A7N1U8 (RLMG_VIBHB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA large subunit methyltransferase G
EC=2.1.1.174

Alternative name(s):
23S rRNA m2G1835 methyltransferase
rRNA (guanine-N(2)-)-methyltransferase RlmG

Gene names

Name:	rlmG
Ordered Locus Names:	VIBHAR_03277

Organism

Vibrio harveyi (strain ATCC BAA-1116 / BB120) [Complete proteome] [HAMAP]

Taxonomic identifier

338187 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	385 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA By similarity. HAMAP MF_01859
Catalytic activity	S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanosine(1835) in 23S rRNA. HAMAP MF_01859
Subcellular location	Cytoplasm Potential HAMAP MF_01859.
Sequence similarities	Belongs to the methyltransferase superfamily. RlmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA (guanine-N2-)-methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 385	385	Ribosomal RNA large subunit methyltransferase G HAMAP MF_01859		PRO_0000366534

Sequences

	Sequence		Length	Mass (Da)
	A7N1U8 [UniParc]. Last modified October 2, 2007. Version 1. Checksum: 8B74E94B33AF6E6C	FASTA	385	42,912
	10 20 30 40 50 60 MKTELDLHDR SLTLHRFPKR SNETLQAWDA GDEYLINNVE GMALPDNQNI VVVNDNFGAL 70 80 90 100 110 120 ACWFSDRHNV TLMSDSFISH KGAQQNLADN QCNQVSFLST MDDIPENTDL VLMQLPKSNR 130 140 150 160 170 180 HLVWLLSQLR KTLPASCPIV AVNKAKEIHT STLKLFEKYL GETKTSLAWK KHRLVFSTAN 190 200 210 220 230 240 AQPVIDVDPM TIWGIEGEGI QLKNLPNVYS GESLDLGARF MLQHLPQDPT LKHVIDLGCG 250 260 270 280 290 300 NGLLSVKMGQ LNPQARLTSV DESFMAVESA KQNLLDNLGD ARDIQCIANN CLDGFTPDCA 310 320 330 340 350 360 DMVMCNPPFH QQQAITDHIA WQMFCDAKQI LNQGGKLLVI GNRHLGYDAK LKRLFGDKNV 370 380 KLVASNNKFV ILQATKNPAK LGAKQ

References

[1]

The Vibrio harveyi Genome Sequencing Project Bassler B., Clifton S.W., Fulton L., Delehaunty K., Fronick C., Harrison M., Markivic C., Fulton R., Tin-Wollam A.-M., Shah N., Pepin K., Nash W., Thiruvilangam P., Bhonagiri V., Waters C., Tu K.C., Irgon J., Wilson R.K. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1116 / BB120.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000789 Genomic DNA. Translation: ABU72225.1.
RefSeq	YP_001446452.1. NC_009783.1.
3D structure databases
ProteinModelPortal	A7N1U8.
ModBase	Search...
Protein-protein interaction databases
STRING	A7N1U8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5554384.
GenomeReviews	Gene locus VIBHAR_03277 in contig CP000789_GR.
KEGG	vha:VIBHAR_03277.
NMPDR	fig|338187.4.peg.2392.
PATRIC	20133185. VBIVibHar24526_3122.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2813.
HOGENOM	HBG321931.
OMA	NRHLGYH.
ProtClustDB	CLSK874746.
Family and domain databases
HAMAP	MF_01859. 23SrRNA_methyltr_G. [Tree]
InterPro	IPR017237. rRNA_m2G-MeTrfase_RsmD. IPR007848. Small_mtfrase. [Graphical view]
KO	K00564.
Pfam	PF05175. MTS. 1 hit. [Graphical view]
PIRSF	PIRSF037565. RRNA_m2G_Mtase_RsmD_prd. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RLMG_VIBHB

Accession

Primary (citable) accession number: A7N1U8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	October 2, 2007
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program