Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

AGAP004717-PB

Gene

1278512

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channelUniRule annotationSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
AGAP004717-PBImported
Gene namesi
Name:1278512Imported
ORF Names:AgaP_AGAP004717Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 2L

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei36 – 66HelicalSequence analysisAdd BLAST31
Transmembranei142 – 165HelicalSequence analysisAdd BLAST24
Transmembranei177 – 195HelicalSequence analysisAdd BLAST19
Transmembranei413 – 433HelicalSequence analysisAdd BLAST21
Transmembranei445 – 466HelicalSequence analysisAdd BLAST22
Transmembranei472 – 495HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiA7UUW4.

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP004717-PB.

Structurei

3D structure databases

ProteinModelPortaliA7UUW4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini143 – 198Ion_trans_2InterPro annotationAdd BLAST56
Domaini421 – 498Ion_trans_2InterPro annotationAdd BLAST78

Sequence similaritiesi

Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1418. Eukaryota.
COG1226. LUCA.
HOGENOMiHOG000008543.
InParanoidiA7UUW4.
OrthoDBiEOG091G03S1.
PhylomeDBiA7UUW4.

Family and domain databases

InterProiView protein in InterPro
IPR003280. 2pore_dom_K_chnl.
IPR013099. K_chnl_dom.
PfamiView protein in Pfam
PF07885. Ion_trans_2. 2 hits.
PRINTSiPR01333. 2POREKCHANEL.

Sequencei

Sequence statusi: Complete.

A7UUW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSRRTAPPP MQQLQPQMSI SYGEPEKKPR SKCMSFVCCM WKVFTCIFSH
60 70 80 90 100
VTLVATVVAY CFLGAFTFEH LEAENERNVK KGISSIRVNL TDAIWKMTND
110 120 130 140 150
RPVLHQQNWT SAAIMHLQSF EKEILTAMKK DGWDGNEDVD QIQWTFFGAL
160 170 180 190 200
FYSIIVITTI GYGHIAPKTY MGKISTIFYA ILGIPLMLLC LSNIGDIMAS
210 220 230 240 250
SFRFLYWRVC CYVCTREPKR SNSRRSRSSR GTVRQGSVQA AGTNLRRSVR
260 270 280 290 300
NSQRSADSGF DPYYEPGLSH SYSDTDYMDD DSPCKTPILC NKYALDDVDD
310 320 330 340 350
QDGRSTRPNP RSQSMPRQTG RYGDRLMPDR MPYYTEDNEI AENMQSVRKS
360 370 380 390 400
APQRRREPRP VPAPSPRIMS PMGFAVHRQA RHLQNVIDDN SLYDDEWDLH
410 420 430 440 450
SGELPPSSIV RPVPIWLCVF LVVSYIIAGA FMFSEWEEWS FLDSAYFCFI
460 470 480 490 500
TLTTIGFGDF VPAQGVKNDS EISIALCSLY LLFGIALLAM SFNLVQEEVI
510 520
SNVKSVARRL GILKEEELDD
Length:520
Mass (Da):59,210
Last modified:October 23, 2007 - v1
Checksum:i55B8730CEFA0C24C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008968 Genomic DNA. Translation: EDO63515.1.
RefSeqiXP_001689098.1. XM_001689046.1.

Genome annotation databases

EnsemblMetazoaiAGAP004717-RB; AGAP004717-PB; AGAP004717.
GeneIDi1278512.
KEGGiaga:AgaP_AGAP004717.
VectorBaseiAGAP004717-RB; AGAP004717-PB; AGAP004717.

Similar proteinsi

Entry informationi

Entry nameiA7UUW4_ANOGA
AccessioniPrimary (citable) accession number: A7UUW4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 23, 2007
Last sequence update: October 23, 2007
Last modified: September 27, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported