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A7X235

- TRPF_STAA1

UniProt

A7X235 - TRPF_STAA1

Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Staphylococcus aureus (strain Mu3 / ATCC 700698)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (23 Oct 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciSAUR418127:GJP9-1377-MONOMER.
    UniPathwayiUPA00035; UER00042.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
    Short name:
    PRAIUniRule annotation
    Gene namesi
    Name:trpFUniRule annotation
    Ordered Locus Names:SAHV_1359
    OrganismiStaphylococcus aureus (strain Mu3 / ATCC 700698)
    Taxonomic identifieri418127 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000001130: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 210210N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000197120Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi418127.SAHV_1359.

    Structurei

    3D structure databases

    ProteinModelPortaliA7X235.
    SMRiA7X235. Positions 1-205.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpF family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0135.
    HOGENOMiHOG000161598.
    KOiK01817.
    OMAiPDYAGFV.
    OrthoDBiEOG6N94DF.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00135. PRAI.
    InterProiIPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00697. PRAI. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A7X235-1 [UniParc]FASTAAdd to Basket

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    MKLKFCGFTS IKDVTAASQL PIDAIGFIHY EKSKRHQTIT QIKKLASAVP    50
    NHIDKVCVMV NPDLTTIEHV LSNTSINTIQ LHGTESIDFI QEIKKKYSSI 100
    KITKALAADE NIIQNINKYK GFVDLFIIDT PSVSYGGTGQ TYDWTILKHI 150
    KDIPYLIAGG INSENIQTVN QLKLSHQGYD LASGIEVNGR KDIEKMTAIV 200
    NIVKGDRDNE 210
    Length:210
    Mass (Da):23,389
    Last modified:October 23, 2007 - v1
    Checksum:iB178BE630DF7CF24
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009324 Genomic DNA. Translation: BAF78242.1.
    RefSeqiYP_001441949.1. NC_009782.1.

    Genome annotation databases

    EnsemblBacteriaiBAF78242; BAF78242; SAHV_1359.
    GeneIDi5561049.
    KEGGisaw:SAHV_1359.
    PATRICi19557746. VBIStaAur127830_1390.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009324 Genomic DNA. Translation: BAF78242.1 .
    RefSeqi YP_001441949.1. NC_009782.1.

    3D structure databases

    ProteinModelPortali A7X235.
    SMRi A7X235. Positions 1-205.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 418127.SAHV_1359.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAF78242 ; BAF78242 ; SAHV_1359 .
    GeneIDi 5561049.
    KEGGi saw:SAHV_1359.
    PATRICi 19557746. VBIStaAur127830_1390.

    Phylogenomic databases

    eggNOGi COG0135.
    HOGENOMi HOG000161598.
    KOi K01817.
    OMAi PDYAGFV.
    OrthoDBi EOG6N94DF.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00042 .
    BioCyci SAUR418127:GJP9-1377-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00135. PRAI.
    InterProi IPR013785. Aldolase_TIM.
    IPR001240. PRAI_dom.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00697. PRAI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance."
      Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.
      Antimicrob. Agents Chemother. 52:45-53(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Mu3 / ATCC 700698.

    Entry informationi

    Entry nameiTRPF_STAA1
    AccessioniPrimary (citable) accession number: A7X235
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: October 23, 2007
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3