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A7SE93

- A7SE93_NEMVE

UniProt

A7SE93 - A7SE93_NEMVE

Protein

DNA ligase

Gene

v1g230001

Organism
Nematostella vectensis (Starlet sea anemone)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 49 (01 Oct 2014)
      Sequence version 1 (02 Oct 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC
    4. zinc ion binding Source: InterPro

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:v1g230001Imported
    OrganismiNematostella vectensis (Starlet sea anemone)Imported
    Taxonomic identifieri45351 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaCnidariaAnthozoaHexacoralliaActiniariaEdwardsiidaeNematostella
    ProteomesiUP000001593: Unassembled WGS sequence

    Interactioni

    Protein-protein interaction databases

    STRINGi45351.JGI230001.

    Structurei

    3D structure databases

    ProteinModelPortaliA7SE93.
    SMRiA7SE93. Positions 1-110.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1793.
    HOGENOMiHOG000007653.
    KOiK10776.
    OMAiLFSEMKH.
    OrthoDBiEOG7BKCT2.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1740.10. 1 hit.
    3.40.50.10190. 1 hit.
    InterProiIPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    IPR001510. Znf_PARP.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    PF00645. zf-PARP. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    PS00347. PARP_ZN_FINGER_1. 1 hit.
    PS50064. PARP_ZN_FINGER_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7SE93-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEDLKSFLV EYAPQGRAKC KGCKEQIEKS SARIAKLAPN PFSEDGGLMK    50
    QWYHVKCIFD SFSRARATTK KIEDAEDLDG FVDMKQDDQN TIKQLISGLS 100
    GKKVSPGKKA SQKPTSSPGQ KKVQGTLTFS PTNTSVRPLM TVAGSSKGTV 150
    SLLRIKRIAT YLVSQAGRIQ IVTCSNHTAQ IFRRAVAVLR ASDNLSASKA 200
    GAESSKDDAF REFRKLCVQL AEEPSYNAKT RLVANLLKKG PSGSGFQGDT 250
    TLWVKMLLPA INKRVYNLQS KQLVKLFSQI FCCNYDDMVT HLEEGGDVSE 300
    TISNFFTNSI ICKPAKKSNL TLQQVDSFLD RLKLLTKEDD QQRELCSITQ 350
    RCTSNDLKYI IRLIKHDLRM NAGAKHVLEA IDPDAYKAFQ ASNDLEDVVK 400
    RCLEKHASSG NDRVPGMSKK LSIRASLMTP VKPMLAEACK TFSYAIKKCP 450
    KGMLAEIKYD GERVQVHKSG SKFEFFSRSL KPVLPHKVSA FRDFLPKACP 500
    HGNNLILDCE VLLVDNKTSL PLPFGTLGIH KKSAFKDANV CLFIFDCLQF 550
    NEENVMRKSM TERRKILEEN VTVIPNRIML SETTFVKDEK KLSQLMARAM 600
    RDGLEGLVLK DVTGQYEPGK RHWLKMKKDY LEEGSMADTA DLVVLGAYYG 650
    TGNKGGLMSV FLMGVFNPRI KKWCTVAKCG NGHDDKTLDK LNRELKVKKI 700
    SKDPNRVPVW LEVHRSLIPD FVVDDPKKAP VWEITGAEFS KSTTHTADGI 750
    SIRFPRVTRI RDDKDWETAT DLDLLKPVVH LHAPLWPDNH RMRMYNTKNE 800
    DEPMDSDETV DNDDVTERKS SAKRKANQIE NDKDEASDRK ELPNVFSGLQ 850
    VYVPDTIKDF NKLRRYIIAS RYDGDVVTDK STATHIIANS KVTP 894
    Length:894
    Mass (Da):100,451
    Last modified:October 2, 2007 - v1
    Checksum:iA25E5D5D3781C802
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS469635 Genomic DNA. Translation: EDO37995.1.
    RefSeqiXP_001630058.1. XM_001630008.1.

    Genome annotation databases

    EnsemblMetazoaiEDO37995; EDO37995; NEMVEDRAFT_v1g230001.
    GeneIDi5509532.
    KEGGinve:NEMVE_v1g230001.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS469635 Genomic DNA. Translation: EDO37995.1 .
    RefSeqi XP_001630058.1. XM_001630008.1.

    3D structure databases

    ProteinModelPortali A7SE93.
    SMRi A7SE93. Positions 1-110.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 45351.JGI230001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai EDO37995 ; EDO37995 ; NEMVEDRAFT_v1g230001 .
    GeneIDi 5509532.
    KEGGi nve:NEMVE_v1g230001.

    Phylogenomic databases

    eggNOGi COG1793.
    HOGENOMi HOG000007653.
    KOi K10776.
    OMAi LFSEMKH.
    OrthoDBi EOG7BKCT2.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    3.30.1740.10. 1 hit.
    3.40.50.10190. 1 hit.
    InterProi IPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    IPR001510. Znf_PARP.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    PF00645. zf-PARP. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    PS00347. PARP_ZN_FINGER_1. 1 hit.
    PS50064. PARP_ZN_FINGER_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CH2 X CH6Imported.

    Entry informationi

    Entry nameiA7SE93_NEMVE
    AccessioniPrimary (citable) accession number: A7SE93
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 2, 2007
    Last sequence update: October 2, 2007
    Last modified: October 1, 2014
    This is version 49 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3