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A7XZY7

- A7XZY7_HUMAN

UniProt

A7XZY7 - A7XZY7_HUMAN

Protein
Submitted name:

Intersectin 1 short form variant 4

Gene

ITSN1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 48 (01 Oct 2014)
      Sequence version 1 (23 Oct 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Intersectin 1 short form variant 4Imported
    Gene namesi
    Name:ITSN1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. plasma membrane Source: HPA

    PTM / Processingi

    Proteomic databases

    PRIDEiA7XZY7.

    Expressioni

    Gene expression databases

    ArrayExpressiA7XZY7.
    BgeeiA7XZY7.

    Structurei

    3D structure databases

    ProteinModelPortaliA7XZY7.
    SMRiA7XZY7. Positions 876-934, 968-1023, 1033-1177.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000010175.
    HOVERGENiHBG052159.

    Family and domain databases

    Gene3Di1.10.238.10. 2 hits.
    InterProiIPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    IPR001452. SH3_domain.
    IPR013315. Spectrin_alpha_SH3.
    [Graphical view]
    PfamiPF14604. SH3_9. 5 hits.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    PR01887. SPECTRNALPHA.
    SMARTiSM00054. EFh. 2 hits.
    SM00027. EH. 2 hits.
    SM00326. SH3. 5 hits.
    [Graphical view]
    SUPFAMiSSF50044. SSF50044. 5 hits.
    PROSITEiPS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 2 hits.
    PS50031. EH. 2 hits.
    PS50002. SH3. 5 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7XZY7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAQFPTPFGG SLDIWAITVE ERAKHDQQFH SLKPISGFIT GDQARNFFFQ     50
    SGLPQPVLAQ IWALADMNND GRMDQVEFSI AMKLIKLKLQ GYQLPSALPP 100
    VMKQQPVAIS SAPAFAAVPP LANGAPPVIQ PLPAFAHPAA TLPKSSSFSR 150
    SGPGSQLNTK LQKAQSFDVA SVPPVAEWAV PQSSRLKYRQ LFNSHDKTMS 200
    GHLTGPQART ILMQSSLPQA QLASIWNLSD IDQDGKLTAE EFILAMHLID 250
    VAMSGQPLPP VLPPEYIPPS FRRVRSGSGI SVISSTSVDQ RLPEEPVLED 300
    EQQQLEKKLP VTFEDKKREN FERGNLELEK RRQALLEQQR KEQERLAQLE 350
    RAEQERKERE RQEQERKRQL ELEKQLEKQR ELERQREEER RKEIERREAA 400
    KRELERQRQL EWERNRRQEL LNQRNKEQED IVVLKAKKKT LEFELEALND 450
    KKHQLEGKLQ DIRCRLTTQR QEIESTNKSR ELRIAEITHL QQQLQESQQM 500
    LGRLIPEKQI LNDQLKQVQQ NSLHRDSLVT LKRALEAKEL ARQHLRDQLD 550
    EVEKETRSKL QEIDIFNNQL KELREIHNKQ QLQKQKSMEA ERLKQKEQER 600
    KIIELEKQKE EAQRRAQERD KQWLEHVQQE DEHQRPRKLH EEEKLKREES 650
    VKKKDGEEKG KQEAQDKLGR LFHQHQEPAK PAVQAPWSTA EKGPLTISAQ 700
    ENVKVVYYRA LYPFESRSHD EITIQPGDIV MVKGEWVDES QTGEPGWLGG 750
    ELKGKTGWFP ANYAEKIPEN EVPAPVKPVT DSTSAPAPKL ALRETPAPLA 800
    VTSSEPSTTP NNWADFSSTW PTSTNEKPET DNWDAWAAQP SLTVPSAGQL 850
    RQRSAFTPAT ATGSSPSPVL GQGEKVEGLQ AQALYPWRAK KDNHLNFNKN 900
    DVITVLEQQD MWWFGEVQGQ KGWFPKSYVK LISGPIRKST SMDSGSSESP 950
    ASLKRVASPA AKPVVSGEEF IAMYTYESSE QGDLTFQQGD VILVTKKDGD 1000
    WWTGTVGDKA GVFPSNYVRL KDSEGSGTAG KTGSLGKKPE IAQVIASYTA 1050
    TGPEQLTLAP GQLILIRKKN PGGWWEGELQ ARGKKRQIGW FPANYVKLLS 1100
    PGTSKITPTE PPKSTALAAV CQVIGMYDYT AQNDDELAFN KGQIINVLNK 1150
    EDPDWWKGEV NGQVGLFPSN YVKLTTDMDP SQQ 1183
    Length:1,183
    Mass (Da):134,159
    Last modified:October 23, 2007 - v1
    Checksum:i8A762140D073A09C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EU107386 mRNA. Translation: ABV03351.1.
    UniGeneiHs.160324.

    Genome annotation databases

    UCSCiuc010gmi.3. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EU107386 mRNA. Translation: ABV03351.1 .
    UniGenei Hs.160324.

    3D structure databases

    ProteinModelPortali A7XZY7.
    SMRi A7XZY7. Positions 876-934, 968-1023, 1033-1177.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi A7XZY7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc010gmi.3. human.

    Phylogenomic databases

    HOGENOMi HOG000010175.
    HOVERGENi HBG052159.

    Miscellaneous databases

    NextBioi 35463564.

    Gene expression databases

    ArrayExpressi A7XZY7.
    Bgeei A7XZY7.

    Family and domain databases

    Gene3Di 1.10.238.10. 2 hits.
    InterProi IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR000261. EPS15_homology.
    IPR001452. SH3_domain.
    IPR013315. Spectrin_alpha_SH3.
    [Graphical view ]
    Pfami PF14604. SH3_9. 5 hits.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    PR01887. SPECTRNALPHA.
    SMARTi SM00054. EFh. 2 hits.
    SM00027. EH. 2 hits.
    SM00326. SH3. 5 hits.
    [Graphical view ]
    SUPFAMi SSF50044. SSF50044. 5 hits.
    PROSITEi PS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 2 hits.
    PS50031. EH. 2 hits.
    PS50002. SH3. 5 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structural diversity and differential expression of novel human intersectin 1 isoforms."
      Kropyvko S., Gerasymchuk D., Skrypkina I., Dergai M., Dergai O., Nikolaienko O., Rynditch A., Tsyba L.
      Mol. Biol. Rep. 37:2789-2796(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.

    Entry informationi

    Entry nameiA7XZY7_HUMAN
    AccessioniPrimary (citable) accession number: A7XZY7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 23, 2007
    Last sequence update: October 23, 2007
    Last modified: October 1, 2014
    This is version 48 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.