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A7S8B0

- A7S8B0_NEMVE

UniProt

A7S8B0 - A7S8B0_NEMVE

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Protein

Thymidine kinase

Gene
v1g243527
Organism
Nematostella vectensis (Starlet sea anemone)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. thymidine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
ORF Names:v1g243527Imported
OrganismiNematostella vectensis (Starlet sea anemone)
Taxonomic identifieri45351 [NCBI]
Taxonomic lineageiEukaryotaMetazoaCnidariaAnthozoaHexacoralliaActiniariaEdwardsiidaeNematostella
ProteomesiUP000001593: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi45351.JGI243527.

Structurei

3D structure databases

ProteinModelPortaliA7S8B0.
SMRiA7S8B0. Positions 23-194.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1435.
HOGENOMiHOG000076390.
KOiK00857.
OMAiQILQCSP.
OrthoDBiEOG7MSMPX.

Family and domain databases

InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7S8B0-1 [UniParc]FASTAAdd to Basket

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MALVTIPGLQ HLHRHHSISE CPGQIQVIFG PMFSGKTTEL LRRIKRYQVA    50
NHKCLLIKYA KDIRYDEEGV ATHDRQILRA TPCTVLEDLK NKAINHSVIG 100
IDEGQFFPDI VEFSEEMASE GKTIIIAALD GTFQRKAFGN ILHLVPLAES 150
VVKLSAVCMN CFKDASFTKR LGYDKRVEVI GGADKYMSVC RECYNLAEVQ 200
ELLSKHSKFQ TH 212
Length:212
Mass (Da):23,920
Last modified:October 2, 2007 - v1
Checksum:i9E1AE970E6ABD1C7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS469597 Genomic DNA. Translation: EDO40073.1.
RefSeqiXP_001632136.1. XM_001632086.1.
UniGeneiNve.8375.

Genome annotation databases

EnsemblMetazoaiEDO40073; EDO40073; NEMVEDRAFT_v1g243527.
GeneIDi5511757.
KEGGinve:NEMVE_v1g243527.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS469597 Genomic DNA. Translation: EDO40073.1 .
RefSeqi XP_001632136.1. XM_001632086.1.
UniGenei Nve.8375.

3D structure databases

ProteinModelPortali A7S8B0.
SMRi A7S8B0. Positions 23-194.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 45351.JGI243527.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai EDO40073 ; EDO40073 ; NEMVEDRAFT_v1g243527 .
GeneIDi 5511757.
KEGGi nve:NEMVE_v1g243527.

Phylogenomic databases

eggNOGi COG1435.
HOGENOMi HOG000076390.
KOi K00857.
OMAi QILQCSP.
OrthoDBi EOG7MSMPX.

Family and domain databases

InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CH2 X CH6.

Entry informationi

Entry nameiA7S8B0_NEMVE
AccessioniPrimary (citable) accession number: A7S8B0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: June 11, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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