ID   UXAB_ENTS8              Reviewed;         483 AA.
AC   A7MPR2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   16-JUN-2009, entry version 13.
DE   RecName: Full=Altronate oxidoreductase;
DE            EC=1.1.1.58;
DE   AltName: Full=Tagaturonate reductase;
DE   AltName: Full=Tagaturonate dehydrogenase;
GN   Name=uxaB; OrderedLocusNames=ESA_01824;
OS   Enterobacter sakazakii (strain ATCC BAA-894).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Cronobacter.
OX   NCBI_TaxID=290339;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA   Fulton B., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W.,
RA   Johnson M., Thiruvilangam P., Wilson R.;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-altronate + NAD(+) = D-tagaturonate + NADH.
CC   -!- PATHWAY: Carbohydrate metabolism; pentose and glucuronate
CC       interconversion.
CC   -!- SIMILARITY: Belongs to the mannitol dehydrogenase family. UxaB
CC       subfamily.
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DR   EMBL; CP000783; ABU77078.1; -; Genomic_DNA.
DR   RefSeq; YP_001437914.1; -.
DR   GeneID; 5550959; -.
DR   GenomeReviews; CP000783_GR; ESA_01824.
DR   KEGG; esa:ESA_01824; -.
DR   OMA; A7MPR2; SIFPCEL.
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0009026; F:tagaturonate reductase activity; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00670; -; 1.
DR   InterPro; IPR013328; DH_multihelical.
DR   InterPro; IPR013118; Mannitol_DH_C.
DR   InterPro; IPR013131; Mannitol_DH_N.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:1.10.1040.10; Opine_DH; 1.
DR   Pfam; PF01232; Mannitol_dh; 1.
DR   Pfam; PF08125; Mannitol_dh_C; 1.
PE   3: Inferred from homology;
KW   Complete proteome; NAD; Oxidoreductase.
FT   CHAIN         1    483       Altronate oxidoreductase.
FT                                /FTId=PRO_1000044705.
FT   NP_BIND      18     29       NAD (By similarity).
SQ   SEQUENCE   483 AA;  54430 MW;  290D81D64C61243C CRC64;
     MKTLNRRDFP GALWPERIIQ FGEGNFLRAF IDWQVDLLNE HTDLNAGVVV VRPIASDFPP
     SLSTQDGLYT TIIRGLNEKG EAVSESRLIR SVNREISVYA QYDEFLKLAH NPDIRFVFSN
     TTEAGISYHA GDQFDDAPAV SYPAKLTRLL FERFSHFDGA QDKGWVIIPC ELIDYNGEAL
     RELVLRYAHE WALPAAFTTW LESANSFCST LVDRIVTGYP RDEVAQLEES LGYHDAFLDT
     AEHFYLFVIQ GPQWLARELR LDKLPLNVLI VDDIKPYKAR KVAILNGAHT ALVPVAFLAG
     LNTVGEAMND AQICAFVERA IHDEIIPVLD LPRNELESFA DAVVSRFRNP YIKHQLLSIA
     LNGMTKFRTR ILPQLLAGQA QMGTLPPRLT FALAALIAFY RGERNGEGYP LQDDAHWLAR
     FEQLWTQRGD NTITLRELVD AVLSDCEHWE QDLTAVPGLA AQVTRDLDAI LNQGMRHAVA
     PLC
//