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Protein

Polygalacturonase inhibitor

Gene

pgip

Organism
Vitis vinifera (Grape)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Inhibitor of fungal polygalacturonase. It is an important factor for plant resistance to phytopathogenic fungi.Curated

GO - Biological processi

Keywordsi

Biological processPlant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Polygalacturonase inhibitorBy similarity
Alternative name(s):
Polygalacturonase-inhibiting proteinBy similarityImported
Short name:
PGIG
Gene namesi
Name:pgip
ORF Names:GSVIVT00025506001, LOC100232865
OrganismiVitis vinifera (Grape)
Taxonomic identifieri29760 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsVitalesVitaceaeVitis

Subcellular locationi

  • Secretedcell wall By similarity
  • Membrane By similarity; Peripheral membrane protein By similarity

GO - Cellular componenti

Keywords - Cellular componenti

Cell wall, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_000036374528 – 333Polygalacturonase inhibitorSequence analysisAdd BLAST306

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi30 ↔ 60By similarity
Disulfide bondi61 ↔ 68By similarity
Glycosylationi109N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi133N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi147N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi157N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi241N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Glycosylationi294N-linked (GlcNAc...) asparaginePROSITE-ProRule annotation1
Disulfide bondi301 ↔ 323By similarity
Disulfide bondi325 ↔ 332By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiA7PW81.

Structurei

3D structure databases

ProteinModelPortaliA7PW81.
SMRiA7PW81.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati72 – 96LRR 1Sequence analysisAdd BLAST25
Repeati97 – 120LRR 2Sequence analysisAdd BLAST24
Repeati121 – 144LRR 3Sequence analysisAdd BLAST24
Repeati145 – 169LRR 4Sequence analysisAdd BLAST25
Repeati170 – 192LRR 5Sequence analysisAdd BLAST23
Repeati194 – 220LRR 6Sequence analysisAdd BLAST27
Repeati221 – 240LRR 7Sequence analysisAdd BLAST20
Repeati241 – 263LRR 8Sequence analysisAdd BLAST23
Repeati264 – 288LRR 9Sequence analysisAdd BLAST25
Repeati290 – 312LRR 10Sequence analysisAdd BLAST23

Sequence similaritiesi

Belongs to the polygalacturonase-inhibiting protein family.Sequence analysis

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal

Phylogenomic databases

eggNOGiENOG410IG3D. Eukaryota.
ENOG410YB0Y. LUCA.

Family and domain databases

Gene3Di3.80.10.10. 1 hit.
InterProiView protein in InterPro
IPR032675. L_dom-like.
IPR001611. Leu-rich_rpt.
IPR013210. LRR_N_plant-typ.
PfamiView protein in Pfam
PF13516. LRR_6. 1 hit.
PF13855. LRR_8. 1 hit.
PF08263. LRRNT_2. 1 hit.
SUPFAMiSSF52058. SSF52058. 1 hit.
PROSITEiView protein in PROSITE
PS51450. LRR. 4 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A7PW81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METSKLFLLS SSLLLVLLAT RPCPSLSERC NPKDKKVLLQ IKKALDNPYI
60 70 80 90 100
LASWNPNTDC CGWYCVECDL TTHRINSLTI FSGQLSGQIP DAVGDLPFLE
110 120 130 140 150
TLIFRKLSNL TGQIPPAIAK LKHLKMVRLS WTNLSGPVPA FFSELKNLTY
160 170 180 190 200
LDLSFNNLSG PIPGSLSLLP NLGALHLDRN HLTGPIPDSF GKFAGSTPGL
210 220 230 240 250
HLSHNQLSGK IPYSFRGFDP NVMDLSRNKL EGDLSIFFNA NKSTQIVDFS
260 270 280 290 300
RNLFQFDLSR VEFPKSLTSL DLSHNKIAGS LPEMMTSLDL QFLNVSYNRL
310 320 330
CGKIPVGGKL QSFDYDSYFH NRCLCGAPLQ SCK
Length:333
Mass (Da):36,929
Last modified:October 2, 2007 - v1
Checksum:i0D4C502A6B93EF2D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti47N → T in AAK14075 (Ref. 1) Curated1
Sequence conflicti135S → F in AAK14075 (Ref. 1) Curated1
Sequence conflicti177L → I in AAK14075 (Ref. 1) Curated1
Sequence conflicti199 – 201GLH → YLY in AAM74142 (Ref. 2) Curated3
Sequence conflicti221N → T in AAM74142 (Ref. 2) Curated1
Sequence conflicti234L → P in AAM74142 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF305093 mRNA. Translation: AAK14075.1.
AF499451 Genomic DNA. Translation: AAM74142.1.
RefSeqiNP_001268106.1. NM_001281177.1.
UniGeneiVvi.9.

Genome annotation databases

GeneIDi100232865.
KEGGivvi:100232865.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiPGIP_VITVI
AccessioniPrimary (citable) accession number: A7PW81
Secondary accession number(s): Q8LKV2, Q9AXP4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: October 2, 2007
Last modified: July 5, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families