A7RHF7 (A7RHF7_NEMVE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Eukaryotic translation initiation factor 6 HAMAP-Rule MF_03132
Short name=eIF-6 HAMAP-Rule MF_03132

Gene names

Name:	EIF6 HAMAP-Rule MF_03132
ORF Names:	v1g177965

Organism

Nematostella vectensis (Starlet sea anemone) [Reference proteome]

Taxonomic identifier

45351 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Cnidaria › Anthozoa › Hexacorallia › Actiniaria › Edwardsiidae › Nematostella

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis By similarity. HAMAP-Rule MF_03132
Subunit structure	Monomer. Associates with the 60S ribosomal subunit By similarity. HAMAP-Rule MF_03132
Subcellular location	Cytoplasm. Nucleus › nucleolus. Note: Shuttles between cytoplasm and nucleus/nucleolus By similarity. HAMAP-Rule MF_03132
Sequence similarities	Belongs to the eIF-6 family. HAMAP-Rule MF_03132

Ontologies

Keywords
Biological process	Protein biosynthesis Ribosome biogenesis HAMAP-Rule MF_03132
Cellular component	Cytoplasm HAMAP-Rule MF_03132 Nucleus HAMAP-Rule MF_03132
Molecular function	Initiation factor HAMAP-Rule MF_03132
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	mature ribosome assembly Inferred from electronic annotation. Source: HAMAP ribosomal large subunit biogenesis Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell nucleolus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ribosomal large subunit binding Inferred from electronic annotation. Source: HAMAP ribosome binding Inferred from electronic annotation. Source: InterPro translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A7RHF7 [UniParc]. Last modified October 2, 2007. Version 1. Checksum: 3114A0397C8F370F	FASTA	236	25,450
	10 20 30 40 50 60 MAVRAQFENS NEVGVFSKLT NAYCLVAIGA TENFYSVFES ELSDVIPVVR TSIAGCRIIG 70 80 90 100 110 120 RLCVGNRHGL LVPSTTTDQE LQYIRNALPD QVKIQRVEER LSALGNVIAC NDYVALTHLD 130 140 150 160 170 180 LDMETQEILA DVLKVEVFRQ SLASNVLVGS YCALSNQGGL VHPRTSIEDQ DELSSLLQVP 190 200 210 220 230 LVAGTVNRGS DVIGAGLVVN DWSAFCGSDT TSTELSVIES VFKIGDAQQS SIGDNH

References

[1]

"Sea anemone genome reveals ancestral eumetazoan gene repertoire and genomic organization." Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A., Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J., Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R., Technau U., Martindale M.Q., Rokhsar D.S. Science 317:86-94(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CH2 X CH6.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS469510 Genomic DNA. Translation: EDO49340.1.
RefSeq	XP_001641403.1. XM_001641353.1.
UniGene	Nve.7378.
3D structure databases
ProteinModelPortal	A7RHF7.
SMR	A7RHF7. Positions 1-224.
ModBase	Search...
Protein-protein interaction databases
STRING	45351.JGI177965.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	NEMVEDRAFT_v1g177965-RA; NEMVEDRAFT_v1g177965-PA; NEMVEDRAFT_v1g177965.
GeneID	5521502.
KEGG	nve:NEMVE_v1g177965.
Phylogenomic databases
eggNOG	COG1976.
HOGENOM	HOG000230605.
KO	K03264.
OMA	QFENSNE.
Family and domain databases
HAMAP	MF_00032. eIF_6.
InterPro	IPR002769. eIF6. [Graphical view]
PANTHER	PTHR10784. PTHR10784. 1 hit.
Pfam	PF01912. eIF-6. 1 hit. [Graphical view]
PIRSF	PIRSF006413. IF-6. 1 hit.
SMART	SM00654. eIF6. 1 hit. [Graphical view]
TIGRFAMs	TIGR00323. eIF-6. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A7RHF7_NEMVE

Accession

Primary (citable) accession number: A7RHF7

Entry history

Integrated into UniProtKB/TrEMBL:	October 2, 2007
Last sequence update:	October 2, 2007
Last modified:	April 3, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)