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Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Roseiflexus castenholzii (strain DSM 13941 / HLO8)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei52NucleophileUniRule annotation1
Binding sitei110SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciRCAS383372:G1G9S-4237-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotation
Ordered Locus Names:Rcas_3997
OrganismiRoseiflexus castenholzii (strain DSM 13941 / HLO8)
Taxonomic identifieri383372 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesRoseiflexineaeRoseiflexaceaeRoseiflexus
Proteomesi
  • UP000000263 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000770981 – 270tRNA pseudouridine synthase AAdd BLAST270

Proteomic databases

PRIDEiA7NR34

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi383372.Rcas_3997

Structurei

3D structure databases

ProteinModelPortaliA7NR34
SMRiA7NR34
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DI7 Bacteria
COG0101 LUCA
HOGENOMiHOG000248674
KOiK06173
OMAiFLYGMVR
OrthoDBiPOG091H010Q

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 2 hits
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00071 hisT_truA, 1 hit

Sequencei

Sequence statusi: Complete.

A7NR34-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNIALRIEY DGTDFVGSQW QTNGRSVQGA LEAAWQQLTG ERRRMILAGR
60 70 80 90 100
TDAGVHARGQ VANVSTNTRH SLATIIRGLN GVLPEDIGIL AAWEVPEEFH
110 120 130 140 150
ARYSAVRREY RYVIDNGRTP SPLLRRHAAY VPRRLDVAAM DRAIQQVIGT
160 170 180 190 200
HDFAPLSDGP QEGSTVRICY DARCTCTEVW GQPLVLIDVA ANAFLRHMVR
210 220 230 240 250
NLVGTLIQVG EGRIDADGFA AVLAGANRRA RVLAPAHGLY LMAVRYPEDG
260 270
NAAADTLVAA VGVTETRMQL
Length:270
Mass (Da):29,580
Last modified:October 2, 2007 - v1
Checksum:iF25D66CD4780F202
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000804 Genomic DNA Translation: ABU60030.1
RefSeqiWP_012122453.1, NC_009767.1

Genome annotation databases

EnsemblBacteriaiABU60030; ABU60030; Rcas_3997
KEGGirca:Rcas_3997

Similar proteinsi

Entry informationi

Entry nameiTRUA_ROSCS
AccessioniPrimary (citable) accession number: A7NR34
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: October 2, 2007
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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