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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Roseiflexus castenholzii (strain DSM 13941 / HLO8)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathway:igluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathway:iglycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi)
  3. 6-phosphofructokinase (Rcas_1875), 6-phosphofructokinase (Rcas_2515), 6-phosphofructokinase (Rcas_2513)
  4. no protein annotated in this organism
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei384 – 3841UniRule annotation
Active sitei504 – 5041UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciRCAS383372:GH89-719-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:Rcas_0710
OrganismiRoseiflexus castenholzii (strain DSM 13941 / HLO8)
Taxonomic identifieri383372 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesRoseiflexineaeRoseiflexaceaeRoseiflexus
ProteomesiUP000000263 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 543543Glucose-6-phosphate isomerasePRO_1000206371Add
BLAST

Proteomic databases

PRIDEiA7NH85.

Interactioni

Protein-protein interaction databases

STRINGi383372.Rcas_0710.

Structurei

3D structure databases

ProteinModelPortaliA7NH85.
SMRiA7NH85. Positions 1-539.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiSHLIAPY.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A7NH85-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLLTQIPEW RALETHYRAI RDVHLRRLFA EDPGRGERMT AEAAGLFFDY
60 70 80 90 100
SKNRVTDETL RLLMALAEAR GLRARIDAMF RGERINITEN RAVLHVALRA
110 120 130 140 150
PRGAVILVDG VNVVPDVHAV LDRMAAFAEQ VRSGAWSGFT GKPIRNIVNI
160 170 180 190 200
GIGGSDLGPV MAYEALRSYS RRNLTLRFVS NIDGNDFAEA TRDLDPAETL
210 220 230 240 250
FIVASKTFTT LETMTNARTA RAWLLAALGD DAAVARHFVA VSTNAAEVAK
260 270 280 290 300
FGIDTANMFG FWDWVGGRYS MTSAIGLSTM IALGPDHFRD MLAGFHAMDE
310 320 330 340 350
HFRTAPFDRN LPVIHGLLTV WYANFFGVET VAILPYDNYL KRFPAYLQQL
360 370 380 390 400
TMESNGKSVT LSGEPVTYQT GPIYWGEPGT NGQHSFYQLI HQGTRLVLCD
410 420 430 440 450
FIGFAETLNP LGAHHDLLMA NMFAQAEALA FGKTTEEALA EGTPAWLAPH
460 470 480 490 500
RTFPGNRPSN TFLAERLTPA VLGALVALYE HSVFTQGAIW DINSFDQWGV
510 520 530 540
ELGKVLAGRI APELMSEVAP SPAHDSSTNA LIRRYRAWRG RAL
Length:543
Mass (Da):60,047
Last modified:October 2, 2007 - v1
Checksum:iA03ABDA05C9AD87C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000804 Genomic DNA. Translation: ABU56832.1.
RefSeqiWP_012119262.1. NC_009767.1.

Genome annotation databases

EnsemblBacteriaiABU56832; ABU56832; Rcas_0710.
KEGGirca:Rcas_0710.
PATRICi23339487. VBIRosCas91182_0824.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000804 Genomic DNA. Translation: ABU56832.1.
RefSeqiWP_012119262.1. NC_009767.1.

3D structure databases

ProteinModelPortaliA7NH85.
SMRiA7NH85. Positions 1-539.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi383372.Rcas_0710.

Proteomic databases

PRIDEiA7NH85.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABU56832; ABU56832; Rcas_0710.
KEGGirca:Rcas_0710.
PATRICi23339487. VBIRosCas91182_0824.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiSHLIAPY.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciRCAS383372:GH89-719-MONOMER.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13941 / HLO8.

Entry informationi

Entry nameiG6PI_ROSCS
AccessioniPrimary (citable) accession number: A7NH85
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: October 2, 2007
Last modified: July 22, 2015
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.