Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A7N4I5 (PNCB_VIBCB) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:VIBHAR_06575
OrganismVibrio campbellii (strain ATCC BAA-1116 / BB120) [Complete proteome] [HAMAP]
Taxonomic identifier338187 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length436 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 436436Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000025017

Sequences

Sequence LengthMass (Da)Tools
A7N4I5 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: B86A87652B4D6C1C

FASTA43649,687
        10         20         30         40         50         60 
MTTNLFSSRI IQSALDFDVY KVNMMSAVAA LYPDAMVSYK FIVRSEEDLS ELLPEVKAEV 

        70         80         90        100        110        120 
LKLQDITFST EEIEYIKGVA PYLNPEFVDA LHAFRFNPQR DVSFNIKTMA DGTSQLRITI 

       130        140        150        160        170        180 
NGLWKETILY ETIIMSIVSE VRSRARWAEV PVEQFQSVLE EKVRHLKTEL KRRNITNFKF 

       190        200        210        220        230        240 
ADMSTRRRFS FQAQRSMLKY LSKELPDCLT GTSNYHLAKE LGLTPIGTVA HEWFMGHQAL 

       250        260        270        280        290        300 
VNVRDSQKVA LQRWQKMFNG ALGIALTDTI GIDAFLKDFD EELSNAYVGV RHDSGCPYTW 

       310        320        330        340        350        360 
GEKMIEHYQS LGIDPMTKTL VFTDGLNFEQ ALAICEHFQD RVQVSFGIGT SLANDMGDYA 

       370        380        390        400        410        420 
NAQGIAYKPL SIVIKMVSCN GSPVAKISDE PEKAMCEDIF FLMNLKRRFE QPLDLDECRG 

       430 
LIDRLEDEGD NYLIDA 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000790 Genomic DNA. Translation: ABU74466.1.
RefSeqYP_001448693.1. NC_009784.1.
YP_008528458.1. NC_022270.1.

3D structure databases

ProteinModelPortalA7N4I5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING338187.VIBHAR_06575.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABU74466; ABU74466; VIBHAR_06575.
GeneID16818019.
5558570.
KEGGvha:VIBHAR_06575.
PATRIC20137290. VBIVibHar24526_5123.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycVHAR338187:GJCH-5560-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_VIBCB
AccessionPrimary (citable) accession number: A7N4I5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: March 19, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways