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A7SE93

- A7SE93_NEMVE

UniProt

A7SE93 - A7SE93_NEMVE

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Protein

DNA ligase

Gene

v1g230001

Organism
Nematostella vectensis (Starlet sea anemone)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:v1g230001Imported
OrganismiNematostella vectensis (Starlet sea anemone)Imported
Taxonomic identifieri45351 [NCBI]
Taxonomic lineageiEukaryotaMetazoaCnidariaAnthozoaHexacoralliaActiniariaEdwardsiidaeNematostella
ProteomesiUP000001593: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi45351.JGI230001.

Structurei

3D structure databases

ProteinModelPortaliA7SE93.
SMRiA7SE93. Positions 1-110.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000007653.
InParanoidiA7SE93.
KOiK10776.
OMAiLFSEMKH.
OrthoDBiEOG7BKCT2.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.30.1740.10. 1 hit.
3.40.50.10190. 1 hit.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
IPR001510. Znf_PARP.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF00645. zf-PARP. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
PS00347. PARP_ZN_FINGER_1. 1 hit.
PS50064. PARP_ZN_FINGER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7SE93-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEDLKSFLV EYAPQGRAKC KGCKEQIEKS SARIAKLAPN PFSEDGGLMK
60 70 80 90 100
QWYHVKCIFD SFSRARATTK KIEDAEDLDG FVDMKQDDQN TIKQLISGLS
110 120 130 140 150
GKKVSPGKKA SQKPTSSPGQ KKVQGTLTFS PTNTSVRPLM TVAGSSKGTV
160 170 180 190 200
SLLRIKRIAT YLVSQAGRIQ IVTCSNHTAQ IFRRAVAVLR ASDNLSASKA
210 220 230 240 250
GAESSKDDAF REFRKLCVQL AEEPSYNAKT RLVANLLKKG PSGSGFQGDT
260 270 280 290 300
TLWVKMLLPA INKRVYNLQS KQLVKLFSQI FCCNYDDMVT HLEEGGDVSE
310 320 330 340 350
TISNFFTNSI ICKPAKKSNL TLQQVDSFLD RLKLLTKEDD QQRELCSITQ
360 370 380 390 400
RCTSNDLKYI IRLIKHDLRM NAGAKHVLEA IDPDAYKAFQ ASNDLEDVVK
410 420 430 440 450
RCLEKHASSG NDRVPGMSKK LSIRASLMTP VKPMLAEACK TFSYAIKKCP
460 470 480 490 500
KGMLAEIKYD GERVQVHKSG SKFEFFSRSL KPVLPHKVSA FRDFLPKACP
510 520 530 540 550
HGNNLILDCE VLLVDNKTSL PLPFGTLGIH KKSAFKDANV CLFIFDCLQF
560 570 580 590 600
NEENVMRKSM TERRKILEEN VTVIPNRIML SETTFVKDEK KLSQLMARAM
610 620 630 640 650
RDGLEGLVLK DVTGQYEPGK RHWLKMKKDY LEEGSMADTA DLVVLGAYYG
660 670 680 690 700
TGNKGGLMSV FLMGVFNPRI KKWCTVAKCG NGHDDKTLDK LNRELKVKKI
710 720 730 740 750
SKDPNRVPVW LEVHRSLIPD FVVDDPKKAP VWEITGAEFS KSTTHTADGI
760 770 780 790 800
SIRFPRVTRI RDDKDWETAT DLDLLKPVVH LHAPLWPDNH RMRMYNTKNE
810 820 830 840 850
DEPMDSDETV DNDDVTERKS SAKRKANQIE NDKDEASDRK ELPNVFSGLQ
860 870 880 890
VYVPDTIKDF NKLRRYIIAS RYDGDVVTDK STATHIIANS KVTP
Length:894
Mass (Da):100,451
Last modified:October 2, 2007 - v1
Checksum:iA25E5D5D3781C802
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS469635 Genomic DNA. Translation: EDO37995.1.
RefSeqiXP_001630058.1. XM_001630008.1.

Genome annotation databases

EnsemblMetazoaiEDO37995; EDO37995; NEMVEDRAFT_v1g230001.
GeneIDi5509532.
KEGGinve:NEMVE_v1g230001.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS469635 Genomic DNA. Translation: EDO37995.1 .
RefSeqi XP_001630058.1. XM_001630008.1.

3D structure databases

ProteinModelPortali A7SE93.
SMRi A7SE93. Positions 1-110.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 45351.JGI230001.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai EDO37995 ; EDO37995 ; NEMVEDRAFT_v1g230001 .
GeneIDi 5509532.
KEGGi nve:NEMVE_v1g230001.

Phylogenomic databases

eggNOGi COG1793.
HOGENOMi HOG000007653.
InParanoidi A7SE93.
KOi K10776.
OMAi LFSEMKH.
OrthoDBi EOG7BKCT2.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.30.1740.10. 1 hit.
3.40.50.10190. 1 hit.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
IPR001510. Znf_PARP.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
PF00645. zf-PARP. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
PS00347. PARP_ZN_FINGER_1. 1 hit.
PS50064. PARP_ZN_FINGER_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CH2 X CH6Imported.

Entry informationi

Entry nameiA7SE93_NEMVE
AccessioniPrimary (citable) accession number: A7SE93
Entry historyi
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: October 29, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3