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Protein

2-dehydro-3-deoxyphosphooctonate aldolase

Gene

kdsA

Organism
Vibrio campbellii (strain ATCC BAA-1116 / BB120)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciVHAR338187:GJCH-1244-MONOMER.
UniPathwayiUPA00030.
UPA00357; UER00474.

Names & Taxonomyi

Protein namesi
Recommended name:
2-dehydro-3-deoxyphosphooctonate aldolaseUniRule annotation (EC:2.5.1.55UniRule annotation)
Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthaseUniRule annotation
KDO-8-phosphate synthaseUniRule annotation
Short name:
KDO 8-P synthaseUniRule annotation
Short name:
KDOPSUniRule annotation
Phospho-2-dehydro-3-deoxyoctonate aldolaseUniRule annotation
Gene namesi
Name:kdsAUniRule annotation
Ordered Locus Names:VIBHAR_01254
OrganismiVibrio campbellii (strain ATCC BAA-1116 / BB120)
Taxonomic identifieri338187 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000008152 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2832832-dehydro-3-deoxyphosphooctonate aldolasePRO_1000003351Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi338187.VIBHAR_01254.

Structurei

3D structure databases

ProteinModelPortaliA7MY69.
SMRiA7MY69. Positions 1-281.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the KdsA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2877.
HOGENOMiHOG000023021.
KOiK01627.
OMAiESRDHAF.
OrthoDBiEOG680X4R.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00056. KDO8P_synth.
InterProiIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
[Graphical view]
PANTHERiPTHR21057:SF2. PTHR21057:SF2. 1 hit.
PfamiPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01362. KDO8P_synth. 1 hit.

Sequencei

Sequence statusi: Complete.

A7MY69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQKIVNIGD IQVANDKPFT LFAGMNVLES RDLAMQICEH YVKVTDKLGI
60 70 80 90 100
PYVFKASFDK ANRSSVHSYR GPGLEEGMKI FQELKDTFGV KIITDVHTEA
110 120 130 140 150
QAQPVADVVD VIQLPAFLAR QTDLVEAMAK TGAVINVKKP QFMSPGQVGN
160 170 180 190 200
IVEKFAECGN ENIILCERGS CMGYDNLVVD MLGFGVMKNA SKGSPIIFDV
210 220 230 240 250
THSLQMRDPS GAASGGRREQ TVELAKAGLA TGIAGLFIEA HPNPDQARCD
260 270 280
GPSALPLDKL EPFLAQMKSL DDLIKSFADI DIK
Length:283
Mass (Da):30,746
Last modified:October 2, 2007 - v1
Checksum:i6464EAE8610FA32F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000789 Genomic DNA. Translation: ABU70233.1.
RefSeqiWP_012127204.1. NC_022269.1.
YP_008526119.1. NC_022269.1.

Genome annotation databases

EnsemblBacteriaiABU70233; ABU70233; VIBHAR_01254.
KEGGivca:M892_06740.
vha:VIBHAR_01254.
PATRICi20129338. VBIVibHar24526_1219.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000789 Genomic DNA. Translation: ABU70233.1.
RefSeqiWP_012127204.1. NC_022269.1.
YP_008526119.1. NC_022269.1.

3D structure databases

ProteinModelPortaliA7MY69.
SMRiA7MY69. Positions 1-281.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi338187.VIBHAR_01254.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABU70233; ABU70233; VIBHAR_01254.
KEGGivca:M892_06740.
vha:VIBHAR_01254.
PATRICi20129338. VBIVibHar24526_1219.

Phylogenomic databases

eggNOGiCOG2877.
HOGENOMiHOG000023021.
KOiK01627.
OMAiESRDHAF.
OrthoDBiEOG680X4R.

Enzyme and pathway databases

UniPathwayiUPA00030.
UPA00357; UER00474.
BioCyciVHAR338187:GJCH-1244-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00056. KDO8P_synth.
InterProiIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006269. KDO8P_synthase.
[Graphical view]
PANTHERiPTHR21057:SF2. PTHR21057:SF2. 1 hit.
PfamiPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01362. KDO8P_synth. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1116 / BB120.

Entry informationi

Entry nameiKDSA_VIBCB
AccessioniPrimary (citable) accession number: A7MY69
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: May 27, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.