERISRLEEKV
310 320 330 340
KTLKSQNTEL ASTASLLREQ VAQLKQKVLS HVNSGCQLLP QHQVPAY
Length:347
Mass (Da):35,352
Last modified:October 23, 2007 - v1
Checksum:iAEF47BCE2ABC4B91
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC151336 mRNA. Translation: AAI51337.1.
RefSeqiNP_001096723.1. NM_001103253.1.
UniGeneiBt.27169.

Genome annotation databases

GeneIDi517192.
KEGGibta:517192.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC151336 mRNA. Translation: AAI51337.1.
RefSeqiNP_001096723.1. NM_001103253.1.
UniGeneiBt.27169.

3D structure databases

ProteinModelPortaliA7YY54.
SMRiA7YY54. Positions 269-330.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiA7YY54.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi517192.
KEGGibta:517192.

Organism-specific databases

CTDi3727.

Phylogenomic databases

HOGENOMiHOG000006648.
HOVERGENiHBG001722.
InParanoidiA7YY54.
KOiK04449.

Family and domain databases

Gene3Di1.10.880.10. 1 hit.
InterProiIPR004827. bZIP.
IPR005643. JNK.
IPR029823. JunD.
IPR002112. Leuzip_Jun.
IPR008917. TF_DNA-bd.
[Graphical view]
PANTHERiPTHR11462:SF7. PTHR11462:SF7. 2 hits.
PfamiPF00170. bZIP_1. 1 hit.
PF03957. Jun. 1 hit.
[Graphical view]
PRINTSiPR00043. LEUZIPPRJUN.
SMARTiSM00338. BRLZ. 1 hit.
[Graphical view]
SUPFAMiSSF47454. SSF47454. 1 hit.
PROSITEiPS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Crossbred X Angus.
    Tissue: Liver.

Entry informationi

Entry nameiJUND_BOVIN
AccessioniPrimary (citable) accession number: A7YY54
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: October 23, 2007
Last modified: June 8, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.