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A7MU31 (EX7L_VIBCB) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Exodeoxyribonuclease 7 large subunit

EC=3.1.11.6
Alternative name(s):
Exodeoxyribonuclease VII large subunit
Short name=Exonuclease VII large subunit
Gene names
Name:xseA
Ordered Locus Names:VIBHAR_01075
OrganismVibrio campbellii (strain ATCC BAA-1116 / BB120) [Complete proteome] [HAMAP]
Taxonomic identifier338187 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length443 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity. HAMAP-Rule MF_00378

Catalytic activity

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP-Rule MF_00378

Subunit structure

Heterooligomer composed of large and small subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00378.

Sequence similarities

Belongs to the XseA family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionExonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

exodeoxyribonuclease VII complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionexodeoxyribonuclease VII activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

nucleic acid binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 443443Exodeoxyribonuclease 7 large subunit HAMAP-Rule MF_00378
PRO_1000048791

Sequences

Sequence LengthMass (Da)Tools
A7MU31 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: 38CA4E6116D1F298

FASTA44349,854
        10         20         30         40         50         60 
MLSQTNQNIF TVSRLNAEVR LLLENEMGIV WLVGEISNFS APVSGHWYLT LKDSRAQVKC 

        70         80         90        100        110        120 
AMFRGNNRRV TFKPANGNQV LVKARLSLYE PRGDYQLIIE SMQPEGDGRL QQEFEALKMK 

       130        140        150        160        170        180 
LAAEGLFAQT NKQPLPEHPK RVGVITSKTG AALYDILDVL KRRDPSLPVV VYPTMVQGEE 

       190        200        210        220        230        240 
AAIQMAQAIG RANSRDECDV LIVGRGGGSL EDLWCFNNEI LARTIAASQI PIISAVGHEV 

       250        260        270        280        290        300 
DVTIADFVAD IRAPTPSAAA ELVSRDNSHK DQALVTHQHK LASAMRYYLA QQKQQSAQLM 

       310        320        330        340        350        360 
HRLERQHPSY QLQRQTQQLD ELEMRLQRAM QRFITTRQQA VERKHHRLQL NSPVKRLAEQ 

       370        380        390        400        410        420 
KSKLDRVEQK LLDAMDRKLL TMRHQLAIAA EKLDTVSPLA TLKRGYSITQ TEQGQVVTQA 

       430        440 
KDVKTGDVLV TRLSDGELRS TVN 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000789 Genomic DNA. Translation: ABU70068.1.
RefSeqYP_001444295.1. NC_009783.1.
YP_008526275.1. NC_022269.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING338187.VIBHAR_01075.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABU70068; ABU70068; VIBHAR_01075.
GeneID16815678.
5555978.
KEGGvca:M892_07545.
vha:VIBHAR_01075.
PATRIC20128994. VBIVibHar24526_1058.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1570.
HOGENOMHOG000229265.
KOK03601.
OrthoDBEOG64R65J.

Enzyme and pathway databases

BioCycVHAR338187:GJCH-1066-MONOMER.

Family and domain databases

HAMAPMF_00378. Exonuc_7_L.
InterProIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsTIGR00237. xseA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameEX7L_VIBCB
AccessionPrimary (citable) accession number: A7MU31
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families