A7MNG1 (MQO_CROS8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4

Alternative name(s):
MQO
Malate dehydrogenase [quinone]

Gene names

Name:	mqo
Ordered Locus Names:	ESA_03816

Organism

Cronobacter sakazakii (strain ATCC BAA-894) (Enterobacter sakazakii) [Complete proteome] [HAMAP]

Taxonomic identifier

290339 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Cronobacter

Protein attributes

Sequence length	552 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212
Cofactor	FAD By similarity. HAMAP MF_00212
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	malate dehydrogenase (menaquinone) activity Inferred from electronic annotation. Source: EC malate dehydrogenase (quinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 552	552	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_0000325494

Sequences

	Sequence		Length	Mass (Da)
	A7MNG1 [UniParc]. Last modified October 2, 2007. Version 1. Checksum: B7CEAD2327F6EAB8	FASTA	552	60,653
	10 20 30 40 50 60 MSKITLSRKH APAFSLIALL VSSAAYAENT TEKTDVLLIG GGIMSASLGT VLQEIQPDWK 70 80 90 100 110 120 QLMVEKLDGV ALESSNGWNN AGTGHSANME LNYTPEREDG SIDVTKALEI NEAFMISRQF 130 140 150 160 170 180 WSSQVKRGVL NDPHSFINST PHMSFVWGDK NVEYLTKRYQ ALQQTTLFQG MQFSTDQQQI 190 200 210 220 230 240 KKWAPLIIEG RDPKQKVAAT WTPVGTDVNY GEITRQLVGS LKKTSNFKLE TSSEVTDFKR 250 260 270 280 290 300 NADNSWHVTI TDVKSGKEHA VDAKYVFIGA GGGALKLLQK TGIPEADNYA GFPVGGSFLV 310 320 330 340 350 360 SENPEIARQH GEKVYGQASV GAPPMSVPHL DARFLDGKRV VLFGPFATFS TKFLKNGSFF 370 380 390 400 410 420 DLLSTTTTSN FMPMTDVGLD NFDLVKYLIG QVMLSDEDRF EALKEYYPTA RKEDWKLIQA 430 440 450 460 470 480 GQRVQIIKKD PEKGGVLKLG TEIVTDQQKT LAALLGASPG ASTAAPISIN VIKQLFPEQF 490 500 510 520 530 540 KSEAWQSKLR EIVPSYGQKL NGNVALTQQV WDETAATLQL TKPPVIQMKD AKPATPEAKP 550 AQASSPQHDM AL

References

[1]

"Genome sequence of Cronobacter sakazakii BAA-894 and comparative genomic hybridization analysis with other Cronobacter species." Kucerova E., Clifton S.W., Xia X.Q., Long F., Porwollik S., Fulton L., Fronick C., Minx P., Kyung K., Warren W., Fulton R., Feng D., Wollam A., Shah N., Bhonagiri V., Nash W.E., Hallsworth-Pepin K., Wilson R.K., McClelland M., Forsythe S.J. PLoS ONE 5:E9556-E9556(2010) [PubMed: 20221447] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-894.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000783 Genomic DNA. Translation: ABU79002.1.
RefSeq	YP_001439838.1. NC_009778.1.
3D structure databases
ProteinModelPortal	A7MNG1.
ModBase	Search...
Protein-protein interaction databases
STRING	A7MNG1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5548634.
GenomeReviews	Gene locus ESA_03816 in contig CP000783_GR.
KEGG	esa:ESA_03816.
PATRIC	20399313. VBICroSak107175_3390.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0579.
HOGENOM	HBG289663.
OMA	HSANMEL.
ProtClustDB	PRK05257.
Family and domain databases
HAMAP	MF_00212. MQO. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
KO	K00116.
PANTHER	PTHR13847:SF14. PTHR13847:SF14. 1 hit.
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. Mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_CROS8

Accession

Primary (citable) accession number: A7MNG1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	October 2, 2007
Last modified:	January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program