ID   MTLD_ENTS8              Reviewed;         382 AA.
AC   A7MNE5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   16-JUN-2009, entry version 13.
DE   RecName: Full=Mannitol-1-phosphate 5-dehydrogenase;
DE            EC=1.1.1.17;
GN   Name=mtlD; OrderedLocusNames=ESA_03878;
OS   Enterobacter sakazakii (strain ATCC BAA-894).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Cronobacter.
OX   NCBI_TaxID=290339;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA   Fulton B., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W.,
RA   Johnson M., Thiruvilangam P., Wilson R.;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-mannitol 1-phosphate + NAD(+) = D-fructose
CC       6-phosphate + NADH.
CC   -!- SIMILARITY: Belongs to the mannitol dehydrogenase family.
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DR   EMBL; CP000783; ABU79064.1; -; Genomic_DNA.
DR   RefSeq; YP_001439900.1; -.
DR   GeneID; 5548780; -.
DR   GenomeReviews; CP000783_GR; ESA_03878.
DR   KEGG; esa:ESA_03878; -.
DR   OMA; A7MNE5; VDRIVPN.
DR   GO; GO:0050662; F:coenzyme binding; IEA:InterPro.
DR   GO; GO:0008926; F:mannitol-1-phosphate 5-dehydrogenase activity; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00196; -; 1.
DR   InterPro; IPR013328; DH_multihelical.
DR   InterPro; IPR013118; Mannitol_DH_C.
DR   InterPro; IPR000669; Mannitol_DH_core.
DR   InterPro; IPR013131; Mannitol_DH_N.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   Gene3D; G3DSA:1.10.1040.10; Opine_DH; 1.
DR   Pfam; PF01232; Mannitol_dh; 1.
DR   Pfam; PF08125; Mannitol_dh_C; 1.
DR   PRINTS; PR00084; MTLDHDRGNASE.
DR   PROSITE; PS00974; MANNITOL_DHGENASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; NAD; Oxidoreductase.
FT   CHAIN         1    382       Mannitol-1-phosphate 5-dehydrogenase.
FT                                /FTId=PRO_1000011797.
FT   NP_BIND       3     14       NAD (By similarity).
SQ   SEQUENCE   382 AA;  41147 MW;  422F867465D14896 CRC64;
     MKALHFGAGN IGRGFIGKLL ADAGVGLTFA DVNQTVLDAL NARHSYQVRV VGEQEQIDTV
     SGVDAVNSTS EDVVTLIATV DLVTTAVGPV VLERIAPAIA KGLVLRKAQG NERPLNIIAC
     ENMVRGTSQL KTHVFNALEE GDKAWVESHI GFVDSAVDRI VPPSASAAHD PLEVTVETFS
     EWIVDKTQFK GELPTIAGME LTDNLMAFVE RKLFTLNTGH AITAYLGKQA GHQTIRDAIL
     DEKIRLVVRG AMEESGAVLI KRYGFDDAKH AAYIEKILSR FENPYLKDDV ERVGRQPLRK
     LSAGDRLIKP LLGTLEYGLP HQNLVLGIAA AMHFRSEDDP QAQELAQLIA DKGPQAALAQ
     ISGLDANSDV VASAVNAYNA TA
//