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A7YWU3

- RPP40_BOVIN

UniProt

A7YWU3 - RPP40_BOVIN

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Protein
Ribonuclease P protein subunit p40
Gene
RPP40
Organism
Bos taurus (Bovine)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p40 (EC:3.1.26.5)
Short name:
RNaseP protein p40
Gene namesi
Name:RPP40
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
ProteomesiUP000009136: Unplaced

Subcellular locationi

Nucleusnucleolus Reviewed prediction

GO - Cellular componenti

  1. nucleolus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Ribonuclease P protein subunit p40
PRO_0000354075Add
BLAST

Interactioni

Subunit structurei

RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40 By similarity.

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000004325.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG42164.
HOGENOMiHOG000006875.
HOVERGENiHBG055018.
InParanoidiA7YWU3.
KOiK14530.

Family and domain databases

InterProiIPR013893. RNase_P_Rpp40.
[Graphical view]
PfamiPF08584. Ribonuc_P_40. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7YWU3-1 [UniParc]FASTAAdd to Basket

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MGFGPYYFVK GLPLYELITH EFINTFVKKG SCYALTYNTN IDEDNTVALL    50
PNGKLILSLD KDTYEETGLQ GCPSQYSGRK TMRFIVSIDL MDLSSNLDSK 100
KYKRVSWAFK EKKPLKFDFL LAWHQTGAEG STMMSYFSGY GIQEHQPKIA 150
LSTTPDLRCP VLRSGLLGGE PEAACSAHEL FDWLGAVFSH ADLNNEPYNF 200
VSTYCCPQPS SVVAQASLCS VTGFLLPERI CVLLEQLCRY FDEPKLAPWV 250
TLSVQGFADS PVSWRESEHG FQKGGEHLYN FVIFNNRDYW LQMAVGADDD 300
CPP 303
Length:303
Mass (Da):34,096
Last modified:November 25, 2008 - v2
Checksum:iF62D4C320821BD4B
GO

Sequence cautioni

The sequence AAI34789.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC134788 mRNA. Translation: AAI34789.1. Different initiation.
RefSeqiNP_001098872.1. NM_001105402.2.
UniGeneiBt.83862.

Genome annotation databases

GeneIDi531274.
KEGGibta:531274.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC134788 mRNA. Translation: AAI34789.1 . Different initiation.
RefSeqi NP_001098872.1. NM_001105402.2.
UniGenei Bt.83862.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 9913.ENSBTAP00000004325.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 531274.
KEGGi bta:531274.

Organism-specific databases

CTDi 10799.

Phylogenomic databases

eggNOGi NOG42164.
HOGENOMi HOG000006875.
HOVERGENi HBG055018.
InParanoidi A7YWU3.
KOi K14530.

Miscellaneous databases

NextBioi 20875426.

Family and domain databases

InterProi IPR013893. RNase_P_Rpp40.
[Graphical view ]
Pfami PF08584. Ribonuc_P_40. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Mammalian Gene Collection (MGC) project
    Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Hereford.
    Tissue: Fetal pons.

Entry informationi

Entry nameiRPP40_BOVIN
AccessioniPrimary (citable) accession number: A7YWU3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: November 25, 2008
Last modified: April 16, 2014
This is version 36 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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