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Protein

Exodeoxyribonuclease 7 large subunit

Gene

xseA

Organism
Vibrio campbellii (strain ATCC BAA-1116 / BB120)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciVCAM338187:G1HKJ-1531-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII large subunitUniRule annotation
Short name:
Exonuclease VII large subunitUniRule annotation
Gene namesi
Name:xseAUniRule annotation
Ordered Locus Names:VIBHAR_01075
OrganismiVibrio campbellii (strain ATCC BAA-1116 / BB120)
Taxonomic identifieri338187 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000008152 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000487911 – 443Exodeoxyribonuclease 7 large subunitAdd BLAST443

Proteomic databases

PRIDEiA7MU31

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Protein-protein interaction databases

STRINGi338187.VIBHAR_01075

Structurei

3D structure databases

SMRiA7MU31
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DVS Bacteria
COG1570 LUCA
HOGENOMiHOG000229265
KOiK03601
OMAiNARRRWP

Family and domain databases

CDDicd04489 ExoVII_LU_OBF, 1 hit
HAMAPiMF_00378 Exonuc_7_L, 1 hit
InterProiView protein in InterPro
IPR003753 Exonuc_VII_L
IPR020579 Exonuc_VII_lsu_C
IPR025824 OB-fold_nuc-bd_dom
PANTHERiPTHR30008 PTHR30008, 1 hit
PfamiView protein in Pfam
PF02601 Exonuc_VII_L, 1 hit
PF13742 tRNA_anti_2, 1 hit
TIGRFAMsiTIGR00237 xseA, 1 hit

Sequencei

Sequence statusi: Complete.

A7MU31-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSQTNQNIF TVSRLNAEVR LLLENEMGIV WLVGEISNFS APVSGHWYLT
60 70 80 90 100
LKDSRAQVKC AMFRGNNRRV TFKPANGNQV LVKARLSLYE PRGDYQLIIE
110 120 130 140 150
SMQPEGDGRL QQEFEALKMK LAAEGLFAQT NKQPLPEHPK RVGVITSKTG
160 170 180 190 200
AALYDILDVL KRRDPSLPVV VYPTMVQGEE AAIQMAQAIG RANSRDECDV
210 220 230 240 250
LIVGRGGGSL EDLWCFNNEI LARTIAASQI PIISAVGHEV DVTIADFVAD
260 270 280 290 300
IRAPTPSAAA ELVSRDNSHK DQALVTHQHK LASAMRYYLA QQKQQSAQLM
310 320 330 340 350
HRLERQHPSY QLQRQTQQLD ELEMRLQRAM QRFITTRQQA VERKHHRLQL
360 370 380 390 400
NSPVKRLAEQ KSKLDRVEQK LLDAMDRKLL TMRHQLAIAA EKLDTVSPLA
410 420 430 440
TLKRGYSITQ TEQGQVVTQA KDVKTGDVLV TRLSDGELRS TVN
Length:443
Mass (Da):49,854
Last modified:October 2, 2007 - v1
Checksum:i38CA4E6116D1F298
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000789 Genomic DNA Translation: ABU70068.1
RefSeqiWP_012127095.1, NC_022269.1

Genome annotation databases

EnsemblBacteriaiABU70068; ABU70068; VIBHAR_01075
GeneIDi5555978
KEGGivca:M892_07545
vha:VIBHAR_01075
PATRICifig|338187.25.peg.1552

Similar proteinsi

Entry informationi

Entry nameiEX7L_VIBCB
AccessioniPrimary (citable) accession number: A7MU31
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: May 23, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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