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A7NFK4 (A7NFK4_ROSCS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase HAMAP MF_00110

EC=4.2.3.4 HAMAP MF_00110
Gene names
Name:aroB HAMAP MF_00110
Ordered Locus Names:Rcas_0093
OrganismRoseiflexus castenholzii (strain DSM 13941 / HLO8) [Complete proteome] [HAMAP] EMBL ABU56230.1
Taxonomic identifier383372 [NCBI]
Taxonomic lineageBacteriaChloroflexiChloroflexalesChloroflexaceaeRoseiflexus

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family. HAMAP MF_00110

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis HAMAP MF_00110
   Cellular componentCytoplasm HAMAP MF_00110
   LigandNAD HAMAP MF_00110
   Molecular functionLyase HAMAP MF_00110 EMBL ABU56230.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A7NFK4 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: 0881C277C830AC4D

FASTA37140,132
        10         20         30         40         50         60 
MTQPAEYLYV TTTGGRYEVI VAHGAFDHLP HHLQRIGLRG AAWVISDDQV FPRYAPALIA 

        70         80         90        100        110        120 
RLRAAGYNAH GYAVPPGEPS KDLAMAARLY DWLIGNGVER RDTVLALGGG VIGDLAGFVA 

       130        140        150        160        170        180 
ATVLRGIALV HLPTTLLAMV DSAIGGKTGV NHSLGKNLIG AFHQPRLTLA DTTTLATLPP 

       190        200        210        220        230        240 
RELRAGWAEV IKHAVIRDAD LFAHLEAITD PASLQGDALA TIIRRAARVK IDIVNIDERE 

       250        260        270        280        290        300 
TGERMLLNYG HTLGHAIEAA RGYGDLLHGE AVAIGMHLEA QIAHRMGMVD SRFVERQQRL 

       310        320        330        340        350        360 
LRAYGLPTNL PPGVTIDDLI ERTLRDKKVR AGRARWALPL GIGAATVRDD VPETVVRAIL 

       370 
EKATDRNEGP V 

« Hide

References

[1]"Complete sequence of Roseiflexus castenholzii DSM 13941."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Thompson L.S., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Bryant D.A., Hanada S., Tsukatani Y., Richardson P.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13941 / HLO8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000804 Genomic DNA. Translation: ABU56230.1.
RefSeqYP_001430248.1. NC_009767.1.

3D structure databases

ProteinModelPortalA7NFK4.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7NFK4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5537552.
GenomeReviewsGene locus Rcas_0093 in contig CP000804_GR.
KEGGrca:Rcas_0093.
PATRIC23338066. VBIRosCas91182_0119.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAGTFTQPD.
ProtClustDBCLSK975397.

Enzyme and pathway databases

BioCycRCAS383372:RCAS_0093-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA7NFK4_ROSCS
AccessionPrimary (citable) accession number: A7NFK4
Entry history
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)