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Reviewed, UniProtKB/Swiss-Prot A7N2Q0 (BETB_VIBHB)

Last modified June 16, 2009. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Betaine aldehyde dehydrogenase
      Short name=BADH
    EC=1.2.1.8
Gene names
Name: betB
Ordered Locus Names: VIBHAR_06180
OrganismVibrio harveyi (strain ATCC BAA-1116 / BB120) [Complete proteome] [HAMAP]
Taxonomic identifier338187 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

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Protein attributes

Sequence length486 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP MF_00804

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP MF_00804

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

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Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglycine betaine biosynthetic process from choline

Inferred from electronic annotation. Source: HAMAP

oxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 486486Betaine aldehyde dehydrogenase HAMAP MF_00804
PRO_1000047059

Regions

Nucleotide binding225 – 2306NAD By similarity

Sites

Active site2471 By similarity
Active site2811 By similarity

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Sequences

Sequence LengthMass (Da)Tools
A7N2Q0-1 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: 532ADE6CD1F90AD8

FASTA48652,631
        10         20         30         40         50         60 
MDMKAHYIDG AMHLGCSEEH FTTYNPANGE PLANVKQANQ QDMQAAIESA KRGFAIWSAM 

        70         80         90        100        110        120 
TATERSRILL KAVALLRERN DELAALEVAD TGKPIQEANC VDIATGADVI EYYAGLAPSM 

       130        140        150        160        170        180 
HGEQQPLNES QFFYTRREPL GICAGIGAWN YPIQIAMWKS APALAAGNAM IFKPSEETPL 

       190        200        210        220        230        240 
TALKLAEIYS EAGLPDGVFN VIQGDYRVGQ MLTAHPDIAK VSFTGESGTG KVVMGDSAAT 

       250        260        270        280        290        300 
LKQVTMELGG KSPMIIFDDA KLDDAVSAAM VANFYTQGEV CTHGTRVFVH EGIYDEFVVQ 

       310        320        330        340        350        360 
LKKRTELLVV GDPLDEQTQI GALISKEHES KVLSAIEQAK ASKATLLTGG YKVTENGLAS 

       370        380        390        400        410        420 
GNFVVPTVFI DCEDDMPHVQ QEIFGPVMSV LKFSDEDEVI ARANNTDYGL AAGVFTQNLS 

       430        440        450        460        470        480 
RAHRVIHQIQ AGICWINTWG DSPAEMPVGG YKLSGIGREN GVETLTHYTQ TKSVLVHLGD 


FDSPYA

« Hide

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References

[1]Bassler B., Clifton S.W., Fulton L., Delehaunty K., Fronick C., Harrison M., Markivic C., Fulton R., Tin-Wollam A.-M., Shah N., Pepin K., Nash W., Thiruvilangam P., Bhonagiri V., Waters C., Tu K.C., Irgon J., Wilson R.K.
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000790 Genomic DNA. Translation: ABU74072.1.
RefSeqYP_001448299.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID5558345.
GenomeReviewsGene locus VIBHAR_06180 in contig CP000790_GR.
KEGGvha:VIBHAR_06180.
NMPDRfig|338187.4.peg.3648.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAA7N2Q0. APNGYFV.

Family and domain databases

HAMAPMF_00804.
[Tree]
InterProIPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH.
[Graphical view]
Gene3DG3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
PANTHERPTHR11699. Aldehyde_dehyd. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. False negative.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameBETB_VIBHB
AccessionPrimary (citable) accession number: A7N2Q0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: June 16, 2009
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents