Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Methylglyoxal synthase

Gene

mgsA

Organism
Vibrio campbellii (strain ATCC BAA-1116 / BB120)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.UniRule annotation

Catalytic activityi

Glycerone phosphate = methylglyoxal + phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei19SubstrateUniRule annotation1
Binding sitei23SubstrateUniRule annotation1
Active sitei71Proton donor/acceptorUniRule annotation1
Binding sitei98SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase

Names & Taxonomyi

Protein namesi
Recommended name:
Methylglyoxal synthaseUniRule annotation (EC:4.2.3.3UniRule annotation)
Short name:
MGSUniRule annotation
Gene namesi
Name:mgsAUniRule annotation
Ordered Locus Names:VIBHAR_06121
OrganismiVibrio campbellii (strain ATCC BAA-1116 / BB120)
Taxonomic identifieri338187 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000008152 Componenti: Chromosome II

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000178321 – 151Methylglyoxal synthaseAdd BLAST151

Interactioni

Protein-protein interaction databases

STRINGi338187.VIBHAR_06121

Structurei

3D structure databases

ProteinModelPortaliA7N2T8
SMRiA7N2T8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 151MGS-likeUniRule annotationAdd BLAST146

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni45 – 48Substrate bindingUniRule annotation4
Regioni65 – 66Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the methylglyoxal synthase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108Z5K Bacteria
COG1803 LUCA
HOGENOMiHOG000283729
KOiK01734
OMAiRACDVHN

Family and domain databases

CDDicd01422 MGS, 1 hit
Gene3Di3.40.50.1380, 1 hit
HAMAPiMF_00549 Methylglyoxal_synth, 1 hit
InterProiView protein in InterPro
IPR004363 Methylgl_synth
IPR018148 Methylglyoxal_synth_AS
IPR011607 MGS-like_dom
IPR036914 MGS-like_dom_sf
PANTHERiPTHR30492 PTHR30492, 1 hit
PfamiView protein in Pfam
PF02142 MGS, 1 hit
PIRSFiPIRSF006614 Methylglyox_syn, 1 hit
SMARTiView protein in SMART
SM00851 MGS, 1 hit
SUPFAMiSSF52335 SSF52335, 1 hit
TIGRFAMsiTIGR00160 MGSA, 1 hit
PROSITEiView protein in PROSITE
PS01335 METHYLGLYOXAL_SYNTH, 1 hit
PS51855 MGS, 1 hit

Sequencei

Sequence statusi: Complete.

A7N2T8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKTTRTMPA HKHVALVAHD NCKPELLRWV KENKEKLQSH FLYATGTTGH
60 70 80 90 100
MLSKETGLAI KSMISGPMGG DQQLGALISE GNIDVLVFFW DPLNAVPHDP
110 120 130 140 150
DVKALLRIAS VWNIPVATNR ATAKFLFNSP LIDQEVDIEV PDYDAYLAER

T
Length:151
Mass (Da):16,822
Last modified:October 2, 2007 - v1
Checksum:i44ACBBF11D0C87A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000790 Genomic DNA Translation: ABU74014.1
RefSeqiWP_005431754.1, NC_022270.1

Genome annotation databases

EnsemblBacteriaiABU74014; ABU74014; VIBHAR_06121
GeneIDi5558064
KEGGivca:M892_21350
vha:VIBHAR_06121
PATRICifig|338187.25.peg.4202

Similar proteinsi

Entry informationi

Entry nameiMGSA_VIBCB
AccessioniPrimary (citable) accession number: A7N2T8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: March 28, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health