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A7NMC9

- A7NMC9_ROSCS

UniProt

A7NMC9 - A7NMC9_ROSCS

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Protein
Xylose isomerase
Gene
xylA, Rcas_2618
Organism
Roseiflexus castenholzii (strain DSM 13941 / HLO8)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei56 – 561 By similarityUniRule annotation
Active sitei59 – 591 By similarityUniRule annotation
Metal bindingi183 – 1831Magnesium 1 By similarityUniRule annotation
Metal bindingi219 – 2191Magnesium 1 By similarityUniRule annotation
Metal bindingi219 – 2191Magnesium 2 By similarityUniRule annotation
Metal bindingi222 – 2221Magnesium 2 By similarityUniRule annotation
Metal bindingi247 – 2471Magnesium 1 By similarityUniRule annotation
Metal bindingi289 – 2891Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciRCAS383372:GH89-2644-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Rcas_2618Imported
OrganismiRoseiflexus castenholzii (strain DSM 13941 / HLO8)Imported
Taxonomic identifieri383372 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesRoseiflexineaeRoseiflexaceaeRoseiflexus
ProteomesiUP000000263: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi383372.Rcas_2618.

Structurei

3D structure databases

ProteinModelPortaliA7NMC9.
SMRiA7NMC9. Positions 4-389.

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2115.
HOGENOMiHOG000022596.
KOiK01805.
OMAiDLIPIDA.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02631. xylA_Arthro. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7NMC9-1 [UniParc]FASTAAdd to Basket

« Hide

MSDMYEPKPE HKFTFGLWTV GNIGRDPFGE PVRHPLSPVE IVHLLADVGA    50
YGVNFHDNDL IPIDATPADR DRILREFKAA LQETGLVVPM ATTNLFADPV 100
FKDGAFTSND PKVRAYALQK TMRAIDLGVE CGAKVYVFWG GREGVESDAA 150
KDPQEGLKRY REVINFLCAY VKDQGYDLKF ALEPKPNEPR GDIYLATVGH 200
ALAFINTLDH PDMVGLNPEV AHETMAGLNF LHGVAQAWDA GKLFHIDLND 250
QVIGRYDQDF RFGAVNLKAA FFLVRFLENV GYQGSRHFDA HAYRTEDYEG 300
VKTFARGCMR TYLILKEKAR RFDGDAEIQA LLAEITADDG TMAPFQGGYS 350
RDKADALKAH PFDRVALGRR GLAYERLDQL TNELLLGVR 389
Length:389
Mass (Da):43,519
Last modified:October 2, 2007 - v1
Checksum:i2FB80952CBABBDCB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000804 Genomic DNA. Translation: ABU58691.1.
RefSeqiYP_001432709.1. NC_009767.1.

Genome annotation databases

EnsemblBacteriaiABU58691; ABU58691; Rcas_2618.
GeneIDi5540100.
KEGGirca:Rcas_2618.
PATRICi23343745. VBIRosCas91182_2937.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000804 Genomic DNA. Translation: ABU58691.1 .
RefSeqi YP_001432709.1. NC_009767.1.

3D structure databases

ProteinModelPortali A7NMC9.
SMRi A7NMC9. Positions 4-389.
ModBasei Search...

Protein-protein interaction databases

STRINGi 383372.Rcas_2618.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABU58691 ; ABU58691 ; Rcas_2618 .
GeneIDi 5540100.
KEGGi rca:Rcas_2618.
PATRICi 23343745. VBIRosCas91182_2937.

Phylogenomic databases

eggNOGi COG2115.
HOGENOMi HOG000022596.
KOi K01805.
OMAi DLIPIDA.
OrthoDBi EOG62NX4R.

Enzyme and pathway databases

BioCyci RCAS383372:GH89-2644-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02631. xylA_Arthro. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13941 / HLO8.

Entry informationi

Entry nameiA7NMC9_ROSCS
AccessioniPrimary (citable) accession number: A7NMC9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: September 3, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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