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A7PW81 (PGIP_VITVI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Polygalacturonase inhibitor
Alternative name(s):
Polygalacturonase-inhibiting protein
Short name=PGIG
Gene names
Name:pgip
ORF Names:GSVIVT00025506001, LOC100232865
OrganismVitis vinifera (Grape)
Taxonomic identifier29760 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis

Protein attributes

Sequence length333 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Inhibitor of fungal polygalacturonase. It is an important factor for plant resistance to phytopathogenic fungi.

Subcellular location

Secretedcell wall By similarity. Membrane; Peripheral membrane protein By similarity UniProtKB P58822.

Sequence similarities

Belongs to the polygalacturonase-inhibiting protein family.

Contains 7 LRR (leucine-rich) repeats.

Ontologies

Keywords
   Biological processPlant defense
   Cellular componentCell wall
Membrane
Secreted
   DomainLeucine-rich repeat
Repeat
Signal
   PTMDisulfide bond
Glycoprotein
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processdefense response

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentGolgi apparatus

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

extracellular region

Inferred from electronic annotation. Source: UniProtKB-KW

membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

plant-type cell wall

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

plasmodesma

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

   Molecular_functionpolygalacturonase inhibitor activity

Inferred from electronic annotation. Source: EnsemblPlants/Gramene

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2727 Potential
Chain28 – 333306Polygalacturonase inhibitor
PRO_0000363745

Regions

Repeat121 – 14424LRR 1
Repeat147 – 16923LRR 2
Repeat171 – 19222LRR 3
Repeat196 – 21722LRR 4
Repeat219 – 24123LRR 5
Repeat266 – 28823LRR 6
Repeat289 – 31123LRR 7

Amino acid modifications

Glycosylation1091N-linked (GlcNAc...) Potential
Glycosylation1331N-linked (GlcNAc...) Potential
Glycosylation1471N-linked (GlcNAc...) Potential
Glycosylation1571N-linked (GlcNAc...) Potential
Glycosylation2411N-linked (GlcNAc...) Potential
Glycosylation2941N-linked (GlcNAc...) Potential
Disulfide bond30 ↔ 60 By similarity UniProtKB P58822
Disulfide bond61 ↔ 68 By similarity UniProtKB P58822
Disulfide bond301 ↔ 323 By similarity UniProtKB P58822
Disulfide bond325 ↔ 332 By similarity UniProtKB P58822

Experimental info

Sequence conflict471N → T in AAK14075. Ref.1
Sequence conflict1351S → F in AAK14075. Ref.1
Sequence conflict1771L → I in AAK14075. Ref.1
Sequence conflict199 – 2013GLH → YLY in AAM74142. Ref.2
Sequence conflict2211N → T in AAM74142. Ref.2
Sequence conflict2341L → P in AAM74142. Ref.2

Sequences

Sequence LengthMass (Da)Tools
A7PW81 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: 0D4C502A6B93EF2D

FASTA33336,929
        10         20         30         40         50         60 
METSKLFLLS SSLLLVLLAT RPCPSLSERC NPKDKKVLLQ IKKALDNPYI LASWNPNTDC 

        70         80         90        100        110        120 
CGWYCVECDL TTHRINSLTI FSGQLSGQIP DAVGDLPFLE TLIFRKLSNL TGQIPPAIAK 

       130        140        150        160        170        180 
LKHLKMVRLS WTNLSGPVPA FFSELKNLTY LDLSFNNLSG PIPGSLSLLP NLGALHLDRN 

       190        200        210        220        230        240 
HLTGPIPDSF GKFAGSTPGL HLSHNQLSGK IPYSFRGFDP NVMDLSRNKL EGDLSIFFNA 

       250        260        270        280        290        300 
NKSTQIVDFS RNLFQFDLSR VEFPKSLTSL DLSHNKIAGS LPEMMTSLDL QFLNVSYNRL 

       310        320        330 
CGKIPVGGKL QSFDYDSYFH NRCLCGAPLQ SCK 

« Hide

References

« Hide 'large scale' references
[1]"Molecular cloning of a grapevine gene coding for polygalacturonase inhibiting protein."
Bezier A., Lambert B., Baillieul F.
Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Chardonnay.
Tissue: Leaf.
[2]"The isolation and characterization of a gene encoding a polygalacturonase-inhibiting protein (PGIP) from Vitis vinifera L."
De Ascensao A.R., Pretorius I.S., Bellstedt D.U., Burger J.T., Vivier M.A.
Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. Pinotage.
[3]"The grapevine genome sequence suggests ancestral hexaploidization in major angiosperm phyla."
Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., Casagrande A., Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., Legeai F., Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., Poulain J. expand/collapse author list , Bruyere C., Billault A., Segurens B., Gouyvenoux M., Ugarte E., Cattonaro F., Anthouard V., Vico V., Del Fabbro C., Alaux M., Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., Moroldo M., Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., Durand E., Pesole G., Laucou V., Chatelet P., Merdinoglu D., Delledonne M., Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., Pe M.E., Valle G., Morgante M., Caboche M., Adam-Blondon A.-F., Weissenbach J., Quetier F., Wincker P.
Nature 449:463-467(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Pinot noir / PN40024.
[4]Almagro L., Belchi-Navarro S., Pedreno M.A.
Submitted (JUL-2008) to UniProtKB
Cited for: PROTEIN SEQUENCE OF 172-179.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF305093 mRNA. Translation: AAK14075.1.
AF499451 Genomic DNA. Translation: AAM74142.1.
RefSeqNP_001268106.1. NM_001281177.1.
UniGeneVvi.9.

3D structure databases

ProteinModelPortalA7PW81.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING29760.GSVIVG00025506001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100232865.
KEGGvvi:100232865.

Phylogenomic databases

eggNOGNOG288515.

Family and domain databases

InterProIPR001611. Leu-rich_rpt.
IPR013210. LRR-contain_N2.
[Graphical view]
PfamPF00560. LRR_1. 1 hit.
PF08263. LRRNT_2. 1 hit.
[Graphical view]
PROSITEPS51450. LRR. 4 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGIP_VITVI
AccessionPrimary (citable) accession number: A7PW81
Secondary accession number(s): Q8LKV2, Q9AXP4
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: October 2, 2007
Last modified: April 16, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families