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A7NA00

- A7NA00_FRATF

UniProt

A7NA00 - A7NA00_FRATF

Protein

Dephospho-CoA kinase

Gene

coaE

Organism
Francisella tularensis subsp. holarctica (strain FTNF002-00 / FTA)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (02 Oct 2007)
      Previous versions | rss
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    Functioni

    Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.UniRule annotation

    Catalytic activityi

    ATP + 3'-dephospho-CoA = ADP + CoA.UniRule annotation

    Pathwayi

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi13 – 208ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. dephospho-CoA kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. coenzyme A biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    KinaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    Coenzyme A biosynthesisUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciFTUL458234:GH31-306-MONOMER.
    UniPathwayiUPA00241; UER00356.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Dephospho-CoA kinaseUniRule annotation (EC:2.7.1.24UniRule annotation)
    Alternative name(s):
    Dephosphocoenzyme A kinaseUniRule annotation
    Gene namesi
    Name:coaEUniRule annotationImported
    Ordered Locus Names:FTA_0326Imported
    OrganismiFrancisella tularensis subsp. holarctica (strain FTNF002-00 / FTA)Imported
    Taxonomic identifieri458234 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
    ProteomesiUP000000261: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi458234.FTA_0326.

    Structurei

    3D structure databases

    ProteinModelPortaliA7NA00.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the CoaE family.UniRule annotation
    Contains 1 DPCK (dephospho-CoA kinase) domain.UniRule annotation
    Contains DPCK (dephospho-CoA kinase) domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG0237.
    HOGENOMiHOG000020768.
    KOiK00859.
    OMAiRERVFNH.
    OrthoDBiEOG6HTP3H.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00376. Dephospho_CoA_kinase.
    InterProiIPR001977. Depp_CoAkinase.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF01121. CoaE. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00152. TIGR00152. 1 hit.
    PROSITEiPS51219. DPCK. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A7NA00-1 [UniParc]FASTAAdd to Basket

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    MNFINTYPIG ITGGIASGKS TATRILKEKL NLNVVCADTI SREITKKPSV    50
    IKKIAEKFGD EIVMNKQINR AMLRAIITES KEAKKWLEDY LHPVINKEIK 100
    KQVKESDTVM TIVDIPLLGP YNFRHYDYLK KVIVIKADLE TRIRRLMERD 150
    GKNRQQAVAF INLQISDKER EKIADFVIDN TELTDQELES KLITTINEIT 200
    NLTN 204
    Length:204
    Mass (Da):23,434
    Last modified:October 2, 2007 - v1
    Checksum:i44556AEF2806D7C1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000803 Genomic DNA. Translation: ABU60803.1.
    RefSeqiYP_001427759.1. NC_009749.1.

    Genome annotation databases

    EnsemblBacteriaiABU60803; ABU60803; FTA_0326.
    GeneIDi5522977.
    KEGGifta:FTA_0326.
    PATRICi17945914. VBIFraTul129798_0343.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000803 Genomic DNA. Translation: ABU60803.1 .
    RefSeqi YP_001427759.1. NC_009749.1.

    3D structure databases

    ProteinModelPortali A7NA00.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 458234.FTA_0326.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABU60803 ; ABU60803 ; FTA_0326 .
    GeneIDi 5522977.
    KEGGi fta:FTA_0326.
    PATRICi 17945914. VBIFraTul129798_0343.

    Phylogenomic databases

    eggNOGi COG0237.
    HOGENOMi HOG000020768.
    KOi K00859.
    OMAi RERVFNH.
    OrthoDBi EOG6HTP3H.

    Enzyme and pathway databases

    UniPathwayi UPA00241 ; UER00356 .
    BioCyci FTUL458234:GH31-306-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00376. Dephospho_CoA_kinase.
    InterProi IPR001977. Depp_CoAkinase.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF01121. CoaE. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00152. TIGR00152. 1 hit.
    PROSITEi PS51219. DPCK. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: FTNF002-00 / FTAImported.

    Entry informationi

    Entry nameiA7NA00_FRATF
    AccessioniPrimary (citable) accession number: A7NA00
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 2, 2007
    Last sequence update: October 2, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3