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A7MTN6

- GLSA_VIBCB

UniProt

A7MTN6 - GLSA_VIBCB

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Protein
Glutaminase
Gene
glsA, VIBHAR_03588
Organism
Vibrio campbellii (strain ATCC BAA-1116 / BB120)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei64 – 641Substrate By similarity
Binding sitei115 – 1151Substrate By similarity
Binding sitei159 – 1591Substrate By similarity
Binding sitei166 – 1661Substrate By similarity
Binding sitei190 – 1901Substrate By similarity
Binding sitei242 – 2421Substrate By similarity
Binding sitei260 – 2601Substrate; via amide nitrogen By similarity

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciVHAR338187:GJCH-3578-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase (EC:3.5.1.2)
Gene namesi
Name:glsA
Ordered Locus Names:VIBHAR_03588
OrganismiVibrio campbellii (strain ATCC BAA-1116 / BB120)
Taxonomic identifieri338187 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000008152: Chromosome I

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 306306GlutaminaseUniRule annotation
PRO_1000048367Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi338187.VIBHAR_03588.

Structurei

3D structure databases

ProteinModelPortaliA7MTN6.

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

A7MTN6-1 [UniParc]FASTAAdd to Basket

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MKPTAQILTD ILAEVRPLIG QGKVADYIPA LAKVPNTKLG IAVYTNEGEV    50
IKAGDAEESF SIQSISKALS LTLAMCLYKQ EEIWCRVGKE PSGQAFNSMI 100
QLEMEQGIPR NPFINAGAIV VADLLQSRLS APRQRLLEFA RQLSGDTHIV 150
YDKVVAASEM MHGDRNAAIA YLMRSFGNFE NEVIPVLQNY FHACALKMSC 200
VDLAKTFSYL ANKGTSVQTG KPVVSPTQTK QLNALLATCG LYDGAGEFAY 250
RVGMPGKSGV GGGIIAVVPG EMTIAVWSPE LDASGNSLAG TKALELLAER 300
IGRSIF 306
Length:306
Mass (Da):32,846
Last modified:October 2, 2007 - v1
Checksum:i5FFCB7CDFD05DE03
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000789 Genomic DNA. Translation: ABU72523.1.
RefSeqiYP_001446750.1. NC_009783.1.
YP_008527314.1. NC_022269.1.

Genome annotation databases

EnsemblBacteriaiABU72523; ABU72523; VIBHAR_03588.
GeneIDi16816801.
5554071.
KEGGivca:M892_13185.
vha:VIBHAR_03588.
PATRICi20133789. VBIVibHar24526_3412.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000789 Genomic DNA. Translation: ABU72523.1 .
RefSeqi YP_001446750.1. NC_009783.1.
YP_008527314.1. NC_022269.1.

3D structure databases

ProteinModelPortali A7MTN6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 338187.VIBHAR_03588.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABU72523 ; ABU72523 ; VIBHAR_03588 .
GeneIDi 16816801.
5554071.
KEGGi vca:M892_13185.
vha:VIBHAR_03588.
PATRICi 20133789. VBIVibHar24526_3412.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci VHAR338187:GJCH-3578-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1116 / BB120.

Entry informationi

Entry nameiGLSA_VIBCB
AccessioniPrimary (citable) accession number: A7MTN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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