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A7NJG4 (A7NJG4_ROSCS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Aerobic magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase HAMAP MF_01840

Short name=Aerobic Mg-protoporphyrin IX monomethyl ester oxidative cyclase HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF HAMAP MF_01840
Ordered Locus Names:Rcas_1541
OrganismRoseiflexus castenholzii (strain DSM 13941 / HLO8) [Complete proteome] [HAMAP] EMBL ABU57634.1
Taxonomic identifier383372 [NCBI]
Taxonomic lineageBacteriaChloroflexiChloroflexalesChloroflexaceaeRoseiflexus

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; bacteriochlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
A7NJG4 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: 7B91A7CD14686330

FASTA37143,903
        10         20         30         40         50         60 
MINMPGEYSP TTRHALREAI LNPRFYTTDF RAIDRLNVAH MRDEFDWIRN EFEFDYNKKH 

        70         80         90        100        110        120 
FVRNEEFLAN FDDMPARDLF IEFLERSCTA EFSGCLLYAE MVKHLHDPTL RAIFRCMSRD 

       130        140        150        160        170        180 
EGRHAGFLNK TMADLGVEMN LQVLHTRKKY TYFQPKFIFY SVYLSEKIGY ARYITIYRHL 

       190        200        210        220        230        240 
QHHPQGMIHP IFKWFEKWCN DEYRHGEFFS LLMRSQPDLL RGGNLRWIRF FLLAVYATMY 

       250        260        270        280        290        300 
LNDARRAGFY EALGLNWRDY DQRVIRLTNH IATQVFPVTL PVDDPRFFRH LDACVRYDAQ 

       310        320        330        340        350        360 
IRALEGRNDP IAQVQRARLG AGIAARLLAT YRLPPAPTTD ANRWKGLEGF PNYPGPGWKQ 

       370 
DASLNERVIS A 

« Hide

References

[1]"Complete sequence of Roseiflexus castenholzii DSM 13941."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Bryant D.A., Hanada S., Tsukatani Y., Richardson P.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13941 / HLO8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000804 Genomic DNA. Translation: ABU57634.1.
RefSeqYP_001431652.1. NC_009767.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA7NJG4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5539017.
GenomeReviewsGene locus Rcas_1541 in contig CP000804_GR.
KEGGrca:Rcas_1541.
PATRIC23341353. VBIRosCas91182_1747.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG10633.
HOGENOMHBG284843.
OMAHGDFFDA.
ProtClustDBPRK13654.

Enzyme and pathway databases

BioCycRCAS383372:RCAS_1541-MONOMER.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR012347. Ferritin-rel.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
Gene3DG3DSA:1.20.1260.10. Ferritin_rel. 1 hit.
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA7NJG4_ROSCS
AccessionPrimary (citable) accession number: A7NJG4
Entry history
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)