A7X0V6 (A7X0V6_STAA1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Phosphoribosylaminoimidazole carboxylase carbon dioxide-fixation chain PurK homolog EMBL BAF77940.1

Gene names

Name:	purK EMBL BAF77940.1
Ordered Locus Names:	SAHV_1057

Organism

Staphylococcus aureus (strain Mu3 / ATCC 700698) [Complete proteome] [HAMAP]

Taxonomic identifier

418127 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	374 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 ATP-grasp domain. SAAS SAAS003135

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS003135
Ligand	ATP-binding SAAS SAAS003135 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cofactor binding Inferred from electronic annotation. Source: InterPro ligase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro phosphoribosylaminoimidazole carboxylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A7X0V6 [UniParc]. Last modified October 23, 2007. Version 1. Checksum: B26CF7FDAEB426A0	FASTA	374	42,421
	10 20 30 40 50 60 MNFNKLKFGA TIGIIGGGQL GKMMAQSAQK MGYKVVVLDP SEDCPCRYVA HEFIQAKYDD 70 80 90 100 110 120 EKALNQLGQK CDVITYEFEN ISAQQLKLLC EKYNIPQGYQ AIQLLQDRLT EKETLKSAGT 130 140 150 160 170 180 KVVPFISVKE STDIDKAIET LGYPFIVKTR FGGYDGKGQV LINNEKDLQE GFKLIETSEC 190 200 210 220 230 240 VAEKYLNIKK EVSLTVTRGN NNQITFFPLQ ENEHRNQILF KTIVPARIDK TAEAKEQVNK 250 260 270 280 290 300 IIQSIHFIGT FTVEFFIDSN NQLYVNEIAP RPHNSGHYSI EACDYSQFDT HILAVTGQSL 310 320 330 340 350 360 PNSIELLKPA VMMNLLGKDL DLLENEFNEH PEWHLHIYGK SGRKDSRKMG HMTVLTNDVN 370 QTEQDMYAKF EGSN

References

[1]

"Mutated response regulator graR is responsible for phenotypic conversion of Staphylococcus aureus from heterogeneous vancomycin-intermediate resistance to vancomycin-intermediate resistance." Neoh H.-M., Cui L., Yuzawa H., Takeuchi F., Matsuo M., Hiramatsu K. Antimicrob. Agents Chemother. 52:45-53(2008) [PubMed: 17954695] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009324 Genomic DNA. Translation: BAF77940.1.
RefSeq	YP_001441647.1. NC_009782.1.
3D structure databases
ProteinModelPortal	A7X0V6.
ModBase	Search...
Protein-protein interaction databases
STRING	A7X0V6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000004401; EBSTAP00000004300; EBSTAG00000004401.
GeneID	5561333.
GenomeReviews	Gene locus SAHV_1057 in contig AP009324_GR.
KEGG	saw:SAHV_1057.
PATRIC	19557113. VBIStaAur127830_1075.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0026.
GeneTree	EBGT00050000023923.
HOGENOM	HBG516369.
OMA	GRKMGHF.
ProtClustDB	PRK06019.
Enzyme and pathway databases
BioCyc	SAUR418127:SAHV_1057-MONOMER.
Family and domain databases
InterPro	IPR005875. AIR_COase_ATPase-su. IPR011761. ATP-grasp. IPR003135. ATP-grasp_carboxylate-amine. IPR013815. ATP_grasp_subdomain_1. IPR013816. ATP_grasp_subdomain_2. IPR006140. D-isomer_2_OHA_DH_NAD-bd. IPR013817. Pre-ATP_grasp. IPR016185. PreATP-grasp-like. IPR011054. Rudment_hybrid_motif. [Graphical view]
Gene3D	G3DSA:3.30.1490.20. ATP_grasp_subdomain_1. 1 hit. G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit. G3DSA:3.40.50.20. Pre-ATP_grasp. 1 hit.
KO	K01589.
Pfam	PF02826. 2-Hacid_dh_C. 1 hit. PF02222. ATP-grasp. 1 hit. [Graphical view]
SUPFAM	SSF52440. PreATP-grasp-like. 1 hit. SSF51246. Rudmnt_hyb_motif. 1 hit.
TIGRFAMs	TIGR01161. PurK. 1 hit.
PROSITE	PS50975. ATP_GRASP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A7X0V6_STAA1

Accession

Primary (citable) accession number: A7X0V6

Entry history

Integrated into UniProtKB/TrEMBL:	October 23, 2007
Last sequence update:	October 23, 2007
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)