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A7TFW4 (EIF3G_VANPO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Eukaryotic translation initiation factor 3 subunit G

Short name=eIF3g
Alternative name(s):
Eukaryotic translation initiation factor 3 RNA-binding subunit
Short name=eIF-3 RNA-binding subunit
Translation initiation factor eIF3 p33 subunit homolog
Short name=eIF3 p33 homolog
Gene names
Name:TIF35
ORF Names:Kpol_1023p95
OrganismVanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus) [Complete proteome]
Taxonomic identifier436907 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeVanderwaltozyma

Protein attributes

Sequence length274 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. This subunit can bind 18S rRNA By similarity. HAMAP-Rule MF_03006

Subunit structure

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_03006.

Sequence similarities

Belongs to the eIF-3 subunit G family.

Contains 1 RRM (RNA recognition motif) domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 274274Eukaryotic translation initiation factor 3 subunit G HAMAP-Rule MF_03006
PRO_0000366896

Regions

Domain191 – 27080RRM

Amino acid modifications

Modified residue1681Phosphoserine By similarity

Sequences

Sequence LengthMass (Da)Tools
A7TFW4 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: F772DE449C35E5BB

FASTA27430,640
        10         20         30         40         50         60 
MTEAMNSEVI NNPDGTKTII TYRVENGQKF KITQKVREVH VSEKVHKAVA SRKQWAKYGE 

        70         80         90        100        110        120 
ERNAPPGPNH STTQLGEEVY LRLSRNWKQK EEEETEKAKI KSDGIISCRL CGNAHYTMNC 

       130        140        150        160        170        180 
PFKSIMSDIA ALEDPNAPIE VGSNAVEAPV ETASSAAAVA SGKYVPPSRR AGAKDPSSDA 

       190        200        210        220        230        240 
YRDSRERDDM ATLKITQLNE NADETTLREE LLFPFGNIPR VVVVRNRETG RSRGLAFVTF 

       250        260        270 
SSEEVAEKAR RLLNGRGFMN LILQVDWSKP KEKE 

« Hide

References

[1]"Independent sorting-out of thousands of duplicated gene pairs in two yeast species descended from a whole-genome duplication."
Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.
Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 22028 / DSM 70294.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS480384 Genomic DNA. Translation: EDO18922.1.
RefSeqXP_001646780.1. XM_001646730.1.

3D structure databases

ProteinModelPortalA7TFW4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING436907.A7TFW4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5547242.
KEGGvpo:Kpol_1023p95.

Phylogenomic databases

eggNOGCOG0724.
KOK03248.
OrthoDBEOG7J44J3.

Family and domain databases

Gene3D3.30.70.330. 1 hit.
HAMAPMF_03006. eIF3g.
InterProIPR017334. eIF3_g.
IPR024675. eIF3g_N.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PANTHERPTHR10352. PTHR10352. 1 hit.
PfamPF12353. eIF3g. 1 hit.
PF00076. RRM_1. 1 hit.
[Graphical view]
PIRSFPIRSF037949. Transl_init_eIF-3_RNA-bind. 1 hit.
SMARTSM00360. RRM. 1 hit.
[Graphical view]
PROSITEPS50102. RRM. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEIF3G_VANPO
AccessionPrimary (citable) accession number: A7TFW4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: October 2, 2007
Last modified: February 19, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries