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Protein
Submitted name:

Uncharacterized protein

Gene

dndA

Organism
Streptomyces lividans
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei116 – 1161N6-(pyridoxalphosphate)lysineCombined sources
Binding sitei192 – 1921N6-(pyridoxalphosphate)lysineCombined sources

GO - Molecular functioni

  1. catalytic activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Pyridoxal phosphateSAAS annotation

Enzyme and pathway databases

BRENDAi2.8.1.7. 6052.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:dndAImported
ORF Names:SLG80Imported
OrganismiStreptomyces lividansImported
Taxonomic identifieri1916 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3VAXX-ray2.40A/B19-397[»]
ProteinModelPortaliA7TUX7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni86 – 872N6-(pyridoxalphosphate)lysine bindingCombined sources
Regioni214 – 2174N6-(pyridoxalphosphate)lysine bindingCombined sources

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000192. Aminotrans_V_dom.
IPR020578. Aminotrans_V_PyrdxlP_BS.
IPR017644. Cysteine_desulfurase_DndA.
IPR016454. Cysteine_dSase_NifS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00266. Aminotran_5. 1 hit.
[Graphical view]
PIRSFiPIRSF005572. NifS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR03235. DNA_S_dndA. 1 hit.
PROSITEiPS00595. AA_TRANSFER_CLASS_5. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7TUX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTYGTCRLTL KGGLGSMVTY LDAAATTRVD QRVADIVLHW MTAEFGNAGS
60 70 80 90 100
RHEYGIRAKR GVERAREYLA STVSAEPDEL IFTSGATESN NIALLGLAPY
110 120 130 140 150
GERTGRRHII TSAIEHKAVL EPLEHLAGRG FEVDFLTPGP SGRISVEGVM
160 170 180 190 200
ERLRPDTLLV SLMHVNNETG VIQPVAELAQ QLRATPTYLH VDAAQGYGKV
210 220 230 240 250
PGDLTTPIDM ISISGHKIGA PKGVGALVTR RREEMDDERV PLEPIMFGGG
260 270 280 290 300
QERKLRPGTL PVPLIMGLAE AAKIFEAEHA QWQVAAQDLR SRLLAGLAST
310 320 330 340 350
SFQVNGDQDH VVPHILNLSF EDVDAEAFLV TLKDLVAVAT GSACTSASFT
360 370 380 390
PSHVLRAMGL PEEAASKSLR FSWTPGQATD LDVEELARGV AKLKPSY
Length:397
Mass (Da):42,821
Last modified:October 2, 2007 - v1
Checksum:i6021329924BCCBE2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF210454 Genomic DNA. Translation: ABP49156.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF210454 Genomic DNA. Translation: ABP49156.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3VAXX-ray2.40A/B19-397[»]
ProteinModelPortaliA7TUX7.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BRENDAi2.8.1.7. 6052.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000192. Aminotrans_V_dom.
IPR020578. Aminotrans_V_PyrdxlP_BS.
IPR017644. Cysteine_desulfurase_DndA.
IPR016454. Cysteine_dSase_NifS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00266. Aminotran_5. 1 hit.
[Graphical view]
PIRSFiPIRSF005572. NifS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR03235. DNA_S_dndA. 1 hit.
PROSITEiPS00595. AA_TRANSFER_CLASS_5. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 66Imported.
  2. "Analysis of a genomic island housing genes for DNA S-modification system in Streptomyces lividans 66 and its counterparts in other distantly related bacteria."
    He X., Ou H.Y., Yu Q., Zhou X., Wu J., Liang J., Zhang W., Rajakumar K., Deng Z.
    Mol. Microbiol. 65:1034-1048(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 66Imported.
  3. "Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation."
    Chen F., Zhang Z., Lin K., Qian T., Zhang Y., You D., He X., Wang Z., Liang J., Deng Z., Wu G.
    PLoS ONE 7:e36635-e36635(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 19-397 IN COMPLEX WITH N6-(PYRIDOXALPHOSPHATE)LYSINE.

Entry informationi

Entry nameiA7TUX7_STRLI
AccessioniPrimary (citable) accession number: A7TUX7
Entry historyi
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: April 1, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.