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A7MPC2 (G6PI_CROS8) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:ESA_00069
OrganismCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii) [Complete proteome] [HAMAP]
Taxonomic identifier290339 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCronobacter

Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_1000013963

Sites

Active site3551Proton donor By similarity
Active site3861 By similarity
Active site5141 By similarity

Sequences

Sequence LengthMass (Da)Tools
A7MPC2 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: 5C20149D2D162967

FASTA54961,488
        10         20         30         40         50         60 
MKNINPTQTS AWQALQNHFD AMKEVTLAEL FAKDADRFGK FSATFNDQML VDYSKNRITE 

        70         80         90        100        110        120 
ETLSKLLDLA KETDLAGAIK SMFSGEKINR TEDRAVLHVA LRNRSNTPIL VDGKDVMPEV 

       130        140        150        160        170        180 
NAVLEKMKKF SEAIISGEWK GYTGKPITDV VNIGIGGSDL GPFMVTEALR PYKNHLNMHF 

       190        200        210        220        230        240 
VSNVDGTHIA EVLKKVNPES TLFLVASKTF TTQETMTNAH SARDWFLKTA GDEKHVAKHF 

       250        260        270        280        290        300 
AALSTNAKAV GEFGIDTANM FEFWDWVGGR YSLWSAIGLS IILSVGYDNF VELLSGAHEM 

       310        320        330        340        350        360 
DKHFSTTPFE KNLPVLLALI GIWYNNFFGA ETEAILPYDQ YMHRFAAYFQ QGNMESNGKY 

       370        380        390        400        410        420 
VDRNGNAVDY QTGPIIWGEP GTNGQHAFYQ LIHQGTKLVP CDFIAPAITH NPLSDHHQKL 

       430        440        450        460        470        480 
LSNFFAQTEA LAFGKSRDVV EQEFRDQGKD PAQLENVVPF KVFEGNRPTN SILLREITPF 

       490        500        510        520        530        540 
SLGALIALYE HKIFTQGAIL NIFTFDQWGV ELGKQLANRI LPELGDNKEI ASHDSSTNGL 


INRYKAWRG 

« Hide

References

[1]"Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species."
Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L., Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A., Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K., McClelland M., Forsythe S.J.
PLoS ONE 5:E9556-E9556(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-894.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000783 Genomic DNA. Translation: ABU75374.1.
RefSeqYP_001436210.1. NC_009778.1.

3D structure databases

ProteinModelPortalA7MPC2.
SMRA7MPC2. Positions 7-548.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290339.ESA_00069.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABU75374; ABU75374; ESA_00069.
GeneID5548939.
KEGGesa:ESA_00069.
PATRIC20392467. VBICroSak107175_0061.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMALKMHFVS.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycCSAK290339:GJ80-66-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_CROS8
AccessionPrimary (citable) accession number: A7MPC2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: February 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways