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Protein
Submitted name:

E3 ubiquitin-protein ligase Mdm2

Gene

mdm2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
E3 ubiquitin-protein ligase Mdm2Imported
Submitted name:
Mdm2Imported
Gene namesi
Name:mdm2Imported
Synonyms:MDM2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

HGNCiHGNC:6973. MDM2.

PTM / Processingi

Proteomic databases

PaxDbiA7UKX7.

Expressioni

Gene expression databases

BgeeiENSG00000135679.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000417281.

Structurei

3D structure databases

ProteinModelPortaliA7UKX7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IGXG. Eukaryota.
ENOG41125MP. LUCA.
GeneTreeiENSGT00530000063539.
HOVERGENiHBG093712.

Family and domain databases

Gene3Di1.10.245.10. 1 hit.
InterProiIPR015459. MDM2_E3_ligase.
IPR003121. SWIB_MDM2_domain.
[Graphical view]
PANTHERiPTHR13844:SF15. PTHR13844:SF15. 1 hit.
SUPFAMiSSF47592. SSF47592. 1 hit.

Sequencei

Sequence statusi: Fragment.

A7UKX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCNTNMSVPT DGAVTTSQIP ASEQETLVRP KPLLLKLLKS VGAQKDTYTM
60 70 80 90 100
KEDLDAGVSE HSGDWLDQDS VSDQFSVEFE VESLDSEDYS LSEEGQELSD
110
EDDEDYWKCT SCNEMNPP
Length:118
Mass (Da):13,133
Last modified:October 2, 2007 - v1
Checksum:i2A82DE153A1189FF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei118 – 1181Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025423 Genomic DNA. No translation available.
EU076746 mRNA. Translation: ABT17083.1.
RefSeqiNP_001138812.1. NM_001145340.2.
UniGeneiHs.484551.
Hs.733536.

Genome annotation databases

EnsembliENST00000543323; ENSP00000439238; ENSG00000135679.
GeneIDi4193.
UCSCiuc058qrp.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025423 Genomic DNA. No translation available.
EU076746 mRNA. Translation: ABT17083.1.
RefSeqiNP_001138812.1. NM_001145340.2.
UniGeneiHs.484551.
Hs.733536.

3D structure databases

ProteinModelPortaliA7UKX7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000417281.

Proteomic databases

PaxDbiA7UKX7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000543323; ENSP00000439238; ENSG00000135679.
GeneIDi4193.
UCSCiuc058qrp.1. human.

Organism-specific databases

CTDi4193.
HGNCiHGNC:6973. MDM2.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IGXG. Eukaryota.
ENOG41125MP. LUCA.
GeneTreeiENSGT00530000063539.
HOVERGENiHBG093712.

Miscellaneous databases

ChiTaRSiMDM2. human.
GenomeRNAii4193.

Gene expression databases

BgeeiENSG00000135679.

Family and domain databases

Gene3Di1.10.245.10. 1 hit.
InterProiIPR015459. MDM2_E3_ligase.
IPR003121. SWIB_MDM2_domain.
[Graphical view]
PANTHERiPTHR13844:SF15. PTHR13844:SF15. 1 hit.
SUPFAMiSSF47592. SSF47592. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA7UKX7_HUMAN
AccessioniPrimary (citable) accession number: A7UKX7
Secondary accession number(s): A0A0A6YYM9, A0A0K0K1B6, F6RKA8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: September 7, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.