ID   ASTE_VIBHB              Reviewed;         342 AA.
AC   A7MVW7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   16-JUN-2009, entry version 13.
DE   RecName: Full=Succinylglutamate desuccinylase;
DE            EC=3.5.1.96;
GN   Name=astE; OrderedLocusNames=VIBHAR_02131;
OS   Vibrio harveyi (strain ATCC BAA-1116 / BB120).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio.
OX   NCBI_TaxID=338187;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Bassler B., Clifton S.W., Fulton L., Delehaunty K., Fronick C.,
RA   Harrison M., Markivic C., Fulton R., Tin-Wollam A.-M., Shah N.,
RA   Pepin K., Nash W., Thiruvilangam P., Bhonagiri V., Waters C., Tu K.C.,
RA   Irgon J., Wilson R.K.;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transforms N(2)-succinylglutamate into succinate and
CC       glutamate (By similarity).
CC   -!- CATALYTIC ACTIVITY: N-succinyl-L-glutamate + H(2)O = succinate +
CC       L-glutamate.
CC   -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity).
CC   -!- PATHWAY: Amino-acid degradation; L-arginine degradation via AST
CC       pathway; L-glutamate and succinate from L-arginine: step 5/5.
CC   -!- SIMILARITY: Belongs to the aspA/astE family. Succinylglutamate
CC       desuccinylase subfamily.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000789; ABU71096.1; -; Genomic_DNA.
DR   RefSeq; YP_001445323.1; -.
DR   GeneID; 5554743; -.
DR   GenomeReviews; CP000789_GR; VIBHAR_02131.
DR   KEGG; vha:VIBHAR_02131; -.
DR   NMPDR; fig|338187.4.peg.1584; -.
DR   OMA; A7MVW7; EKFAIYP.
DR   GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:HAMAP.
DR   GO; GO:0009017; F:succinylglutamate desuccinylase activity; IEA:EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019544; P:arginine catabolic process to glutamate; IEA:HAMAP.
DR   HAMAP; MF_00767; -; 1.
DR   InterPro; IPR007036; Aste_AspA.
DR   InterPro; IPR016681; SuccinylGlu_desuccinylase.
DR   Pfam; PF04952; AstE_AspA; 1.
DR   PIRSF; PIRSF017020; AstE; 1.
PE   3: Inferred from homology;
KW   Arginine metabolism; Complete proteome; Hydrolase; Metal-binding;
KW   Zinc.
FT   CHAIN         1    342       Succinylglutamate desuccinylase.
FT                                /FTId=PRO_1000017333.
FT   ACT_SITE    219    219       Potential.
FT   METAL        63     63       Zinc (By similarity).
FT   METAL        66     66       Zinc (By similarity).
FT   METAL       155    155       Zinc (By similarity).
SQ   SEQUENCE   342 AA;  38827 MW;  A365853723E8D2F8 CRC64;
     MTKSLFRQSF LTDTLDVHID VAPAEQVLSN GVKLKLYQRG VLEVIPEEYT QETKNVIISC
     GVHGDETAPM ELVDSIIKDI ESGFQKVEAR CLFIIAHPES TLAHSRFLEE NLNRLFDEKE
     HEPTKELAIA DTLKLLVRDF YQDTAAETRW HLDLHCAIRA SKHYTFAVSP KTRHPVRSKA
     LIDFLDSAHI EAVLLSNSPT STFSWFSAEN YGAQALTMEL GRVARIGEND LDKLTAFDLS
     LRNLIAESKA EHLSKPCIKY RVSRTIVRLH EDFDFMFDDN VENFTSFVHG EVFGHDGDKP
     LMAKNDNEAV VFPNRHVAIG QRAALMVCEV KTRYEDGELV YD
//