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A7S8B0

- A7S8B0_NEMVE

UniProt

A7S8B0 - A7S8B0_NEMVE

Protein

Thymidine kinase

Gene

v1g243527

Organism
Nematostella vectensis (Starlet sea anemone)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (02 Oct 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. thymidine kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotation, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    ORF Names:v1g243527Imported
    OrganismiNematostella vectensis (Starlet sea anemone)Imported
    Taxonomic identifieri45351 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaCnidariaAnthozoaHexacoralliaActiniariaEdwardsiidaeNematostella
    ProteomesiUP000001593: Unassembled WGS sequence

    Interactioni

    Protein-protein interaction databases

    STRINGi45351.JGI243527.

    Structurei

    3D structure databases

    ProteinModelPortaliA7S8B0.
    SMRiA7S8B0. Positions 23-194.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1435.
    HOGENOMiHOG000076390.
    KOiK00857.
    OMAiQILQCSP.
    OrthoDBiEOG7MSMPX.

    Family and domain databases

    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7S8B0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MALVTIPGLQ HLHRHHSISE CPGQIQVIFG PMFSGKTTEL LRRIKRYQVA    50
    NHKCLLIKYA KDIRYDEEGV ATHDRQILRA TPCTVLEDLK NKAINHSVIG 100
    IDEGQFFPDI VEFSEEMASE GKTIIIAALD GTFQRKAFGN ILHLVPLAES 150
    VVKLSAVCMN CFKDASFTKR LGYDKRVEVI GGADKYMSVC RECYNLAEVQ 200
    ELLSKHSKFQ TH 212
    Length:212
    Mass (Da):23,920
    Last modified:October 2, 2007 - v1
    Checksum:i9E1AE970E6ABD1C7
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS469597 Genomic DNA. Translation: EDO40073.1.
    RefSeqiXP_001632136.1. XM_001632086.1.
    UniGeneiNve.8375.

    Genome annotation databases

    EnsemblMetazoaiEDO40073; EDO40073; NEMVEDRAFT_v1g243527.
    GeneIDi5511757.
    KEGGinve:NEMVE_v1g243527.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS469597 Genomic DNA. Translation: EDO40073.1 .
    RefSeqi XP_001632136.1. XM_001632086.1.
    UniGenei Nve.8375.

    3D structure databases

    ProteinModelPortali A7S8B0.
    SMRi A7S8B0. Positions 23-194.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 45351.JGI243527.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai EDO40073 ; EDO40073 ; NEMVEDRAFT_v1g243527 .
    GeneIDi 5511757.
    KEGGi nve:NEMVE_v1g243527.

    Phylogenomic databases

    eggNOGi COG1435.
    HOGENOMi HOG000076390.
    KOi K00857.
    OMAi QILQCSP.
    OrthoDBi EOG7MSMPX.

    Family and domain databases

    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020633. Thymidine_kinase_CS.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CH2 X CH6Imported.

    Entry informationi

    Entry nameiA7S8B0_NEMVE
    AccessioniPrimary (citable) accession number: A7S8B0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 2, 2007
    Last sequence update: October 2, 2007
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3