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A7S8B0 (A7S8B0_NEMVE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Thymidine kinase RuleBase RU000544

EC=2.7.1.21 RuleBase RU000544
Gene names
ORF Names:v1g243527 EMBL EDO40073.1
OrganismNematostella vectensis (Starlet sea anemone) [Reference proteome]
Taxonomic identifier45351 [NCBI]
Taxonomic lineageEukaryotaMetazoaCnidariaAnthozoaHexacoralliaActiniariaEdwardsiidaeNematostella

Protein attributes

Sequence length212 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate.

Sequence similarities

Belongs to the thymidine kinase family. RuleBase RU004165

Ontologies

Keywords
   Biological processDNA synthesis RuleBase RU000544
   LigandATP-binding RuleBase RU000544
Nucleotide-binding
   Molecular functionKinase RuleBase RU000544
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA replication

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

thymidine kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A7S8B0 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: 9E1AE970E6ABD1C7

FASTA21223,920
        10         20         30         40         50         60 
MALVTIPGLQ HLHRHHSISE CPGQIQVIFG PMFSGKTTEL LRRIKRYQVA NHKCLLIKYA 

        70         80         90        100        110        120 
KDIRYDEEGV ATHDRQILRA TPCTVLEDLK NKAINHSVIG IDEGQFFPDI VEFSEEMASE 

       130        140        150        160        170        180 
GKTIIIAALD GTFQRKAFGN ILHLVPLAES VVKLSAVCMN CFKDASFTKR LGYDKRVEVI 

       190        200        210 
GGADKYMSVC RECYNLAEVQ ELLSKHSKFQ TH 

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References

[1]"Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization."
Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A., Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J., Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R., Technau U., Martindale M.Q., Rokhsar D.S.
Science 317:86-94(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CH2 X CH6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DS469597 Genomic DNA. Translation: EDO40073.1.
RefSeqXP_001632136.1. XM_001632086.1.
UniGeneNve.8375.

3D structure databases

ProteinModelPortalA7S8B0.
SMRA7S8B0. Positions 23-194.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING45351.JGI243527.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaNEMVEDRAFT_v1g243527-RA; NEMVEDRAFT_v1g243527-PA; NEMVEDRAFT_v1g243527.
GeneID5511757.
KEGGnve:NEMVE_v1g243527.

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076390.
KOK00857.
OMAVRRFQLA.
OrthoDBEOG7MSMPX.

Family and domain databases

InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA7S8B0_NEMVE
AccessionPrimary (citable) accession number: A7S8B0
Entry history
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: April 16, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)