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A7X1A3 (A7X1A3_STAA1) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ornithine carbamoyltransferase 1 HAMAP MF_01109
Short name=OTCase 1 HAMAP MF_01109
EC=2.1.3.3 HAMAP MF_01109
Gene names
Name:argF EMBL BAF78042.1
Synonyms:argF1 HAMAP MF_01109
Ordered Locus Names:SAHV_1159
OrganismStaphylococcus aureus (strain Mu3 / ATCC 700698) [Complete proteome] [HAMAP]
Taxonomic identifier418127 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length333 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. SAAS SAAS002292 HAMAP MF_01109

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 1/3. HAMAP MF_01109

Subcellular location

Cytoplasm By similarity HAMAP MF_01109 SAAS SAAS002292.

Sequence similarities

Belongs to the ATCase/OTCase family. HAMAP MF_01109 RuleBase RU003634

Sequences

Sequence LengthMass (Da)Tools
A7X1A3 [UniParc].

Last modified October 23, 2007. Version 1.
Checksum: 1AEBBE5E81CAD27A

FASTA33337,535
        10         20         30         40         50         60 
MKNLRNRSFL TLLDFSRQEV EFLLTLSEDL KRAKYIGTEK PMLKNKNIAL LFEKDSTRTR 

        70         80         90        100        110        120 
CAFEVAAHDQ GANVTYLGPT GSQMGKKETT KDTARVLGGM YDGIEYRGFS QRTVETLAEY 

       130        140        150        160        170        180 
SGVPVWNGLT DEDHPTQVLA DFLTAKEVLK KDYADINFTY VGDGRNNVAN ALMQGAAIMG 

       190        200        210        220        230        240 
MNFHLVCPKE LNPTDELLNR CKNIAAENGG NILITDDIDQ GVKGSDVIYT DVWVSMGEPD 

       250        260        270        280        290        300 
EVWKERLELL KPYQVNKEMM DKTGNPNVIF EHCLPSFHNA DTKIGQQIFE KYGIREMEVT 

       310        320        330 
DEVFESKASV VFQEAENRMH TIKAVMVATL GEF

« Hide

References

[1]"Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance."
Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K.
Antimicrob. Agents Chemother. 52:45-53(2008) [PubMed: 17954695] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009324 Genomic DNA. Translation: BAF78042.1.
RefSeqYP_001441749.1. NC_009782.1.

3D structure databases

ProteinModelPortalA7X1A3.
SMRA7X1A3. Positions 2-333.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7X1A3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBSTAT00000004716; EBSTAP00000004615; EBSTAG00000004715.
GeneID5560622.
GenomeReviewsGene locus SAHV_1159 in contig AP009324_GR.
KEGGsaw:SAHV_1159.
PATRIC19557325. VBIStaAur127830_1181.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0078.
GeneTreeEBGT00050000023906.
HOGENOMHBG579429.
OMADFRIFAP.
ProtClustDBPRK04284.

Enzyme and pathway databases

BioCycSAUR418127:SAHV_1159-MONOMER.

Family and domain databases

HAMAPMF_01109. OTCase.
[Tree]
InterProIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
IPR002292. Orn/put_carbamltrans.
IPR024904. Orn_carbamltrans.
[Graphical view]
KOK00611.
PfamPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSPR00100. AOTCASE.
PR00102. OTCASE.
SUPFAMSSF53671. Asp/Orn_carbamoyltranf. 1 hit.
TIGRFAMsTIGR00658. Orni_carb_tr. 1 hit.
PROSITEPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7X1A3_STAA1
AccessionPrimary (citable) accession number: A7X1A3
Entry history
Integrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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