A7MNT8 (A7MNT8_CROS8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB HAMAP-Rule MF_01400
EC=1.8.4.12 HAMAP-Rule MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase HAMAP-Rule MF_01400

Gene names

Name:	msrB HAMAP-Rule MF_01400
Ordered Locus Names:	ESA_02169 EMBL ABU77418.1

Organism

Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii) [Complete proteome] [HAMAP] EMBL ABU77418.1

Taxonomic identifier

290339 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Cronobacter › Cronobacter sakazakii

Protein attributes

Sequence length	137 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP-Rule MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity. HAMAP-Rule MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP-Rule MF_01400

Ontologies

Keywords
Ligand	Metal-binding HAMAP-Rule MF_01400 SAAS SAAS011057 Zinc HAMAP-Rule MF_01400 SAAS SAAS011057
Molecular function	Oxidoreductase HAMAP-Rule MF_01400 SAAS SAAS011057
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine (S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	118	1	Nucleophile By similarity HAMAP-Rule MF_01400
	Metal binding	46	1	Zinc By similarity HAMAP-Rule MF_01400
	Metal binding	49	1	Zinc By similarity HAMAP-Rule MF_01400
	Metal binding	95	1	Zinc By similarity HAMAP-Rule MF_01400
	Metal binding	98	1	Zinc By similarity HAMAP-Rule MF_01400

Sequences

	Sequence		Length	Mass (Da)
	A7MNT8 [UniParc]. Last modified October 2, 2007. Version 1. Checksum: 5EE871E611347769	FASTA	137	15,474
	10 20 30 40 50 60 MANQNSQDDL KNTLTEMQFY VTQNHGTEPP YTGRLLHNKR DGVYHCLVCD APLFNSETKY 70 80 90 100 110 120 DSGCGWPSFY EPVSEDSIRY LNDYSHGMQR IEIRCGNCDA HLGHVFPDGP QPTGERYCVN 130 SASLSFTDDD NGEQIKG

References

[1]

"Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species." Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L., Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A., Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K., McClelland M., Forsythe S.J. PLoS ONE 5:E9556-E9556(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-894 EMBL ABU77418.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000783 Genomic DNA. Translation: ABU77418.1.
RefSeq	YP_001438254.1. NC_009778.1.
3D structure databases
ProteinModelPortal	A7MNT8.
SMR	A7MNT8. Positions 4-128.
ModBase	Search...
Protein-protein interaction databases
STRING	290339.ESA_02169.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABU77418; ABU77418; ESA_02169.
GeneID	5549481.
KEGG	esa:ESA_02169.
PATRIC	20396305. VBICroSak107175_1940.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0229.
HOGENOM	HOG000243425.
KO	K07305.
OMA	CKECGSH.
ProtClustDB	PRK00222.
Enzyme and pathway databases
BioCyc	CSAK290339:GJ80-2164-MONOMER.
Family and domain databases
Gene3D	2.170.150.20. 1 hit.
HAMAP	MF_01400. MsrB.
InterPro	IPR002579. Met_Sox_Rdtase_MsrB. IPR011057. Mss4-like. [Graphical view]
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A7MNT8_CROS8

Accession

Primary (citable) accession number: A7MNT8

Entry history

Integrated into UniProtKB/TrEMBL:	October 2, 2007
Last sequence update:	October 2, 2007
Last modified:	May 1, 2013
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)