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A7MP52 (GLK_CROS8) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucokinase

EC=2.7.1.2
Alternative name(s):
Glucose kinase
Gene names
Name:glk
Ordered Locus Names:ESA_00852
OrganismCronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii) [Complete proteome] [HAMAP]
Taxonomic identifier290339 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeCronobacter

Protein attributes

Sequence length321 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00524.

Sequence similarities

Belongs to the bacterial glucokinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glucokinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 321321Glucokinase HAMAP-Rule MF_00524
PRO_1000050968

Regions

Nucleotide binding8 – 136ATP Potential

Sequences

Sequence LengthMass (Da)Tools
A7MP52 [UniParc].

Last modified October 2, 2007. Version 1.
Checksum: 70AC5F69D73B0786

FASTA32134,569
        10         20         30         40         50         60 
MTKYALVGDV GGTNARLALC DVDSGEILKA KTYSGLDYPS LEAVVRVYLE EHNATVTDGC 

        70         80         90        100        110        120 
IAIACPITGD WVAMTNHVWA FSVAEMKKNL GFDHLEIIND FTAVSMAIPM LKTDHLIQFG 

       130        140        150        160        170        180 
GGEPQPNKPI AVYGAGTGLG VAHLVHVDKR WVSLPGEGGH VDFAPNSEEE AIILEQLRAE 

       190        200        210        220        230        240 
VGHVSAERVL SGPGLVNLYR AIVKADGRLP DNLRPKDITE RALDDSCTDC RRALSLFCVI 

       250        260        270        280        290        300 
MGRFGGNLAL TLGTFGGVYI AGGIVPRFLD FFTSSGFRGG FEDKGRFKSY VQDIPVYLIV 

       310        320 
HDQPGLLGAG AHLRQTLGQI L 

« Hide

References

[1]"Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species."
Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L., Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A., Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K., McClelland M., Forsythe S.J.
PLoS ONE 5:E9556-E9556(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-894.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000783 Genomic DNA. Translation: ABU76123.1.
RefSeqYP_001436959.1. NC_009778.1.

3D structure databases

ProteinModelPortalA7MP52.
SMRA7MP52. Positions 2-321.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING290339.ESA_00852.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABU76123; ABU76123; ESA_00852.
GeneID5550626.
KEGGesa:ESA_00852.
PATRIC20393907. VBICroSak107175_0755.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0837.
HOGENOMHOG000274469.
KOK00845.
OMADWVEMTN.
OrthoDBEOG64BQ47.
ProtClustDBPRK00292.

Enzyme and pathway databases

BioCycCSAK290339:GJ80-846-MONOMER.

Family and domain databases

HAMAPMF_00524. Glucokinase.
InterProIPR003836. Glucokinase.
[Graphical view]
PfamPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00749. glk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLK_CROS8
AccessionPrimary (citable) accession number: A7MP52
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 2, 2007
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families