A7TMI5 (VATF_VANPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
V-type proton ATPase subunit F
Short name=V-ATPase subunit F

Alternative name(s):
V-ATPase 14 kDa subunit
Vacuolar proton pump subunit F

Gene names

Name:	VMA7
ORF Names:	Kpol_1064p61

Organism

Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus) [Complete proteome]

Taxonomic identifier

436907 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Vanderwaltozyma › Vanderwaltozyma polyspora

Protein attributes

Sequence length	119 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells By similarity.
Subunit structure	V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d) By similarity.
Sequence similarities	Belongs to the V-ATPase F subunit family.

Ontologies

Keywords
Biological process	Hydrogen ion transport Ion transport Transport
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular_component	proton-transporting V-type ATPase, V1 domain Inferred from electronic annotation. Source: InterPro
Molecular_function	proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 119	119	V-type proton ATPase subunit F		PRO_0000406051

Sequences

	Sequence		Length	Mass (Da)
	A7TMI5 [UniParc]. Last modified October 2, 2007. Version 1. Checksum: 1CE0390316E11F44	FASTA	119	13,640
	10 20 30 40 50 60 MSVDKRTLIA VIGDEDTTTG LLLAGIGQIT KETNEKNFFI YEDGKTTKEQ ILNNFINYTQ 70 80 90 100 110 ERQDIAILLI NQHIAEKIRS DIDNYTNAFP AILEIPSKDH PYDPEKDSVL KRVRRLFGE

References

[1]

"Independent sorting-out of thousands of duplicated gene pairs in two yeast species descended from a whole-genome duplication." Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H. Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 22028 / DSM 70294.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS480422 Genomic DNA. Translation: EDO16579.1.
RefSeq	XP_001644437.1. XM_001644387.1.
3D structure databases
ProteinModelPortal	A7TMI5.
ModBase	Search...
Protein-protein interaction databases
STRING	436907.A7TMI5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5544739.
KEGG	vpo:Kpol_1064p61.
Phylogenomic databases
eggNOG	COG1436.
KO	K02151.
OrthoDB	EOG44F9KR.
Family and domain databases
Gene3D	3.40.50.10580. 1 hit.
InterPro	IPR008218. ATPase_V1-cplx_f_g_su. IPR005772. ATPase_V1-cplx_fsu_euk. [Graphical view]
PANTHER	PTHR13861. PTHR13861. 1 hit.
Pfam	PF01990. ATP-synt_F. 1 hit. [Graphical view]
PIRSF	PIRSF015945. ATPase_V1_F_euk. 1 hit.
TIGRFAMs	TIGR01101. V_ATP_synt_F. 1 hit.
ProtoNet	Search...

Entry information

Entry name

VATF_VANPO

Accession

Primary (citable) accession number: A7TMI5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 8, 2011
Last sequence update:	October 2, 2007
Last modified:	May 29, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program