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A7MP52

- GLK_CROS8

UniProt

A7MP52 - GLK_CROS8

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Protein

Glucokinase

Gene

glk

Organism
Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi8 – 136ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCSAK290339:GJ80-846-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlucokinaseUniRule annotation (EC:2.7.1.2UniRule annotation)
Alternative name(s):
Glucose kinaseUniRule annotation
Gene namesi
Name:glkUniRule annotation
Ordered Locus Names:ESA_00852
OrganismiCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii)
Taxonomic identifieri290339 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCronobacter
ProteomesiUP000000260: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 321321GlucokinasePRO_1000050968Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi290339.ESA_00852.

Structurei

3D structure databases

ProteinModelPortaliA7MP52.
SMRiA7MP52. Positions 2-321.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial glucokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiPRETQLW.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

A7MP52-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTKYALVGDV GGTNARLALC DVDSGEILKA KTYSGLDYPS LEAVVRVYLE
60 70 80 90 100
EHNATVTDGC IAIACPITGD WVAMTNHVWA FSVAEMKKNL GFDHLEIIND
110 120 130 140 150
FTAVSMAIPM LKTDHLIQFG GGEPQPNKPI AVYGAGTGLG VAHLVHVDKR
160 170 180 190 200
WVSLPGEGGH VDFAPNSEEE AIILEQLRAE VGHVSAERVL SGPGLVNLYR
210 220 230 240 250
AIVKADGRLP DNLRPKDITE RALDDSCTDC RRALSLFCVI MGRFGGNLAL
260 270 280 290 300
TLGTFGGVYI AGGIVPRFLD FFTSSGFRGG FEDKGRFKSY VQDIPVYLIV
310 320
HDQPGLLGAG AHLRQTLGQI L
Length:321
Mass (Da):34,569
Last modified:October 2, 2007 - v1
Checksum:i70AC5F69D73B0786
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000783 Genomic DNA. Translation: ABU76123.1.
RefSeqiYP_001436959.1. NC_009778.1.

Genome annotation databases

EnsemblBacteriaiABU76123; ABU76123; ESA_00852.
GeneIDi5550626.
KEGGiesa:ESA_00852.
PATRICi20393907. VBICroSak107175_0755.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000783 Genomic DNA. Translation: ABU76123.1 .
RefSeqi YP_001436959.1. NC_009778.1.

3D structure databases

ProteinModelPortali A7MP52.
SMRi A7MP52. Positions 2-321.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 290339.ESA_00852.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABU76123 ; ABU76123 ; ESA_00852 .
GeneIDi 5550626.
KEGGi esa:ESA_00852.
PATRICi 20393907. VBICroSak107175_0755.

Phylogenomic databases

eggNOGi COG0837.
HOGENOMi HOG000274469.
KOi K00845.
OMAi PRETQLW.
OrthoDBi EOG64BQ47.

Enzyme and pathway databases

BioCyci CSAK290339:GJ80-846-MONOMER.

Family and domain databases

HAMAPi MF_00524. Glucokinase.
InterProi IPR003836. Glucokinase.
[Graphical view ]
Pfami PF02685. Glucokinase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00749. glk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species."
    Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L., Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A., Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K., McClelland M., Forsythe S.J.
    PLoS ONE 5:E9556-E9556(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-894.

Entry informationi

Entry nameiGLK_CROS8
AccessioniPrimary (citable) accession number: A7MP52
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: October 29, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3