A7SXZ6 (OSGEP_NEMVE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein osgep

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein osgep

Gene names

Name:	osgep
ORF Names:	v1g194666

Organism

Nematostella vectensis (Starlet sea anemone)

Taxonomic identifier

45351 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Cnidaria › Anthozoa › Hexacorallia › Actiniaria › Edwardsiidae › Nematostella

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Ligand	Iron Metal-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 335	335	Probable tRNA threonylcarbamoyladenosine biosynthesis protein osgep		PRO_0000331476
Sites
	Metal binding	109	1	Iron By similarity
	Metal binding	113	1	Iron By similarity
	Metal binding	130	1	Iron By similarity
	Metal binding	294	1	Iron By similarity

Sequences

	Sequence		Length	Mass (Da)
	A7SXZ6 [UniParc]. Last modified October 2, 2007. Version 1. Checksum: 4DB1D7DE0E07EA3D	FASTA	335	36,988
	10 20 30 40 50 60 MPTVIGFEGS ANKLGIGIIR DGVVLSNPRH TYITPPGQGF MPRDTAKHHQ EHAIDILRRA 70 80 90 100 110 120 LDEAQIRPQD IDCICYTKGP GMGAPLVAVA VVARTVAQLW KKPIIGVNHC IGHIEMGRLI 130 140 150 160 170 180 TGANNPTVLY VSGGNTQVIA YLQKRYRIFG ETIDIAVGNC LDRFARVLKL SNDPSPGYNI 190 200 210 220 230 240 EQMAKKGKKL IELPYTVKGM DVSFSGILSY IECMAHKLLS SEECTPEDLC FSLQETVFAM 250 260 270 280 290 300 LVETTERAMA HCGSNEVLIV GGVGCNKRLQ EMMDVMAKER GAKLYATDER FCIDNGAMIA 310 320 330 QAGWEMFQTG SVTPLEQTTC TQRFRTDEVE VTWRD

References

[1]

"Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization." Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A., Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J., Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R., Technau U., Martindale M.Q., Rokhsar D.S. Science 317:86-94(2007) [PubMed: 17615350] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CH2 X CH6.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS469901 Genomic DNA. Translation: EDO31427.1.
RefSeq	XP_001623527.1. XM_001623477.1.
3D structure databases
ProteinModelPortal	A7SXZ6.
ModBase	Search...
Protein-protein interaction databases
STRING	A7SXZ6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	NEMVEDRAFT_v1g194666-RA; NEMVEDRAFT_v1g194666-PA; NEMVEDRAFT_v1g194666.
GeneID	5502327.
KEGG	nve:NEMVE_v1g194666.
Phylogenomic databases
OMA	RRTYITP.
PhylomeDB	A7SXZ6.
Family and domain databases
InterPro	IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. IPR016038. Thiolase-like_subgr. [Graphical view]
Gene3D	G3DSA:3.40.47.10. Thiolase-like_subgr. 1 hit.
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

OSGEP_NEMVE

Accession

Primary (citable) accession number: A7SXZ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 29, 2008
Last sequence update:	October 2, 2007
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)