Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Large T antigen

Gene
N/A
Organism
Simian virus 40 (SV40)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi139 – 254T-ag OBDCuratedAdd BLAST116

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingCurated, HydrolaseCurated
LigandATP-bindingCurated, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Large T antigen0 Publication
OrganismiSimian virus 40 (SV40)0 Publication
Taxonomic identifieri1891767 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePolyomaviridae
Virus hostiMacaca (macaques) [TaxID: 9539]
Proteomesi
  • UP000167770 Componenti: Genome

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4B8OX-ray2.08B/C123-132[»]
SMRiA7XWN5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 75JImportedAdd BLAST64
Domaini139 – 254T-ag OBDImportedAdd BLAST116
Domaini265 – 357T-ag D1-typeImportedAdd BLAST93
Domaini400 – 560SF3 helicaseImportedAdd BLAST161

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.10.510. 1 hit.
1.10.287.110. 1 hit.
InterProiView protein in InterPro
IPR036869. DnaJ_dom_sf.
IPR001623. DnaJ_domain.
IPR014015. Helicase_SF3_DNA-vir.
IPR016392. Lg_T_Ag_polyomavir.
IPR010932. Lg_T_Ag_Polyomavir_C.
IPR027417. P-loop_NTPase.
IPR003133. T_Ag_DNA-bd.
IPR017910. Znf_lg_T-Ag_D1-typ.
IPR037102. Znf_lg_T-Ag_D1_dom_sf.
PfamiView protein in Pfam
PF06431. Polyoma_lg_T_C. 1 hit.
PF02217. T_Ag_DNA_bind. 1 hit.
PIRSFiPIRSF003368. Large_T_antigen_polyomaV. 1 hit.
SMARTiView protein in SMART
SM00271. DnaJ. 1 hit.
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS50076. DNAJ_2. 1 hit.
PS51206. SF3_HELICASE_1. 1 hit.
PS51287. T_AG_OBD. 1 hit.
PS51341. ZF_LTAG_D1. 1 hit.

Sequencei

Sequence statusi: Complete.

A7XWN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKVLNREES LQLMDLLGLE RSAWGNIPLM RKAYLKKCKE FHPDKGGDEE
60 70 80 90 100
KMKKMNTLYK KMEDGVKYAH QPDFGGFWDA TEIPTYGTDE WEQWWNAFNE
110 120 130 140 150
ENLFCSEEMP SSDDEATADS QHSTPPKKKR KVEDPKDFPS ELLSFLSHAV
160 170 180 190 200
FSNRTLACFA IYTTKEKAAL LYKKIMEKYS VTFISRHNSY NHNILFFLTP
210 220 230 240 250
HRHRVSAINN YAQKLCTFSF LICKGVNKEY LMYSALTRDP FSVIEESLPG
260 270 280 290 300
GLKEHDFNPE EAEETKQVSW KLVTEYAMET KCDDVLLLLG MYLEFQYSFE
310 320 330 340 350
MCLKCIKKEQ PSHYKYHEKH YANAAIFADS KNQKTICQQA VDTVLAKKRV
360 370 380 390 400
DSLQLTREQM LTNRFNDLLD RMDIMFGSTG SADIEEWMAG VAWLHCLLPK
410 420 430 440 450
MDSVVYDFLK CMVYNIPKKR YWLFKGPIDS GKTTLAAALL ELCGGKALNV
460 470 480 490 500
NLPLDRLNFE LGVAIDQFLV VFEDVKGTGG ESRDLPSGQG INNLDNLRDY
510 520 530 540 550
LDGSVKVNLE KKHLNKRTQI FPPGIVTMNE YSVPKTLQAR FVKQIDFRPK
560 570 580 590 600
DYLKHCLERS EFLLEKRIIQ SGIALLLMLI WYRPVAEFAQ SIQSRIVEWK
610 620 630 640 650
ERLDKEFSLS VYQKMKFNVA MGIGVLDWLR NSDDDDDDDS QENADKNEDG
660 670 680 690 700
GEKNMEDSGH ETGIDSQSQG SFQAPQPSQS SQSVHDHNQP YHICRGFTCF
710
KKPPTPPPEP ET
Length:712
Mass (Da):82,037
Last modified:October 23, 2007 - v1
Checksum:i765224F4005D5B55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF579664 Genomic DNA. Translation: ABU86079.1.

Similar proteinsi

Entry informationi

Entry nameiA7XWN5_SV40
AccessioniPrimary (citable) accession number: A7XWN5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: October 25, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureIEA:, Complete proteome0 Publication