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A7TGW3

- A7TGW3_VANPO

UniProt

A7TGW3 - A7TGW3_VANPO

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Protein
DNA ligase
Gene
Kpol_1032p7
Organism
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:Kpol_1032p7Imported
OrganismiVanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus)
Taxonomic identifieri436907 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeVanderwaltozyma
ProteomesiUP000000267: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi436907.A7TGW3.

Structurei

3D structure databases

ProteinModelPortaliA7TGW3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1793.
KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
3.40.50.10190. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF00533. BRCT. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7TGW3-1 [UniParc]FASTAAdd to Basket

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MRNPTPILVS TNTNTNATFT SKADTNDIEE PHNFSPSPDF KWLCDELFVK    50
LDQIQFRPKE LNGSKPKYIE YYDIINNFID IWRRTVGNDI YPALILTIPY 100
RDRRMYNIKE SKLIRIVCDY LKLPKNSETE RRLMRWKHRA DRNVRLSTFC 150
VEEIKKRKGE PREKIKITID KLNECLDNLV LERGYKGSKS QKISESETFK 200
FCFENMTYVE LKYFFDILLK DKIVGGLEHK FLNCWHPDAQ DYLSVVSDLK 250
IVSSKLWNPE FRLKYDDLTI NIDHAFTPET AKRLTYSYDT IARRLKNDFF 300
IEEKMDGERI QLHYMNYGAK LKFLSRRGLD YSYLYGDNRN NGAIGRYLNF 350
HKDVKECILD GEMVTYDSVK NCILPFGLVK SSAMQSLSVS DIEPDGYHPL 400
YMAFDLVYLN GSSLSTLPLH QRKNYLDKLL IPCPDFVEIL PALHCNDSSL 450
IKSSLEKAIE LGSEGIILKR FDSQYLVAKR SDDWIKIKPE YLEQFGENMD 500
LIVIGRDPGK KDSLMCGLIL TGDNEPEEIT SLDSNPTDTA ESFLKPDKRK 550
IISFCNIANG ISQKEFRDID RYTFGHWIKF DDELPPQDLF EFGTKHPIEW 600
IYPEHSVVLE IKARSLETNE SARIKYGTGS TLFGGYCRQI RYDKDWVSCF 650
TYNEFMESRN LKNALVNYPD NKNLIGRKKR PKKRMFNSLT EIFENTKDAP 700
DESNVIFRGL HFYVISDYID ETDGSRLSKS DLCNLVLEHN GKLVHNPISR 750
IDILNRLRII SMKYTRETTS LIERGYDIIH PQWILDCISN RKLVRLLPSH 800
CFNVSSSLME VTKTRVDRYG DSYETSLTEK DFEILINRQV LKSESADKRI 850
TEGENHLKIP ILLFCNRRFF IPETLPSTPI YELKSKVELY GGKLVNKISD 900
CNVIVFTNTH TENRKEVMKK IRRALVCLDP NSMQVPVLPR IVDANWIDAC 950
ISECVQVPEE DYPAV 965
Length:965
Mass (Da):112,453
Last modified:October 2, 2007 - v1
Checksum:i18173392179317B9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS480389 Genomic DNA. Translation: EDO18415.1.
RefSeqiXP_001646273.1. XM_001646223.1.

Genome annotation databases

GeneIDi5546698.
KEGGivpo:Kpol_1032p7.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS480389 Genomic DNA. Translation: EDO18415.1 .
RefSeqi XP_001646273.1. XM_001646223.1.

3D structure databases

ProteinModelPortali A7TGW3.
ModBasei Search...

Protein-protein interaction databases

STRINGi 436907.A7TGW3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5546698.
KEGGi vpo:Kpol_1032p7.

Phylogenomic databases

eggNOGi COG1793.
KOi K10777.
OrthoDBi EOG7QC84G.

Family and domain databases

Gene3Di 2.40.50.140. 1 hit.
3.40.50.10190. 1 hit.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF00533. BRCT. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 2 hits.
[Graphical view ]
SUPFAMi SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Independent sorting-out of thousands of duplicated gene pairs in two yeast species descended from a whole-genome duplication."
    Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.
    Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 22028 / DSM 70294.

Entry informationi

Entry nameiA7TGW3_VANPO
AccessioniPrimary (citable) accession number: A7TGW3
Entry historyi
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: November 13, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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