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A7X3F0 (RS4_STAA1) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
30S ribosomal protein S4
Gene names
Name:rpsD
Ordered Locus Names:SAHV_1705
OrganismStaphylococcus aureus (strain Mu3 / ATCC 700698) [Complete proteome] [HAMAP]
Taxonomic identifier418127 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesStaphylococcus

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit By similarity. HAMAP-Rule MF_01306

With S5 and S12 plays an important role in translational accuracy By similarity. HAMAP-Rule MF_01306

Subunit structure

Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.

Sequence similarities

Belongs to the ribosomal protein S4P family.

Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentsmall ribosomal subunit

Inferred from electronic annotation. Source: InterPro

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 20020030S ribosomal protein S4 HAMAP-Rule MF_01306
PRO_0000322337

Regions

Domain92 – 15564S4 RNA-binding

Sequences

Sequence LengthMass (Da)Tools
A7X3F0 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: E4BBB131EF37A6ED

FASTA20023,013
        10         20         30         40         50         60 
MARFRGSNWK KSRRLGISLS GTGKELEKRP YAPGQHGPNQ RKKLSEYGLQ LREKQKLRYL 

        70         80         90        100        110        120 
YGMTERQFRN TFDIAGKKFG VHGENFMILL ASRLDAVVYS LGLARTRRQA RQLVNHGHIL 

       130        140        150        160        170        180 
VDGKRVDIPS YSVKPGQTIS VREKSQKLNI IVESVEINNF VPEYLNFDAD SLTGTFVRLP 

       190        200 
ERSELPAEIN EQLIVEYYSR 

« Hide

References

[1]"Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance."
Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.
Antimicrob. Agents Chemother. 52:45-53(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Mu3 / ATCC 700698.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009324 Genomic DNA. Translation: BAF78588.1.
RefSeqYP_001442295.1. NC_009782.1.

3D structure databases

ProteinModelPortalA7X3F0.
SMRA7X3F0. Positions 43-200.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING418127.SAHV_1705.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAF78588; BAF78588; SAHV_1705.
GeneID5559030.
KEGGsaw:SAHV_1705.
PATRIC19558466. VBIStaAur127830_1751.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0522.
HOGENOMHOG000221004.
KOK02986.
OMATHGHILV.
OrthoDBEOG6N3CXM.
ProtClustDBPRK05327.

Enzyme and pathway databases

BioCycSAUR418127:GJP9-1721-MONOMER.

Family and domain databases

Gene3D1.10.1050.10. 1 hit.
3.10.290.10. 1 hit.
HAMAPMF_01306_B. Ribosomal_S4_B.
InterProIPR022801. Ribosomal_S4/S9.
IPR001912. Ribosomal_S4/S9_N.
IPR005709. Ribosomal_S4_bac-type.
IPR018079. Ribosomal_S4_CS.
IPR002942. S4_RNA-bd.
[Graphical view]
PANTHERPTHR11831. PTHR11831. 1 hit.
PfamPF00163. Ribosomal_S4. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTSM00363. S4. 1 hit.
[Graphical view]
TIGRFAMsTIGR01017. rpsD_bact. 1 hit.
PROSITEPS00632. RIBOSOMAL_S4. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRS4_STAA1
AccessionPrimary (citable) accession number: A7X3F0
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: October 23, 2007
Last modified: February 19, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries