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A7YWU3 (RPP40_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein subunit p40

Short name=RNaseP protein p40
EC=3.1.26.5
Gene names
Name:RPP40
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

Protein attributes

Sequence length303 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

Subunit structure

RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40 By similarity.

Subcellular location

Nucleusnucleolus Potential.

Sequence caution

The sequence AAI34789.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentNucleus
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleolus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 303303Ribonuclease P protein subunit p40
PRO_0000354075

Sequences

Sequence LengthMass (Da)Tools
A7YWU3 [UniParc].

Last modified November 25, 2008. Version 2.
Checksum: F62D4C320821BD4B

FASTA30334,096
        10         20         30         40         50         60 
MGFGPYYFVK GLPLYELITH EFINTFVKKG SCYALTYNTN IDEDNTVALL PNGKLILSLD 

        70         80         90        100        110        120 
KDTYEETGLQ GCPSQYSGRK TMRFIVSIDL MDLSSNLDSK KYKRVSWAFK EKKPLKFDFL 

       130        140        150        160        170        180 
LAWHQTGAEG STMMSYFSGY GIQEHQPKIA LSTTPDLRCP VLRSGLLGGE PEAACSAHEL 

       190        200        210        220        230        240 
FDWLGAVFSH ADLNNEPYNF VSTYCCPQPS SVVAQASLCS VTGFLLPERI CVLLEQLCRY 

       250        260        270        280        290        300 
FDEPKLAPWV TLSVQGFADS PVSWRESEHG FQKGGEHLYN FVIFNNRDYW LQMAVGADDD 


CPP 

« Hide

References

[1]NIH - Mammalian Gene Collection (MGC) project
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: Hereford.
Tissue: Fetal pons.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BC134788 mRNA. Translation: AAI34789.1. Different initiation.
RefSeqNP_001098872.1. NM_001105402.2.
UniGeneBt.83862.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9913.ENSBTAP00000004325.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID531274.
KEGGbta:531274.

Organism-specific databases

CTD10799.

Phylogenomic databases

eggNOGNOG42164.
HOGENOMHOG000006875.
HOVERGENHBG055018.
InParanoidA7YWU3.
KOK14530.

Family and domain databases

InterProIPR013893. RNase_P_Rpp40.
[Graphical view]
PfamPF08584. Ribonuc_P_40. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20875426.

Entry information

Entry nameRPP40_BOVIN
AccessionPrimary (citable) accession number: A7YWU3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: November 25, 2008
Last modified: April 16, 2014
This is version 36 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program