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A7NMC9

- A7NMC9_ROSCS

UniProt

A7NMC9 - A7NMC9_ROSCS

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Protein

Xylose isomerase

Gene

xylA

Organism
Roseiflexus castenholzii (strain DSM 13941 / HLO8)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Note: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei56 – 561UniRule annotation
Active sitei59 – 591UniRule annotation
Metal bindingi183 – 1831Magnesium 1UniRule annotation
Metal bindingi219 – 2191Magnesium 1UniRule annotation
Metal bindingi219 – 2191Magnesium 2UniRule annotation
Metal bindingi222 – 2221Magnesium 2UniRule annotation
Metal bindingi247 – 2471Magnesium 1UniRule annotation
Metal bindingi289 – 2891Magnesium 1UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotation, Xylose metabolismUniRule annotation

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciRCAS383372:GH89-2644-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Rcas_2618Imported
OrganismiRoseiflexus castenholzii (strain DSM 13941 / HLO8)Imported
Taxonomic identifieri383372 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesRoseiflexineaeRoseiflexaceaeRoseiflexus
ProteomesiUP000000263: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi383372.Rcas_2618.

Structurei

3D structure databases

ProteinModelPortaliA7NMC9.
SMRiA7NMC9. Positions 4-389.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2115.
HOGENOMiHOG000022596.
KOiK01805.
OMAiDLIPIDA.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02631. xylA_Arthro. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7NMC9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSDMYEPKPE HKFTFGLWTV GNIGRDPFGE PVRHPLSPVE IVHLLADVGA
60 70 80 90 100
YGVNFHDNDL IPIDATPADR DRILREFKAA LQETGLVVPM ATTNLFADPV
110 120 130 140 150
FKDGAFTSND PKVRAYALQK TMRAIDLGVE CGAKVYVFWG GREGVESDAA
160 170 180 190 200
KDPQEGLKRY REVINFLCAY VKDQGYDLKF ALEPKPNEPR GDIYLATVGH
210 220 230 240 250
ALAFINTLDH PDMVGLNPEV AHETMAGLNF LHGVAQAWDA GKLFHIDLND
260 270 280 290 300
QVIGRYDQDF RFGAVNLKAA FFLVRFLENV GYQGSRHFDA HAYRTEDYEG
310 320 330 340 350
VKTFARGCMR TYLILKEKAR RFDGDAEIQA LLAEITADDG TMAPFQGGYS
360 370 380
RDKADALKAH PFDRVALGRR GLAYERLDQL TNELLLGVR
Length:389
Mass (Da):43,519
Last modified:October 2, 2007 - v1
Checksum:i2FB80952CBABBDCB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000804 Genomic DNA. Translation: ABU58691.1.
RefSeqiYP_001432709.1. NC_009767.1.

Genome annotation databases

EnsemblBacteriaiABU58691; ABU58691; Rcas_2618.
GeneIDi5540100.
KEGGirca:Rcas_2618.
PATRICi23343745. VBIRosCas91182_2937.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000804 Genomic DNA. Translation: ABU58691.1 .
RefSeqi YP_001432709.1. NC_009767.1.

3D structure databases

ProteinModelPortali A7NMC9.
SMRi A7NMC9. Positions 4-389.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 383372.Rcas_2618.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABU58691 ; ABU58691 ; Rcas_2618 .
GeneIDi 5540100.
KEGGi rca:Rcas_2618.
PATRICi 23343745. VBIRosCas91182_2937.

Phylogenomic databases

eggNOGi COG2115.
HOGENOMi HOG000022596.
KOi K01805.
OMAi DLIPIDA.
OrthoDBi EOG62NX4R.

Enzyme and pathway databases

BioCyci RCAS383372:GH89-2644-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02631. xylA_Arthro. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13941 / HLO8Imported.

Entry informationi

Entry nameiA7NMC9_ROSCS
AccessioniPrimary (citable) accession number: A7NMC9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: November 26, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3