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A7MTN6

- GLSA_VIBCB

UniProt

A7MTN6 - GLSA_VIBCB

Protein

Glutaminase

Gene

glsA

Organism
Vibrio campbellii (strain ATCC BAA-1116 / BB120)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (02 Oct 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei64 – 641SubstrateUniRule annotation
    Binding sitei115 – 1151SubstrateUniRule annotation
    Binding sitei159 – 1591SubstrateUniRule annotation
    Binding sitei166 – 1661SubstrateUniRule annotation
    Binding sitei190 – 1901SubstrateUniRule annotation
    Binding sitei242 – 2421SubstrateUniRule annotation
    Binding sitei260 – 2601Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. glutaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutamine metabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciVHAR338187:GJCH-3578-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
    Gene namesi
    Name:glsAUniRule annotation
    Ordered Locus Names:VIBHAR_03588
    OrganismiVibrio campbellii (strain ATCC BAA-1116 / BB120)
    Taxonomic identifieri338187 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
    ProteomesiUP000008152: Chromosome I

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 306306GlutaminasePRO_1000048367Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi338187.VIBHAR_03588.

    Structurei

    3D structure databases

    ProteinModelPortaliA7MTN6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glutaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2066.
    HOGENOMiHOG000216890.
    KOiK01425.
    OrthoDBiEOG6N94BK.

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    HAMAPiMF_00313. Glutaminase.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view]
    PANTHERiPTHR12544. PTHR12544. 1 hit.
    PfamiPF04960. Glutaminase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56601. SSF56601. 1 hit.
    TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A7MTN6-1 [UniParc]FASTAAdd to Basket

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    MKPTAQILTD ILAEVRPLIG QGKVADYIPA LAKVPNTKLG IAVYTNEGEV    50
    IKAGDAEESF SIQSISKALS LTLAMCLYKQ EEIWCRVGKE PSGQAFNSMI 100
    QLEMEQGIPR NPFINAGAIV VADLLQSRLS APRQRLLEFA RQLSGDTHIV 150
    YDKVVAASEM MHGDRNAAIA YLMRSFGNFE NEVIPVLQNY FHACALKMSC 200
    VDLAKTFSYL ANKGTSVQTG KPVVSPTQTK QLNALLATCG LYDGAGEFAY 250
    RVGMPGKSGV GGGIIAVVPG EMTIAVWSPE LDASGNSLAG TKALELLAER 300
    IGRSIF 306
    Length:306
    Mass (Da):32,846
    Last modified:October 2, 2007 - v1
    Checksum:i5FFCB7CDFD05DE03
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000789 Genomic DNA. Translation: ABU72523.1.
    RefSeqiYP_001446750.1. NC_009783.1.
    YP_008527314.1. NC_022269.1.

    Genome annotation databases

    EnsemblBacteriaiABU72523; ABU72523; VIBHAR_03588.
    GeneIDi16816801.
    5554071.
    KEGGivca:M892_13185.
    vha:VIBHAR_03588.
    PATRICi20133789. VBIVibHar24526_3412.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000789 Genomic DNA. Translation: ABU72523.1 .
    RefSeqi YP_001446750.1. NC_009783.1.
    YP_008527314.1. NC_022269.1.

    3D structure databases

    ProteinModelPortali A7MTN6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 338187.VIBHAR_03588.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABU72523 ; ABU72523 ; VIBHAR_03588 .
    GeneIDi 16816801.
    5554071.
    KEGGi vca:M892_13185.
    vha:VIBHAR_03588.
    PATRICi 20133789. VBIVibHar24526_3412.

    Phylogenomic databases

    eggNOGi COG2066.
    HOGENOMi HOG000216890.
    KOi K01425.
    OrthoDBi EOG6N94BK.

    Enzyme and pathway databases

    BioCyci VHAR338187:GJCH-3578-MONOMER.

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    HAMAPi MF_00313. Glutaminase.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR015868. Glutaminase.
    [Graphical view ]
    PANTHERi PTHR12544. PTHR12544. 1 hit.
    Pfami PF04960. Glutaminase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56601. SSF56601. 1 hit.
    TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-1116 / BB120.

    Entry informationi

    Entry nameiGLSA_VIBCB
    AccessioniPrimary (citable) accession number: A7MTN6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: October 2, 2007
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3