A7T5I4 (A7T5I4_NEMVE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
6-phosphogluconate dehydrogenase, decarboxylating RuleBase RU000485
EC=1.1.1.44 RuleBase RU000485

Gene names

ORF Names:

v1g146786

Organism

Nematostella vectensis (Starlet sea anemone)

Taxonomic identifier

45351 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Cnidaria › Anthozoa › Hexacorallia › Actiniaria › Edwardsiidae › Nematostella

Protein attributes

Sequence length	336 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH. RuleBase RU000485
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3. RuleBase RU004281
Sequence similarities	Belongs to the 6-phosphogluconate dehydrogenase family. RuleBase RU000485

Ontologies

Keywords
Biological process	Pentose shunt RuleBase RU004281
Ligand	NADP RuleBase RU000485
Molecular function	Oxidoreductase RuleBase RU000485
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro phosphogluconate dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL EDO28780.1

Sequences

	Sequence		Length	Mass (Da)
	A7T5I4 [UniParc]. Last modified October 2, 2007. Version 1. Checksum: 39D9CB31A8055D4D	FASTA	336	36,892
	10 20 30 40 50 60 QRRCKALEER GLLFVGSGVS GGEEGARYGP SLMPGGSEKA WPHIKPIFQA IAAKAGNDPC 70 80 90 100 110 120 CDWVGGDGSG HFVKMVHNGI EYGDMQLCCE AYHLMKDALG MTSDEISQVF DEWNKGELDS 130 140 150 160 170 180 FLIEITKNIM AYKDADGSPL VEKIRDSAGQ KGTGKWTAIS ALEYGMPVTL IGESVFARCL 190 200 210 220 230 240 SSLQAERVHA STHLKGPAST KFTGDKKEFV EHIRKALYAS KIVSYAQGFM LMREAAKVFN 250 260 270 280 290 300 WKLNYGGIAL MWRGGCIIRS RFLGNIKDAF NKNPNLDNLL LDDFFKDAIH KCQDSWRKTI 310 320 330 ATAVTLGIPT PAFSTALAFY DGYRSARLPA NLIQVG

References

[1]

"Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization." Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A., Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J., Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R., Technau U., Martindale M.Q., Rokhsar D.S. Science 317:86-94(2007) [PubMed: 17615350] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CH2 X CH6.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS471194 Genomic DNA. Translation: EDO28780.1.
RefSeq	XP_001620880.1. XM_001620830.1.
3D structure databases
ProteinModelPortal	A7T5I4.
ModBase	Search...
Protein-protein interaction databases
STRING	A7T5I4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	NEMVEDRAFT_v1g146786-RA; NEMVEDRAFT_v1g146786-PA; NEMVEDRAFT_v1g146786.
GeneID	5499252.
KEGG	nve:NEMVE_v1g146786.
Phylogenomic databases
OMA	SNRRTKY.
PhylomeDB	A7T5I4.
Family and domain databases
InterPro	IPR008927. 6-PGluconate_DH_C-like. IPR006114. 6PGDH_C. IPR006113. 6PGDH_decarbox. IPR006115. 6PGDH_NADP-bd. IPR006184. 6PGdom_BS. IPR013328. DH_multihelical. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
Pfam	PF00393. 6PGD. 1 hit. PF03446. NAD_binding_2. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR00873. Gnd. 1 hit.
PROSITE	PS00461. 6PGD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A7T5I4_NEMVE

Accession

Primary (citable) accession number: A7T5I4

Entry history

Integrated into UniProtKB/TrEMBL:	October 2, 2007
Last sequence update:	October 2, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)