Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

PIM2 protein

Gene

PIM2

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei121ATPUniRule annotation1
Binding sitei177ATP; via carbonyl oxygenUniRule annotation1
Binding sitei184ATPUniRule annotation1
Active sitei223Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
PIM2 proteinImported
Submitted name:
Pim-2 proto-oncogene, serine/threonine kinaseImported
Gene namesi
Name:PIM2Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Chromosome X

Organism-specific databases

VGNCiVGNC:32900 PIM2

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSBTAG00000004597

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000006032

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini92 – 346Protein kinaseInterPro annotationAdd BLAST255

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0583 Eukaryota
COG0515 LUCA
GeneTreeiENSGT00760000119045
HOGENOMiHOG000231357
HOVERGENiHBG106681
KOiK08806
OMAiQQWARLP
OrthoDBiEOG091G0IMW
TreeFamiTF320810

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR017348 PIM1/2/3
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
PIRSFiPIRSF037993 STPK_Pim-1, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Fragment.

A7YW25-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
VASGLARAAN LNIALFAGPS GPPVSLPSIL APPSPGSPDS LPRASTPCGL
60 70 80 90 100
SGLNLRSSSS MLTKPLQGLP VAPMTPTPLP GGKDREAFEA EYQLGPLLGK
110 120 130 140 150
GGFGTVFAGH RVTDRLQVAI KVIPRNRVLG WSPLSDSVAC PLEVALLWKV
160 170 180 190 200
GAGGGHPGVI RLLDWFETPE GFMLVLERPL PAQDLFDYIT EQGPLGEGRS
210 220 230 240 250
RCLFAQVVAA VRHCHARGVV HRDIKDENIL MDLRRGCTKL IDFGSGALLH
260 270 280 290 300
DEPYTDFDGT RVYSPPEWIS RHQYHALPAT VWSLGILLYD MVCGDIPFER
310 320 330 340 350
DQEILEAELH FPAHVSPDCC ALIRRCLAPK PSARPSLEEI LLDPWMQTPA
360 370
EDASLNTPKG GPTPLDWSLL P
Length:371
Mass (Da):40,049
Last modified:October 23, 2007 - v1
Checksum:i18A8E043B029B8EC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DAAA02073075 Genomic DNA No translation available.
BC134436 mRNA Translation: AAI34437.1
RefSeqiNP_001193307.1, NM_001206378.1
UniGeneiBt.20365

Genome annotation databases

EnsembliENSBTAT00000006032; ENSBTAP00000006032; ENSBTAG00000004597
GeneIDi508424
KEGGibta:508424

Similar proteinsi

Entry informationi

Entry nameiA7YW25_BOVIN
AccessioniPrimary (citable) accession number: A7YW25
Entry historyiIntegrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: March 28, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health