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A7MU31

- EX7L_VIBCB

UniProt

A7MU31 - EX7L_VIBCB

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Protein

Exodeoxyribonuclease 7 large subunit

Gene
xseA, VIBHAR_01075
Organism
Vibrio campbellii (strain ATCC BAA-1116 / BB120)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

  1. exodeoxyribonuclease VII activity Source: UniProtKB-HAMAP
  2. nucleic acid binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciVHAR338187:GJCH-1066-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 large subunit (EC:3.1.11.6)
Alternative name(s):
Exodeoxyribonuclease VII large subunit
Short name:
Exonuclease VII large subunit
Gene namesi
Name:xseA
Ordered Locus Names:VIBHAR_01075
OrganismiVibrio campbellii (strain ATCC BAA-1116 / BB120)
Taxonomic identifieri338187 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000008152: Chromosome I

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. exodeoxyribonuclease VII complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 443443Exodeoxyribonuclease 7 large subunitUniRule annotationPRO_1000048791Add
BLAST

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits By similarity.

Protein-protein interaction databases

STRINGi338187.VIBHAR_01075.

Family & Domainsi

Sequence similaritiesi

Belongs to the XseA family.

Phylogenomic databases

eggNOGiCOG1570.
HOGENOMiHOG000229265.
KOiK03601.
OrthoDBiEOG64R65J.

Family and domain databases

HAMAPiMF_00378. Exonuc_7_L.
InterProiIPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view]
PfamiPF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00237. xseA. 1 hit.

Sequencei

Sequence statusi: Complete.

A7MU31-1 [UniParc]FASTAAdd to Basket

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MLSQTNQNIF TVSRLNAEVR LLLENEMGIV WLVGEISNFS APVSGHWYLT    50
LKDSRAQVKC AMFRGNNRRV TFKPANGNQV LVKARLSLYE PRGDYQLIIE 100
SMQPEGDGRL QQEFEALKMK LAAEGLFAQT NKQPLPEHPK RVGVITSKTG 150
AALYDILDVL KRRDPSLPVV VYPTMVQGEE AAIQMAQAIG RANSRDECDV 200
LIVGRGGGSL EDLWCFNNEI LARTIAASQI PIISAVGHEV DVTIADFVAD 250
IRAPTPSAAA ELVSRDNSHK DQALVTHQHK LASAMRYYLA QQKQQSAQLM 300
HRLERQHPSY QLQRQTQQLD ELEMRLQRAM QRFITTRQQA VERKHHRLQL 350
NSPVKRLAEQ KSKLDRVEQK LLDAMDRKLL TMRHQLAIAA EKLDTVSPLA 400
TLKRGYSITQ TEQGQVVTQA KDVKTGDVLV TRLSDGELRS TVN 443
Length:443
Mass (Da):49,854
Last modified:October 2, 2007 - v1
Checksum:i38CA4E6116D1F298
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000789 Genomic DNA. Translation: ABU70068.1.
RefSeqiYP_001444295.1. NC_009783.1.
YP_008526275.1. NC_022269.1.

Genome annotation databases

EnsemblBacteriaiABU70068; ABU70068; VIBHAR_01075.
GeneIDi16815678.
5555978.
KEGGivca:M892_07545.
vha:VIBHAR_01075.
PATRICi20128994. VBIVibHar24526_1058.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000789 Genomic DNA. Translation: ABU70068.1 .
RefSeqi YP_001444295.1. NC_009783.1.
YP_008526275.1. NC_022269.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 338187.VIBHAR_01075.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABU70068 ; ABU70068 ; VIBHAR_01075 .
GeneIDi 16815678.
5555978.
KEGGi vca:M892_07545.
vha:VIBHAR_01075.
PATRICi 20128994. VBIVibHar24526_1058.

Phylogenomic databases

eggNOGi COG1570.
HOGENOMi HOG000229265.
KOi K03601.
OrthoDBi EOG64R65J.

Enzyme and pathway databases

BioCyci VHAR338187:GJCH-1066-MONOMER.

Family and domain databases

HAMAPi MF_00378. Exonuc_7_L.
InterProi IPR003753. Exonuc_VII_L.
IPR020579. Exonuc_VII_lsu_C.
IPR025824. OB-fold_nuc-bd_dom.
[Graphical view ]
Pfami PF02601. Exonuc_VII_L. 1 hit.
PF13742. tRNA_anti_2. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00237. xseA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1116 / BB120.

Entry informationi

Entry nameiEX7L_VIBCB
AccessioniPrimary (citable) accession number: A7MU31
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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