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A7XZY7

- A7XZY7_HUMAN

UniProt

A7XZY7 - A7XZY7_HUMAN

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Protein
Submitted name:

Intersectin 1 short form variant 4

Gene
ITSN1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Intersectin 1 short form variant 4Imported
Gene namesi
Name:ITSN1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. plasma membrane Source: HPA
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiA7XZY7.

Expressioni

Gene expression databases

ArrayExpressiA7XZY7.
BgeeiA7XZY7.

Structurei

3D structure databases

ProteinModelPortaliA7XZY7.
SMRiA7XZY7. Positions 876-934, 968-1023, 1033-1177.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000010175.
HOVERGENiHBG052159.

Family and domain databases

Gene3Di1.10.238.10. 2 hits.
InterProiIPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR001452. SH3_domain.
IPR013315. Spectrin_alpha_SH3.
[Graphical view]
PfamiPF14604. SH3_9. 5 hits.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
PR01887. SPECTRNALPHA.
SMARTiSM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 5 hits.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 5 hits.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7XZY7-1 [UniParc]FASTAAdd to Basket

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MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ     50
SGLPQPVLAQ IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP 100
VMKQQPVAIS SAPAFAAVPP LANGAPPVIQ PLPAFAHPAA TLPKSSSFSR 150
SGPGSQLNTK LQKAQSFDVA SVPPVAEWAV PQSSRLKYRQ LFNSHDKTMS 200
GHLTGPQART ILMQSSLPQA QLASIWNLSD IDQDGKLTAE EFILAMHLID 250
VAMSGQPLPP VLPPEYIPPS FRRVRSGSGI SVISSTSVDQ RLPEEPVLED 300
EQQQLEKKLP VTFEDKKREN FERGNLELEK RRQALLEQQR KEQERLAQLE 350
RAEQERKERE RQEQERKRQL ELEKQLEKQR ELERQREEER RKEIERREAA 400
KRELERQRQL EWERNRRQEL LNQRNKEQED IVVLKAKKKT LEFELEALND 450
KKHQLEGKLQ DIRCRLTTQR QEIESTNKSR ELRIAEITHL QQQLQESQQM 500
LGRLIPEKQI LNDQLKQVQQ NSLHRDSLVT LKRALEAKEL ARQHLRDQLD 550
EVEKETRSKL QEIDIFNNQL KELREIHNKQ QLQKQKSMEA ERLKQKEQER 600
KIIELEKQKE EAQRRAQERD KQWLEHVQQE DEHQRPRKLH EEEKLKREES 650
VKKKDGEEKG KQEAQDKLGR LFHQHQEPAK PAVQAPWSTA EKGPLTISAQ 700
ENVKVVYYRA LYPFESRSHD EITIQPGDIV MVKGEWVDES QTGEPGWLGG 750
ELKGKTGWFP ANYAEKIPEN EVPAPVKPVT DSTSAPAPKL ALRETPAPLA 800
VTSSEPSTTP NNWADFSSTW PTSTNEKPET DNWDAWAAQP SLTVPSAGQL 850
RQRSAFTPAT ATGSSPSPVL GQGEKVEGLQ AQALYPWRAK KDNHLNFNKN 900
DVITVLEQQD MWWFGEVQGQ KGWFPKSYVK LISGPIRKST SMDSGSSESP 950
ASLKRVASPA AKPVVSGEEF IAMYTYESSE QGDLTFQQGD VILVTKKDGD 1000
WWTGTVGDKA GVFPSNYVRL KDSEGSGTAG KTGSLGKKPE IAQVIASYTA 1050
TGPEQLTLAP GQLILIRKKN PGGWWEGELQ ARGKKRQIGW FPANYVKLLS 1100
PGTSKITPTE PPKSTALAAV CQVIGMYDYT AQNDDELAFN KGQIINVLNK 1150
EDPDWWKGEV NGQVGLFPSN YVKLTTDMDP SQQ 1183
Length:1,183
Mass (Da):134,159
Last modified:October 23, 2007 - v1
Checksum:i8A762140D073A09C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU107386 mRNA. Translation: ABV03351.1.
UniGeneiHs.160324.

Genome annotation databases

UCSCiuc010gmi.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
EU107386 mRNA. Translation: ABV03351.1 .
UniGenei Hs.160324.

3D structure databases

ProteinModelPortali A7XZY7.
SMRi A7XZY7. Positions 876-934, 968-1023, 1033-1177.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi A7XZY7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc010gmi.3. human.

Phylogenomic databases

HOGENOMi HOG000010175.
HOVERGENi HBG052159.

Miscellaneous databases

GenomeRNAii 6453.
NextBioi 35463564.

Gene expression databases

ArrayExpressi A7XZY7.
Bgeei A7XZY7.

Family and domain databases

Gene3Di 1.10.238.10. 2 hits.
InterProi IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR000261. EPS15_homology.
IPR001452. SH3_domain.
IPR013315. Spectrin_alpha_SH3.
[Graphical view ]
Pfami PF14604. SH3_9. 5 hits.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
PR01887. SPECTRNALPHA.
SMARTi SM00054. EFh. 2 hits.
SM00027. EH. 2 hits.
SM00326. SH3. 5 hits.
[Graphical view ]
SUPFAMi SSF50044. SSF50044. 5 hits.
PROSITEi PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 2 hits.
PS50031. EH. 2 hits.
PS50002. SH3. 5 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structural diversity and differential expression of novel human intersectin 1 isoforms."
    Kropyvko S., Gerasymchuk D., Skrypkina I., Dergai M., Dergai O., Nikolaienko O., Rynditch A., Tsyba L.
    Mol. Biol. Rep. 37:2789-2796(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiA7XZY7_HUMAN
AccessioniPrimary (citable) accession number: A7XZY7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: September 3, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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