Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A7YWU3

- RPP40_BOVIN

UniProt

A7YWU3 - RPP40_BOVIN

Protein

Ribonuclease P protein subunit p40

Gene

RPP40

Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 2 (25 Nov 2008)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.By similarity

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-EC

    GO - Biological processi

    1. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    tRNA processing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein subunit p40 (EC:3.1.26.5)
    Short name:
    RNaseP protein p40
    Gene namesi
    Name:RPP40
    OrganismiBos taurus (Bovine)
    Taxonomic identifieri9913 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
    ProteomesiUP000009136: Unplaced

    Subcellular locationi

    Nucleusnucleolus Curated

    GO - Cellular componenti

    1. nucleolus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 303303Ribonuclease P protein subunit p40PRO_0000354075Add
    BLAST

    Interactioni

    Subunit structurei

    RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40.By similarity

    Protein-protein interaction databases

    STRINGi9913.ENSBTAP00000004325.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG42164.
    HOGENOMiHOG000006875.
    HOVERGENiHBG055018.
    InParanoidiA7YWU3.
    KOiK14530.

    Family and domain databases

    InterProiIPR013893. RNase_P_Rpp40.
    [Graphical view]
    PfamiPF08584. Ribonuc_P_40. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7YWU3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGFGPYYFVK GLPLYELITH EFINTFVKKG SCYALTYNTN IDEDNTVALL    50
    PNGKLILSLD KDTYEETGLQ GCPSQYSGRK TMRFIVSIDL MDLSSNLDSK 100
    KYKRVSWAFK EKKPLKFDFL LAWHQTGAEG STMMSYFSGY GIQEHQPKIA 150
    LSTTPDLRCP VLRSGLLGGE PEAACSAHEL FDWLGAVFSH ADLNNEPYNF 200
    VSTYCCPQPS SVVAQASLCS VTGFLLPERI CVLLEQLCRY FDEPKLAPWV 250
    TLSVQGFADS PVSWRESEHG FQKGGEHLYN FVIFNNRDYW LQMAVGADDD 300
    CPP 303
    Length:303
    Mass (Da):34,096
    Last modified:November 25, 2008 - v2
    Checksum:iF62D4C320821BD4B
    GO

    Sequence cautioni

    The sequence AAI34789.1 differs from that shown. Reason: Erroneous initiation.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC134788 mRNA. Translation: AAI34789.1. Different initiation.
    RefSeqiNP_001098872.1. NM_001105402.2.
    UniGeneiBt.83862.

    Genome annotation databases

    GeneIDi531274.
    KEGGibta:531274.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC134788 mRNA. Translation: AAI34789.1 . Different initiation.
    RefSeqi NP_001098872.1. NM_001105402.2.
    UniGenei Bt.83862.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9913.ENSBTAP00000004325.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 531274.
    KEGGi bta:531274.

    Organism-specific databases

    CTDi 10799.

    Phylogenomic databases

    eggNOGi NOG42164.
    HOGENOMi HOG000006875.
    HOVERGENi HBG055018.
    InParanoidi A7YWU3.
    KOi K14530.

    Miscellaneous databases

    NextBioi 20875426.

    Family and domain databases

    InterProi IPR013893. RNase_P_Rpp40.
    [Graphical view ]
    Pfami PF08584. Ribonuc_P_40. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Mammalian Gene Collection (MGC) project
      Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: Hereford.
      Tissue: Fetal pons.

    Entry informationi

    Entry nameiRPP40_BOVIN
    AccessioniPrimary (citable) accession number: A7YWU3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 25, 2008
    Last sequence update: November 25, 2008
    Last modified: October 1, 2014
    This is version 37 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3