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A7X5Z0 (A7X5Z0_STAA1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase 1 HAMAP MF_00212
EC=1.1.5.4 HAMAP MF_00212
Alternative name(s):
MQO 1 HAMAP MF_00212
Malate dehydrogenase [quinone] 1 HAMAP MF_00212
Gene names
Name:mqo1 HAMAP MF_00212
Ordered Locus Names:SAHV_2349
OrganismStaphylococcus aureus (strain Mu3 / ATCC 700698) [Complete proteome] [HAMAP]
Taxonomic identifier418127 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length511 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212 SAAS SAAS006231

Cofactor

FAD By similarity. HAMAP MF_00212 SAAS SAAS006231

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212 SAAS SAAS006231

Sequence similarities

Belongs to the MQO family. HAMAP MF_00212

Sequences

Sequence LengthMass (Da)Tools
A7X5Z0 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 2FDA265A689EB5AF

FASTA51156,986
        10         20         30         40         50         60 
MSYFSNVPLF ILKRGTVFVM TTQHSKTDVI LIGGGIMSAT LGTLLKELSP EKNIKVFEKL 

        70         80         90        100        110        120 
AQPGEESSNV WNNAGTGHSA LCELNYTKEG KDGTVDCSKA IKINEQYQIS KQFWAYLVKT 

       130        140        150        160        170        180 
GQLDNPDRFI QAVPHMSFVI GEDNVAFIKS RVATLKKSVL FEKMKLSQDE EEMKSWVPLM 

       190        200        210        220        230        240 
IEGRKSDEPI ALTYDETGTD VNFGALTAKL FENLEQRGVG IQYKQNVLDI KKQKSGAWLV 

       250        260        270        280        290        300 
KVKDLETNET TTYESDFVFI GAGGASLPLL QKTGIKQSKH IGGFPVSGLF LRCTNQEVID 

       310        320        330        340        350        360 
RHHAKVYGKA AVGAPPMSVP HLDTRFVDGK RSLLFGPFAG FSPKFLKTGS HMDLIKSVKP 

       370        380        390        400        410        420 
NNIVTMLSAG IKEMSLTKYL VSQLMLSNDE RMDDLRVFFP NAKNEDWEVI TAGQRVQVIK 

       430        440        450        460        470        480 
DTEDSKGNLQ FGTEVITSDD GTLAALLGAS PGASTAVDIM FDVLQRCYRD EFKGWEPKIK 

       490        500        510 
EMVPSFGYRL TDHEDLYHKI NEEVTKYLQV K

« Hide

References

[1]"Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance."
Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.
Antimicrob. Agents Chemother. 52:45-53(2008) [PubMed: 17954695] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009324 Genomic DNA. Translation: BAF79232.1.
RefSeqYP_001442939.1. NC_009782.1.

3D structure databases

ProteinModelPortalA7X5Z0.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7X5Z0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000004291; EBSTAP00000004190; EBSTAG00000004291.
GeneID5560469.
GenomeReviewsGene locus SAHV_2349 in contig AP009324_GR.
KEGGsaw:SAHV_2349.
PATRIC19559894. VBIStaAur127830_2413.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
GeneTreeEBGT00050000024300.
HOGENOMHBG289663.
OMAKKWVPLM.
ProtClustDBPRK05257.

Enzyme and pathway databases

BioCycSAUR418127:SAHV_2349-MONOMER.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA7X5Z0_STAA1
AccessionPrimary (citable) accession number: A7X5Z0
Entry history
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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