A7NMK6 (A7NMK6_ROSCS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Deoxyribose-phosphate aldolase 1 HAMAP MF_00114
Short name=DERA 1 HAMAP MF_00114
EC=4.1.2.4 HAMAP MF_00114

Alternative name(s):
2-deoxy-D-ribose 5-phosphate aldolase 1 HAMAP MF_00114
Phosphodeoxyriboaldolase 1 HAMAP MF_00114

Gene names

Name:	deoC1 HAMAP MF_00114
Ordered Locus Names:	Rcas_2706

Organism

Roseiflexus castenholzii (strain DSM 13941 / HLO8) [Complete proteome] [HAMAP] EMBL ABU58777.1

Taxonomic identifier

383372 [NCBI]

Taxonomic lineage

Bacteria › Chloroflexi › Chloroflexales › Chloroflexaceae › Roseiflexus

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate By similarity. HAMAP MF_00114 SAAS SAAS022979
Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114 SAAS SAAS022979
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114 SAAS SAAS022979
Subcellular location	Cytoplasm By similarity HAMAP MF_00114 SAAS SAAS022979.
Sequence similarities	Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. HAMAP MF_00114

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00114 SAAS SAAS022979
Ligand	Schiff base SAAS SAAS022979 HAMAP MF_00114
Molecular function	Lyase HAMAP MF_00114 SAAS SAAS022979 EMBL ABU58777.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	153	1	Schiff-base intermediate with acetaldehyde By similarity HAMAP MF_00114
	Active site	182	1	By similarity HAMAP MF_00114

Sequences

	Sequence		Length	Mass (Da)
	A7NMK6 [UniParc]. Last modified October 2, 2007. Version 1. Checksum: BF1061FFAD60252E	FASTA	220	22,735
	10 20 30 40 50 60 MDIARMIDHT LLKPDATPQQ IAQLCAEARE YGFAAVCVNP VYVAQAAALL AGSVTVVCSV 70 80 90 100 110 120 AGFPLGANGT AAKVFETRQA IADGAREIDM VISIGHLKSG DDDHVRNDIR SVVETAHAGG 130 140 150 160 170 180 AICKVIIETA LLTDDEKRRA CTLSVEAGAD FVKTSTGFAS GGATVADVTL MRAVVGDRAR 190 200 210 220 IKAAGGIRTL ADAHAMIAAG ADRIGTSSGI AIVREKMSEK

References

[1]

"Complete sequence of Roseiflexus castenholzii DSM 13941." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Bryant D.A., Hanada S., Tsukatani Y., Richardson P. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13941 / HLO8.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000804 Genomic DNA. Translation: ABU58777.1.
RefSeq	YP_001432795.1. NC_009767.1.
3D structure databases
ProteinModelPortal	A7NMK6.
SMR	A7NMK6. Positions 2-216.
ModBase	Search...
Protein-protein interaction databases
STRING	A7NMK6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5540191.
GenomeReviews	Gene locus Rcas_2706 in contig CP000804_GR.
KEGG	rca:Rcas_2706.
PATRIC	23343946. VBIRosCas91182_3034.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0274.
HOGENOM	HBG636421.
OMA	IDHTNLK.
ProtClustDB	PRK00507.
Enzyme and pathway databases
BioCyc	RCAS383372:RCAS_2706-MONOMER.
Family and domain databases
HAMAP	MF_00114. DeoC_type1. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. IPR022979. Deoxyribose_phosphate_aldo_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01619.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. DeoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A7NMK6_ROSCS

Accession

Primary (citable) accession number: A7NMK6

Entry history

Integrated into UniProtKB/TrEMBL:	October 2, 2007
Last sequence update:	October 2, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)