A7MWG4 (CYSD_VIBHB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	VIBHAR_00766

Organism

Vibrio harveyi (strain ATCC BAA-1116 / BB120) [Complete proteome] [HAMAP]

Taxonomic identifier

338187 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Vibrionales › Vibrionaceae › Vibrio

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 302	302	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_1000008999

Sequences

	Sequence		Length	Mass (Da)
	A7MWG4 [UniParc]. Last modified October 2, 2007. Version 1. Checksum: F1CFBE6EC5D4E4E1	FASTA	302	34,983
	10 20 30 40 50 60 MDQQRLTHLK QLEAESIHII REVAAEFDNP VMMYSIGKDS SVMLHLARKA FYPGKIPFPL 70 80 90 100 110 120 LHVDTDWKFR EMIEFRDRTA EKYGFELLVH KNPEGLAMGC SPFVHGSSKH TDIMKTQGLK 130 140 150 160 170 180 QALNKYGFDA AFGGARRDEE KSRAKERVYS FRDKNHTWDP KNQRPELWKT YNGQVNKGES 190 200 210 220 230 240 IRVFPLSNWT ELDIWQYIYL ENIEIVPLYL ADKRPVVERD GMLIMVDDDR MKLEPGEVIE 250 260 270 280 290 300 EKSVRFRTLG CYPLTGAIES EANTLTGIIE EMLVATSSER QGRAIDHDQS GSMELKKRQG YF

References

[1]

The Vibrio harveyi Genome Sequencing Project Bassler B., Clifton S.W., Fulton L., Delehaunty K., Fronick C., Harrison M., Markivic C., Fulton R., Tin-Wollam A.-M., Shah N., Pepin K., Nash W., Thiruvilangam P., Bhonagiri V., Waters C., Tu K.C., Irgon J., Wilson R.K. Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1116 / BB120.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000789 Genomic DNA. Translation: ABU69767.1.
RefSeq	YP_001443994.1. NC_009783.1.
3D structure databases
ProteinModelPortal	A7MWG4.
SMR	A7MWG4. Positions 5-211.
ModBase	Search...
Protein-protein interaction databases
STRING	A7MWG4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5555553.
GenomeReviews	Gene locus VIBHAR_00766 in contig CP000789_GR.
KEGG	vha:VIBHAR_00766.
NMPDR	fig|338187.4.peg.598.
PATRIC	20128396. VBIVibHar24526_0767.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0175.
HOGENOM	HBG758022.
OMA	RVIDHDA.
ProtClustDB	PRK05253.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_VIBHB

Accession

Primary (citable) accession number: A7MWG4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 2, 2007
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program