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A7NDI3

- G6PI_FRATF

UniProt

A7NDI3 - G6PI_FRATF

Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Francisella tularensis subsp. holarctica (strain FTNF002-00 / FTA)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (02 Oct 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei346 – 3461Proton donorUniRule annotation
    Active sitei377 – 3771UniRule annotation
    Active sitei505 – 5051UniRule annotation

    GO - Molecular functioni

    1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Gluconeogenesis, Glycolysis

    Enzyme and pathway databases

    BioCyciFTUL458234:GH31-1422-MONOMER.
    UniPathwayiUPA00109; UER00181.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
    Short name:
    GPIUniRule annotation
    Alternative name(s):
    Phosphoglucose isomeraseUniRule annotation
    Short name:
    PGIUniRule annotation
    Phosphohexose isomeraseUniRule annotation
    Short name:
    PHIUniRule annotation
    Gene namesi
    Name:pgiUniRule annotation
    Ordered Locus Names:FTA_1561
    OrganismiFrancisella tularensis subsp. holarctica (strain FTNF002-00 / FTA)
    Taxonomic identifieri458234 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
    ProteomesiUP000000261: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 540540Glucose-6-phosphate isomerasePRO_1000013966Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi119857.FTL_1476.

    Structurei

    3D structure databases

    ProteinModelPortaliA7NDI3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GPI family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0166.
    HOGENOMiHOG000261370.
    KOiK01810.
    OMAiNCHFVAN.
    OrthoDBiEOG64R61J.

    Family and domain databases

    Gene3Di1.10.1390.10. 1 hit.
    HAMAPiMF_00473. G6P_isomerase.
    InterProiIPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view]
    PANTHERiPTHR11469. PTHR11469. 1 hit.
    PfamiPF00342. PGI. 1 hit.
    [Graphical view]
    PRINTSiPR00662. G6PISOMERASE.
    PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7NDI3-1 [UniParc]FASTAAdd to Basket

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    MLFCDDSKKY LKEQNINLKN EFDKDDKRVE KFSLKHQNIY FDYSKNLINN    50
    YILKSLLESA EKSSLKDKIK QMFNGAKINS TEHRAVLHTA LRDLSSTPLI 100
    VDGQDIRQEV TKEKQRVKEL VEKVVSGRWR GFSGKKITDI VNIGIGGSDL 150
    GPKMVVRALQ PYHCTDLKVH FVSNVDADSL LQALHVVDPE TTLFIIASKS 200
    FSTEETLLNS ISAREWLLDH YEDEKAVANH FVAISSKLDK VKEFGIDLEH 250
    CYKMWDWVGG RYSLWSSIGM SIAFAIGYDN FEKLLAGAYS VDKYFKETEF 300
    SKNIPVIMAL LASYYSCTYN SQSQALLPYD ERLCYFVDYL QQADMESNGK 350
    SVNIAGGTVN YQTGVVLWGG VGTNGQHAFH QLLHQGNIFI PVDFIAIATS 400
    HHNYDNHQQA LLANCFAQSQ ALMFGQSYDM VYNELLKSGL NETQAKKLAA 450
    HKVIPGNRPS TTILLDELSP YSLGALIALY EHKIFVQGVL WDINSYDQWG 500
    VELGKKLGKN ILKAMNDDSS DEYQNLDDST RQLIAKVKNK 540
    Length:540
    Mass (Da):61,104
    Last modified:October 2, 2007 - v1
    Checksum:i4009BDBC10C7C21B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000803 Genomic DNA. Translation: ABU62036.1.
    RefSeqiYP_001428992.1. NC_009749.1.

    Genome annotation databases

    EnsemblBacteriaiABU62036; ABU62036; FTA_1561.
    GeneIDi5523915.
    KEGGifta:FTA_1561.
    PATRICi17948550. VBIFraTul129798_1627.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000803 Genomic DNA. Translation: ABU62036.1 .
    RefSeqi YP_001428992.1. NC_009749.1.

    3D structure databases

    ProteinModelPortali A7NDI3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 119857.FTL_1476.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABU62036 ; ABU62036 ; FTA_1561 .
    GeneIDi 5523915.
    KEGGi fta:FTA_1561.
    PATRICi 17948550. VBIFraTul129798_1627.

    Phylogenomic databases

    eggNOGi COG0166.
    HOGENOMi HOG000261370.
    KOi K01810.
    OMAi NCHFVAN.
    OrthoDBi EOG64R61J.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00181 .
    UPA00138 .
    BioCyci FTUL458234:GH31-1422-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1390.10. 1 hit.
    HAMAPi MF_00473. G6P_isomerase.
    InterProi IPR001672. G6P_Isomerase.
    IPR023096. G6P_Isomerase_C.
    IPR018189. Phosphoglucose_isomerase_CS.
    [Graphical view ]
    PANTHERi PTHR11469. PTHR11469. 1 hit.
    Pfami PF00342. PGI. 1 hit.
    [Graphical view ]
    PRINTSi PR00662. G6PISOMERASE.
    PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
    PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
    PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: FTNF002-00 / FTA.

    Entry informationi

    Entry nameiG6PI_FRATF
    AccessioniPrimary (citable) accession number: A7NDI3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: October 2, 2007
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3