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A7N9A7 (A7N9A7_FRATF) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide deformylase 1 HAMAP MF_00163
Short name=PDF 1 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 1 HAMAP MF_00163
Gene names
Name:def1 HAMAP MF_00163 EMBL ABU60560.1
Ordered Locus Names:FTA_0082
OrganismFrancisella tularensis subsp. holarctica (strain FTNF002-00 / FTA) [Complete proteome] [HAMAP]
Taxonomic identifier458234 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Thiotrichales › Francisellaceae › Francisella

Protein attributes

Sequence length174 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163 RuleBase RU003335

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1391 By similarity HAMAP MF_00163
Metal binding961Iron By similarity HAMAP MF_00163
Metal binding1381Iron By similarity HAMAP MF_00163
Metal binding1421Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
A7N9A7 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: 4A6B39EA500E8EAD

FASTA17419,824
        10         20         30         40         50         60 
MNMSLEILKY PHPVLKEVAK EVTKDEINDD LRATIAEMHE LMLEANGVGL AAIQVGIKKR 

        70         80         90        100        110        120 
FFIMYDNLEE QNPEIITIIN PEIIEQNGKI IDEEGCLSFP GVSAKVNRAT VVKIKALNEF 

       130        140        150        160        170 
GEEIEVEKDG FLARCIQHEI DHLNGITFFD HLGSLKRKMI EKKYKKLMQE NAKS

« Hide

References

[1]"Complete genome sequence of Francisella tularensis subspecies holarctica FTNF002-00."
Barabote R.D., Xie G., Brettin T.S., Hinrichs S.H., Fey P.D., Jay J.J., Engle J.L., Godbole S.D., Noronha J.M., Scheuermann R.H., Zhou L.W., Lion C., Dempsey M.P.
PLoS ONE 4:E7041-E7041(2009) [PubMed: 19756146] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000803 Genomic DNA. Translation: ABU60560.1.
RefSeqYP_001427516.1. NC_009749.1.

3D structure databases

ProteinModelPortalA7N9A7.
ModBaseSearch...

Protein-protein interaction databases

STRINGA7N9A7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5524583.
GenomeReviewsGene locus FTA_0082 in contig CP000803_GR.
KEGGfta:FTA_0082.
PATRIC17945379. VBIFraTul129798_0085.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0242.
HOGENOMHBG665227.
OMAEMTELMI.
ProtClustDBCLSK935135.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA7N9A7_FRATF
AccessionPrimary (citable) accession number: A7N9A7
Entry history
Integrated into UniProtKB/TrEMBL: October 2, 2007
Last sequence update: October 2, 2007
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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