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A7N1L9

- LFTR_VIBCB

UniProt

A7N1L9 - LFTR_VIBCB

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Protein
Leucyl/phenylalanyl-tRNA--protein transferase
Gene
aat, VIBHAR_01570
Organism
Vibrio campbellii (strain ATCC BAA-1116 / BB120)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciVHAR338187:GJCH-1560-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferase (EC:2.3.2.6)
Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase
Gene namesi
Name:aat
Ordered Locus Names:VIBHAR_01570
OrganismiVibrio campbellii (strain ATCC BAA-1116 / BB120)
Taxonomic identifieri338187 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000008152: Chromosome I

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 236236Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation
PRO_1000045118Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi338187.VIBHAR_01570.

Structurei

3D structure databases

ProteinModelPortaliA7N1L9.

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102325.
KOiK00684.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

A7N1L9-1 [UniParc]FASTAAdd to Basket

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MAIYLTELGD SHSFPSPYDA LNDPNGLLAF GGDLNPDRIL NGYHQGIFPW    50
YGPGEPILWW SPSPRAVFDP LAFKPSKSLK KFQRKQQYKV TLNNATERVI 100
QLCSSTRSAE ETWLNEEMQT SYIELARRGH CHSVEVWHDE KLIGGLYGIS 150
VGQLFCGESM FSLKDNASKI ALWYLCEHLA SNQGQLIDCQ VMNPHLASLG 200
AFELERDDFV QKLLSLRDRN INLGTFEPQV LQGAVS 236
Length:236
Mass (Da):26,621
Last modified:October 2, 2007 - v1
Checksum:i94A9153A5DA10567
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000789 Genomic DNA. Translation: ABU70540.1.
RefSeqiYP_001444767.1. NC_009783.1.
YP_008525834.1. NC_022269.1.

Genome annotation databases

EnsemblBacteriaiABU70540; ABU70540; VIBHAR_01570.
GeneIDi16815227.
5553425.
KEGGivca:M892_05280.
vha:VIBHAR_01570.
PATRICi20129937. VBIVibHar24526_1511.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000789 Genomic DNA. Translation: ABU70540.1 .
RefSeqi YP_001444767.1. NC_009783.1.
YP_008525834.1. NC_022269.1.

3D structure databases

ProteinModelPortali A7N1L9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 338187.VIBHAR_01570.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABU70540 ; ABU70540 ; VIBHAR_01570 .
GeneIDi 16815227.
5553425.
KEGGi vca:M892_05280.
vha:VIBHAR_01570.
PATRICi 20129937. VBIVibHar24526_1511.

Phylogenomic databases

eggNOGi COG2360.
HOGENOMi HOG000102325.
KOi K00684.
OrthoDBi EOG6WX4R3.

Enzyme and pathway databases

BioCyci VHAR338187:GJCH-1560-MONOMER.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1116 / BB120.

Entry informationi

Entry nameiLFTR_VIBCB
AccessioniPrimary (citable) accession number: A7N1L9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: May 14, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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